Patents by Inventor Ming Gu

Ming Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030089472
    Abstract: A composition comprising an enzyme exhibiting laccase activity and an enzyme enhancing agent, also referred to as a mediator, is disclosed. A process for oxidizing a substrate that comprises treating the substrate with a composition comprising an enzyme exhibiting laccase activity and an enzyme enhancing agent is disclosed. The process when used on lignin-containing material bleaches the lignin-containing material. A process for enhancing the activity of an enzyme exhibiting laccase activity that comprises adding an enzyme enhancing agent to the enzyme is also disclosed.
    Type: Application
    Filed: December 20, 2001
    Publication date: May 15, 2003
    Inventors: Huai N. Cheng, Simon Delagrave, Qu-Ming Gu, Daniel Michalopoulos, Dennis J. Murphy
  • Publication number: 20030060446
    Abstract: Novel polysaccharides comprising one or more oxime linkages are provided. Methods for their preparation include the polycondensation of saccharides bearing oxime-forming substituents. In some embodiments, polymerization is conducted in the presence of galactose oxidase. The resulting oxime-linked polysaccharides have desirable properties and are useful in numerous applications including paper manufacturing and drug delivery vehicles.
    Type: Application
    Filed: September 18, 2001
    Publication date: March 27, 2003
    Inventors: Peng George Wang, Wenhua Xie, Lei Qiao, Huai N. Cheng, Dennis J. Murphy, Qu-Ming Gu
  • Publication number: 20030047295
    Abstract: A process of oxidizing a substrate is disclosed. The process comprising the step of treating the substrate with an oxidizing enzyme, a mediator that enhances the oxidative activity of the enzyme, and a chain transfer agent. In one example, the substrate is a lignin-containing material and the process results in bleaching of the lignin-containing material. Examples of some useful enzymes are laccase, catechol oxidase, monophenol monooxygenase, and bilirubin oxidase. A composition comprising an oxidative enzyme, a mediator that enhances the oxidative activity of the enzyme, and a chain transfer agent is also disclosed.
    Type: Application
    Filed: December 20, 2001
    Publication date: March 13, 2003
    Inventors: Huai N. Cheng, Simon Delagrave, Qu-Ming Gu, Dennis J. Murphy
  • Patent number: 6528643
    Abstract: Product of esterified polysaccharides and the process of making such product. The process can be enzymatic where an enzyme is used as a catalyst for the reaction. The process can also be chemical where no enzyme is used. Novel products are obtained through lipase-catalyzed &bgr;-lactone ring opening alcoholysis of ketene dimers and the process of making such compositions containing products.
    Type: Grant
    Filed: May 5, 2000
    Date of Patent: March 4, 2003
    Assignee: Hercules Incorporated
    Inventors: Huai N. Cheng, Qu Ming Gu
  • Patent number: 6527915
    Abstract: Methods for inhibiting the depositions of organic contaminants from pulp in pulp and papermaking systems are disclosed. Whey proteins are added to the pulp or applied to deposition prone surfaces of a papermaking system.
    Type: Grant
    Filed: March 22, 2001
    Date of Patent: March 4, 2003
    Assignee: Hercules Incorporated
    Inventor: Qu-Ming Gu
  • Patent number: 6461477
    Abstract: Methods for inhibiting the depositions of organic contaminants from pulp in pulp and papermaking systems are disclosed. A combination of a protein and a cationic polymer is added to the pulp or applied to deposition prone surfaces of a papermaking system.
    Type: Grant
    Filed: March 22, 2001
    Date of Patent: October 8, 2002
    Assignee: Hercules Incorporated
    Inventors: Duy T. Nguyen, Qu-Ming Gu
  • Publication number: 20020123624
    Abstract: A hydrophobically esterified starch, is disclosed, having the general formula: 1
    Type: Application
    Filed: February 23, 2001
    Publication date: September 5, 2002
    Inventors: Lei Qiao, Qu-Ming Gu, H. N. Cheng
  • Publication number: 20020106747
    Abstract: Esterified polysaccharides and the process of making such products are disclosed. The process can be enzymatic where an enzyme is used as a catalyst for the reaction. The process can also be chemical where no enzyme is used. Novel Products are obtained through lipase-catalyzed &bgr;-lactone ring opening alcoholysis of ketene dimers and the process of making such compositions containing products.
    Type: Application
    Filed: February 6, 2002
    Publication date: August 8, 2002
    Inventors: H. N. Cheng, Qu Ming Gu
  • Publication number: 20020096293
    Abstract: Methods for inhibiting the depositions of organic contaminants from pulp in pulp and papermaking systems are disclosed. A combination of a protein and a cationic polymer is added to the pulp or applied to deposition prone surfaces of a papermaking system.
    Type: Application
    Filed: March 22, 2001
    Publication date: July 25, 2002
    Inventors: Duy T. Nguyen, Qu-Ming Gu
  • Publication number: 20010050150
    Abstract: Methods for inhibiting the depositions of organic contaminants from pulp in pulp and papermaking systems are disclosed. Whey proteins are added to the pulp or applied to deposition prone surfaces of a papermaking system.
