Patents by Inventor Ming-Chi HSIEH

Ming-Chi HSIEH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10913069
    Abstract: An apparatus for amplifying a nucleic acid sequence in a polymerase chain reaction (PCR) is provided. The apparatus comprises a microprocessor configured to communicatively couple with a user input device and receive instructions from the user input device and implement the received instructions; an electromagnetic radiation (EMR) generator configured to generated EMR at frequencies ranging from 300 THz to 400 THz and communicatively coupled with the microprocessor; a reaction vessel, communicatively coupled with the microprocessor, to house the nucleic acid sequence, necessary reagents to the PCR, and particles comprising a transition metal material, and to receive the EMR generated by the EMR generator; and a temperature sensor communicatively coupled with the reaction vessel and the microprocessor.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: February 9, 2021
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Dar-Bin Shieh, Chih-Chia Huang, Chen-Min Chang, Tsung-Ju Li, Po-Yang Chang, Ming-Chi Hsieh
  • Publication number: 20190143334
    Abstract: An apparatus for amplifying a nucleic acid sequence in a polymerase chain reaction (PCR) is provided. The apparatus comprises a microprocessor configured to communicatively couple with a user input device and receive instructions from the user input device and implement the received instructions; an electromagnetic radiation (EMR) generator configured to generated EMR at frequencies ranging from 300 THz to 400 THz and communicatively coupled with the microprocessor; a reaction vessel, communicatively coupled with the microprocessor, to house the nucleic acid, sequence, necessary reagents to the PCR, and particles comprising a transition metal material, and to receive the EMR generated by the EMR generator; and a temperature sensor communicatively coupled with the reaction vessel and the microprocessor.
    Type: Application
    Filed: January 10, 2019
    Publication date: May 16, 2019
    Inventors: Dar-Bin SHIEH, Chih-Chia HUANG, Chen-Min CHANG, Tsung-Ju LI, Po-Yang CHANG, Ming-Chi HSIEH
  • Patent number: 10213785
    Abstract: Method and apparatus for amplifying a target nucleic acid sequence of a reaction mixture in a Polymerase Chain Reaction (PCR). The method includes contacting the reaction mixture with EMR frequency absorbing particles formed from a material having a transition metal, transition metal oxide or a transition metal hydroxide, or a nitride, a phosphide or an arsenide of a Group III metal doped with the transition metal or a transition metal oxide, or silicon dioxide doped with the transition metal, transition metal oxide, or transition metal hydroxide; and irradiating the EMR absorbing particles with EMR having a frequency of about 200 kHz to 500 THz to amplify the target nucleic acid sequence, wherein the Group III metal is any one of Al, Ga, and In, and the transition metal is any one of Mn, Fe, Co and Cu.
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: February 26, 2019
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Dar-Bin Shieh, Chih-Chia Huang, Chen-Min Chang, Tsung-Ju Li, Po-Yang Chang, Ming-Chi Hsieh
  • Publication number: 20160060672
    Abstract: Method and apparatus for amplifying a target nucleic acid sequence of a reaction mixture in a Polymerase Chain Reaction (PCR). The method includes contacting the reaction mixture with EMR frequency absorbing particles formed from a material having a transition metal, transition metal oxide or a transition metal hydroxide, or a nitride, a phosphide or an arsenide of a Group III metal doped with the transition metal or a transition metal oxide, or silicon dioxide doped with the transition metal, transition metal oxide, or transition metal hydroxide; and irradiating the EMR absorbing particles with EMR having a frequency of about 200 kHz to 500 THz to amplify the target nucleic acid sequence, wherein the Group III metal is any one of Al, Ga, and In, and the transition metal is any one of Mn, Fe, Co and Cu.
    Type: Application
    Filed: August 31, 2015
    Publication date: March 3, 2016
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Dar-Bin SHIEH, Chih-Chia HUANG, Chen-Min CHANG, Tsung-Ju LI, Po-Yang CHANG, Ming-Chi HSIEH