Patents by Inventor Ming-Fa Hsieh

Ming-Fa Hsieh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210220491
    Abstract: This invention provides an imaging method for detecting a volume of animal or human to obtain a fluorescence image of the volume. The method comprises steps of: treating the animal or human with an dosage form containing a dye encapsulated by a polymer; irradiating the volume of the animal or human by a light, and detecting a single photon, two- or multi-photon fluorescence emission light from the illuminated volume to obtain a fluorescence image, wherein a peak wavelength of the single photon fluorescence emission light of the dosage form is equal to or greater than 780 nm, or a peak wavelength of the two or multi-photon fluorescence emission light of the dosage form is equal to or greater than 800 nm. This invention further provides an imaging system employing the foregoing imaging method.
    Type: Application
    Filed: January 15, 2021
    Publication date: July 22, 2021
    Inventors: Ming-Fa Hsieh, Shang-Ting Tsai, Tzu-Chau Lin, Wen-Tyng Li, Tzong-Rong Ger, Shyh-Chuan Jwo
  • Publication number: 20150293130
    Abstract: The present invention discloses a system for testing microfluid which is made with a disposable disc. The high sensitivity, high sensing accuracy, and quick response microfluidic disc is demonstrated in the present invention. It is note that easy to test microfluid without traditional detecting method, and then reduce energy and simplify procedure. Furthermore, to additive the microfluidic disc is useful to enhance blood typing, and hence raising the sensitivity by the video recognition of blood agglutination.
    Type: Application
    Filed: June 24, 2015
    Publication date: October 15, 2015
    Inventors: Ging-Ho Hsiue, Shia-Chung Chen, Wen-Tyng Li, Yaw-Jen Chang, Yung Chang, Yi-Hua Fan, Ming-Fa Hsieh, Wei-Liang Liao, Ching-En Chen, Ching-Wei Huang, Ying-Ming Liang
  • Patent number: 9091699
    Abstract: The present invention discloses a system for testing microfluid which is made with a disposable disc. The high sensitivity, high sensing accuracy, and quick response microfluidic disc is demonstrated in the present invention. It is note that easy to test microfluid without traditional detecting method, and then reduce energy and simplify procedure. Furthermore, to additive the microfluidic disc is useful to enhance blood typing, and hence raising the sensitivity by the video recognition of blood agglutination.
    Type: Grant
    Filed: April 16, 2013
    Date of Patent: July 28, 2015
    Assignee: CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Ging-Ho Hsiue, Shia-Chung Chen, Wen-Tyng Li, Yaw-Jen Chang, Yung Chang, Yi-Hua Fan, Ming-Fa Hsieh, Wei-Liang Liao, Ching-En Chen, Ching-Wei Huang, Ying-Ming Liang
  • Patent number: 8940333
    Abstract: An amphiphilic block copolymer is disclosed. The amphiphilic block copolymer includes one or more hydrophilic polymers, one or more hydrophobic polymer, and one or more zwitterions. The invention also provides a nanoparticle and carrier including the amphiphilic block copolymer for delivery of water insoluble drugs, growth factors, genes, or water insoluble cosmetic substances.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: January 27, 2015
    Assignee: Industrial Technology Research Institute
    Inventors: Ming-Fa Hsieh, Hsuen-Tseng Cha'ng, Chin-Fu Chen, Yuan-Chia Chang, Pei Kan, Tsai-Yu Lin
  • Publication number: 20140186963
    Abstract: The present invention discloses a system for testing microfluid which is made with a disposable disc. The high sensitivity, high sensing accuracy, and quick response microfluidic disc is demonstrated in the present invention. It is note that easy to test microfluid without traditional detecting method, and then reduce energy and simplify procedure. Furthermore, to additive the microfluidic disc is useful to enhance blood typing, and hence raising the sensitivity by the video recognition of blood agglutination.
    Type: Application
    Filed: April 16, 2013
    Publication date: July 3, 2014
    Applicant: CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Ging-Ho Hsiue, Shia-Chung Chen, Wen-Tyng Li, Yaw-Jen Chang, Yung Chang, Yi-Hua Fan, Ming-Fa Hsieh, Wei-Liang Liao, Ching-En Chen, Ching-Wei Huang, Ying-Ming Liang
  • Publication number: 20130149789
    Abstract: A liquid testing system is provided, which includes a distribution module, a testing chip, a driving module and an image analyzing module. The distribution module is for providing a liquid. The testing chip receives the liquid from the distribution module. The driving module is connected to the testing chip and drives the testing chip to rotate, wherein the liquid flowing in the testing chip is actuated by centrifugal force. The image analyzing module produces and analyzes an image of the liquid in the testing chip.
    Type: Application
    Filed: June 6, 2012
    Publication date: June 13, 2013
    Inventors: Ging-Ho Hsiue, Shia-Chung Chen, Yaw-Jen Chang, Yi-Hua Fan, Wen-Tyng Li, Yung Chang, Ming-Fa Hsieh, Ching-Wei Huang, Ying-Ming Liang
  • Patent number: 8124128
    Abstract: An amphiphilic block copolymer. The amphiphilic block copolymer includes one or more hydrophilic polymers, one or more hydrophobic polymer, and one or more zwitterions. The invention also provides a nano particle and carrier comprising the amhpiphilic block copolymer for delivery of water-insoluble drugs, growth factors, genes, or cosmetic substances.