    Type: Application
    Filed: March 22, 2001
    Publication date: December 13, 2001
    Inventor: Qu-Ming Gu
  • Patent number: 6206764
    Abstract: The present invention provides a method for machining hard materials using the machining fluids containing long chain alcohol in which the machining fluid is applied to a machining tool and then lubricates the machining of the workpiece by the machining tool and protects the machining tool during machining. The method is particularly useful when used with machining tools having a Mohs hardness of at least 9 and is most particularly useful when used with diamond machining tools.
    Type: Grant
    Filed: April 16, 1998
    Date of Patent: March 27, 2001
    Assignee: The United States of America as represented by the Secretary of Commerce
    Inventors: Stephen Hsu, Tsi-Neng Ying, Jia-Ming Gu, Yu-Shu Wang, Richard S. Gates
  • Patent number: 6200751
    Abstract: The promoter of the EPCR gene has been isolated from both murine (SEQ. ID No. 1) and human (SEQ. ID No. 2) genomic libraries. The promoter includes a region (nucleotides 3130 to 3350 of SEQ. ID No. 1 which affects selective gene expression in endothelial cells), and a region (nucleotides 2270 to 2840 of SEQ. ID No. 1) which affects selective gene expression in large vessel endothelial cells, as compared to expression in all endothelial cells. The EPCR promoter contains a thrombin responsive element, CCCACCCC (SEQ. ID No. 3), (murine, nucleotides 3007 to 3014 SEQ. ID No. 1 and human, nucleotides 2722 to 2729 SEQ. ID No. 2). The EPCR also contains a serum response element (nucleotides 2990 to 3061 of SEQ. ID No. 1). The regulatory sequences present in the EPCR promoter can be used for thrombin or serum controlled recombinant gene expression specific to either all endothelial cells or primarily endothelial cells of large vessels.
    Type: Grant
    Filed: November 7, 1997
    Date of Patent: March 13, 2001
    Assignee: Oklahoma Medical Research Foundation
    Inventors: Jian-Ming Gu, Charles T. Esmon
  • Patent number: 6159721
    Abstract: Amine modified pectins wherein the amine is a water soluble amine, amino acid, etc. and process to catalyze the reaction of water soluble polymers having alkoxyester and carboxylic acid functionality, such as polysaccharides, with a primary or secondary amine in the presence of a protease and water.
    Type: Grant
    Filed: August 20, 1997
    Date of Patent: December 12, 2000
    Assignee: Hercules Incorporated
    Inventors: Huai Nan Cheng, Qu-Ming Gu, Robert G. Nickol
  • Patent number: 5717113
    Abstract: Novel acetogenins isolated from Asimina triloba and Goniothalamus giganteus of the family Annonaceae and derivatives of those and other acetogenins are described. Bioactive cyclic formaldehyde acetal derivatives are prepared from Annonaceous acetogenins having 1,2-, 1,4- or 1,5-diols. A non-adjacent bis-tetrahydrofuran (THF) acetogenin is prepared from an unsaturated mono-THF acetogenin earlier isolated from Goniothalamus giganteus. The substantially pure acetogenins and acetogenin derivatives of the invention exhibit cytotoxicity to human solid tumor cell lines equipotent to adriamycin or orders of magnitude more potent than adriamycin, and they exhibit effective pesticidal activities.
    Type: Grant
    Filed: July 12, 1996
    Date of Patent: February 10, 1998
    Assignee: Purdue Research Foundation
    Inventors: Jerry L. McLaughlin, Zhe-ming Gu, Geng-xian Zhao
  • Patent number: 5633086
    Abstract: For titanium and titanium alloys in tribological applications under bound lubrication conditions, there are employed epoxy coatings adhered to the surface of the titanium or titanium alloy by a titanium oxide primer layer. The anti-wear properties of the epoxy coating can be improved by incorporation of an anti-wear filler such as diamond powder. These coatings improve the friction coefficient and anti-wear properties of the titanium and titanium alloys.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: May 27, 1997
    Assignee: The United States of America as represented by the Secretary of Commerce
    Inventors: Stephen M. Hsu, Jia-Ming Gu
  • Patent number: 5536848
    Abstract: Novel acetogenins isolated from Asimina triloba and Goniothalamus giganteus of the family Annonaceae and derivatives of those and other acetogenins are described. Bioactive cyclic formaldehyde acetal derivatives are prepared from Annonaceous acetogenins having 1,2-, 1,4- or 1,5-diols. A non-adjacent bis-tetrahydrofuran(THF) acetogenin is prepared from an unsaturated mono-THF acetogenin earlier isolated from Goniothalamus giganteus. The substantially pure acetogenins and acetogenin derivatives of the invention exhibit cytotoxicity to human solid tumor cell lines equipotent to adriamycin or orders of magnitude more potent than adriamycin, and they exhibit effective pesticidal activities.
    Type: Grant
    Filed: June 14, 1994
    Date of Patent: July 16, 1996
    Assignee: Purdue Research Foundation
    Inventors: Jerry L. McLaughlin, Zhe-ming Gu, Geng-xian Zhao