Abstract: The present invention discloses the use of winter melon wax as a preservative and an antimicrobial agent. In addition, the present invention also discloses a kind of powder of artificial winter melon wax, which is obtained by spray drying the solution of following components with ratios by weight: 30-55% triterpenenol, 10%-20% triterpenenol acetate and 35-60% wax. Experiments proved that the natural winter melon wax and the artificial Winter melon wax powder prepared by the invention had antiseptic and anti-microbial effects, could significantly improve the shelf life of fruits, and had a promoting effect on wound healing.

Abstract: The present invention provides extracts of Lycium barbarum useful for inhibiting, interfering and/or controlling pathological angiogenesis or neovascularization of tissues. The invention also provides a method for treating a disease associated with angiogenesis or neovascularization in a subject, comprising administering an effective amount of an extract of Lycium barbarum to the subject.

Abstract: The present invention provides extracts of Trapa natans L. useful for inhibiting, interfering and/or controlling pathological angiogenesis or neovascularization of tissues. The invention also provides a method to inhibit metastatis of cancer of colon, lung, liver, kidney, breast and/or cervix in a subject, comprising administering an effective amount of an extract of Trapa natans L. to the subject.

Abstract: The present invention provides extracts of Trapa natans L. useful for inhibiting, interfering and/or controlling pathological angiogenesis or neovascularization of tissues. The invention also provides a method to inhibit metastatis of cancer of colon, lung, liver, kidney, breast and/or cervix in a subject, comprising administering an effective amount of an extract of Trapa natans L. to the subject.

Abstract: The present invention provides extracts of Lycium barbarum useful for inhibiting, interfering and/or controlling pathological angiogenesis or neovascularization of tissues. The invention also provides a method to inhibit metastasis of cancer of colon, lung, liver, kidney, breast and/or cervix in a subject, comprising administering an effective amount of an extract of Lycium barbarum to the subject.

Abstract: The present invention provides extracts of Stephaniae sinica Diels useful for inhibiting, interfering and/or controlling pathological angiogenesis or neovascularization of tissues. The invention also provides a method to inhibit metastatis of cancer of colon, lung, liver, kidney, breast and/or cervix in a subject, comprising administering an effective amount of an extract of Stephaniae sinica Diels to the subject.

Abstract: This invention also provides a method to inhibit neovascularization in tissue by delivering to the cell or tissue an effective amount of gossypol, or a pharmaceutically acceptable salt, derivative or prodrug thereof. Also provided herein is a method for treating a disease associated with hyproliferation of endothelial cells and/or neovascularization by administering to a subject an effective amount of gossypol, or a pharmaceutically acceptable salt, derivative or prodrug thereof. Kits to treat patients are provided as well.

Abstract: This invention provides processes to obtain pharmaceutically active fractions from the fungus Ganoderma Lucidum. In one aspect, the process requires extracting from a homogenate of Ganoderma Lucidum a fraction isolated by column chromatography that has an optical absorbance between about 200 nm to about 280 nm. The compound and extracts are useful to inhibit the growth of endothelial cells and to inhibit vascularization in a tissue. Methods of treating various diseases, including cancer and arthritis, are also provided herein.

Abstract: This invention also provides a method to inhibit neovascularization in tissue by delivering to the cell or tissue an effective amount of gossypol, or a pharmaceutically acceptable salt, derivative or prodrug thereof. Also provided herein is a method for treating a disease associated with hyproliferation of endothelial cells and/or neovascularization by administering to a subject an effective amount of gossypol, or a pharmaceutically acceptable salt, derivative or prodrug thereof. Kits to treat patients are provided as well.