    Type: Grant
    Filed: November 8, 2005
    Date of Patent: February 28, 2012
    Assignee: Industrial Technology Research Institute
    Inventors: Ming-Fa Hsieh, Hsuen-Tseng Chang, Chin-Fu Chen, Yuan-Chia Chang, Pei Kan, Tsai-Yu Lin, Yuan-Hung Hsu
  • Publication number: 20080166382
    Abstract: An amphiphilic block copolymer is disclosed. The amphiphilic block copolymer includes one or more hydrophilic polymers, one or more hydrophobic polymer, and one or more zwitterions. The invention also provides a nanoparticle and carrier including the amphiphilic block copolymer for delivery of water insoluble drugs, growth factors, genes, or water insoluble cosmetic substances.
    Type: Application
    Filed: March 21, 2008
    Publication date: July 10, 2008
    Inventors: Ming-Fa Hsieh, Hsuen-Tseng Chang, Chin-Fu Chen
  • Publication number: 20070104654
    Abstract: An amphiphilic block copolymer. The amphiphilic block copolymer includes one or more hydrophilic polymers, one or more hydrophobic polymer, and one or more zwitterions. The invention also provides a nano particle and carrier comprising the amhpiphilic block copolymer for delivery of water-insoluble drugs, growth factors, genes, or cosmetic substances.
    Type: Application
    Filed: November 8, 2005
    Publication date: May 10, 2007
    Inventors: Ming-Fa Hsieh, Hsuen-Tseng Chang, Chin-Fu Chen, Yuan-Chia Chang, Pei Kan, Tsai-Yu Lin
  • Patent number: 7179867
    Abstract: A thermo-sensitve copolymer of following formula; is disclosed; wherein R1 is hydrogen, or —C(?O)—R2; R2 is C7-30 alkyl substituted or unsubstituted with functional groups; R3 is hydrogen, or C1-6 alkyl; and x, y or z individually is an integer greater than 0. The thermo-sensitive copolymers disclosed here are easy to be implanted into a human body through injection. The biodegradability is greatly improved and the cytotoxicity of the copolymers is low.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: February 20, 2007
    Assignee: Industrial Technology Research Institute
    Inventors: Ken-Yuan Chang, Ming-Hsi Yeh, Ming-Fa Hsieh, Pei Kan, Yu-Yan Jan, Shu-Hua Jan, Xi-Zhang Lin
  • Publication number: 20050113531
    Abstract: A thermo-sensitve copolymer of following formula; is disclosed; wherein R1 is hydrogen, or —C(?O)—R2; R2 is C7-30 alkyl substituted or unsubstituted with functional groups; R3 is hydrogen, or C1-6 alkyl; and x, y or z individually is an integer greater than 0. The thermo-sensitive copolymers disclosed here are easy to be implanted into a human body through injection. The biodegradability is greatly improved and the cytotoxicity of the copolymers is low.
    Type: Application
    Filed: November 26, 2003
    Publication date: May 26, 2005
    Applicant: Industrial Technology Research Institute
    Inventors: Ken-Yuan Chang, Ming-Hsi Yeh, Ming-Fa Hsieh, Pei Kan, Yu-Yan Jan, Shu-Hua Jan, Xi-Zhang Lin
  • Publication number: 20040219175
    Abstract: The present invention relates to a temperature-sensitive thermogelling emulsion system for bioactive substances, consisting of a biodegradable temperature-sensitive aqueous phase polymer solution, and a pharmaceutically acceptable oil phase carrier, which embeds the bioactive substance. The oil phase carrier and the temperature-sensitive polymer solution are mixed mutually to produce the emulsion, and the emulsion is a liquid while the temperature is below the lower critical solution temperature (LCST) and reversibly transforms into a gel while the temperature is above said lower critical solution temperature. The emulsions are able to offer the controlled release without burst effect and afterward in a near zero order manner, as well as be non-invasively monitored post-implantation. The design of entrapment of the bioactive substances in the oily phase is also beneficial to preserve the bioactivity of the environment-sensitive substances.
    Type: Application
    Filed: December 31, 2003
    Publication date: November 4, 2004
    Applicant: Industrial Technology Research Institute
    Inventors: Pei Kan, Xi-Zhang Lin, Ming-Fa Hsieh, Ken-Yuan Chang
  • Patent number: 6001519
    Abstract: An information recording medium including a substrate, an intermediate conductive layer, and a high molecular weight layer. When the high molecular weight layer is heated to close to its glass (transition) temperature by applying an AC field in order to induce thermal motion in molecular electric coupling poles present in the high molecular weight layer, the coupling poles are polarized by an external electric field applied between a microscopic probe tip and the intermediate conductive layer, the polarization becoming fixed when the temperature of the layer drops.
    Type: Grant
    Filed: July 2, 1998
    Date of Patent: December 14, 1999
    Assignee: Industrial Technology Research Institute
    Inventors: Arnold Chang Mou Yang, Yung-Shi Lin, Ming-Fa Hsieh, Shih-Tung Cheng, Min-Chieh Chou