Patents by Inventor Ming Hsin Chuang
Ming Hsin Chuang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240124844Abstract: The present disclosure provides a method for preparing a composition including mesenchymal stem cells, extracellular vesicles produced by the mesenchymal stem cells, and growth factors, the composition prepared by the method, and use of the composition for treating arthritis. The composition of the present disclosure achieves the effect of treating arthritis through various efficacy experiments.Type: ApplicationFiled: October 4, 2023Publication date: April 18, 2024Inventors: Chia-Hsin Lee, Po-Cheng Lin, Yong-Cheng Kao, Ming-Hsi Chuang, Chun-Hung Chen, Chao-Liang Chang, Kai-Ling Zhang
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Publication number: 20240115616Abstract: The present disclosure provides a method for treating liver cirrhosis by using a composition including mesenchymal stem cells, extracellular vesicles produced by the mesenchymal stem cells, and growth factors. The composition of the present disclosure achieves the effect of treating liver cirrhosis through various efficacy experiments.Type: ApplicationFiled: October 4, 2023Publication date: April 11, 2024Inventors: Po-Cheng Lin, Pi-Chun Huang, Zih-Han Hong, Ming-Hsi Chuang, Yi-Chun Lin, Chia-Hsin Lee, Chun-Hung Chen, Chao-Liang Chang, Kai-Ling Zhang
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Publication number: 20240117314Abstract: The present invention relates to a method for preparing a modified stem cell, including the following steps: a cell culture step: culturing stem cells in a first culture medium of a culture dish at a predetermined cell density, and removing the first culture medium after a first culture time to obtain a first cell intermediate; an activity stimulation step: preserving the first cell intermediate in a freezing container having a cell cryopreservation solution, and performing a constant temperature stimulation treatment or a variable temperature stimulation treatment for at least more than 1 day; and a product collection step: after completing the activity stimulation step, placing the freezing container in an environment at a thawing temperature for thawing, and then removing the cell cryopreservation solution to obtain the modified stem cell. The modified stem cell can release at least one or more of IL-4, IL-5, IL-13, G-CSF, Fractalkine, and EGF.Type: ApplicationFiled: October 3, 2023Publication date: April 11, 2024Inventors: Ruei-Yue Liang, Chia-Hsin Lee, Kai-Ling Zhang, Po-Cheng Lin, Ming-Hsi Chuang, Yu-Chen Tsai, Peggy Leh Jiunn Wong
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Patent number: 11927796Abstract: A display device includes a frame body, a positioning unit, a light guide plate, and an elastic unit. The frame body includes a back plat which includes a limiting slot. The positioning includes a loading portion, a side wall portion, and a positioning protrusion. The positioning protrusion is located on the loading portion and extends toward the back plate to fit in the limiting slot. When the elastic unit is in the non-compressed state, one end of the elastic unit abuts against the side wall plate, and the other end abuts against the side wall portion so that the positioning protrusion is at a first position of the limiting slot. When the light guide plate is heated, the positioning protrusion is driven to move to a second position of the limiting slot, and the elastic unit is pressed to be in the compressed state.Type: GrantFiled: March 2, 2023Date of Patent: March 12, 2024Assignee: AUO DISPLAY PLUS CORPORATIONInventor: Ming-Hsin Chuang
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Publication number: 20240075071Abstract: Disclosed in the present invention is an optimized cell transplant. The optimized cell transplant is formed by performing gene induction and modification on a mesenchymal stem cell in the form of a small molecule and protein composition. The expression levels of CD200 gene, Galectin-9 gene and VISTA gene can be increased synchronously after cell culture. Vector virus infection and plasmid transfection are not required in the cell preparation process, so that high biological safety and great clinical application value of cells are achieved.Type: ApplicationFiled: November 23, 2022Publication date: March 7, 2024Inventors: Ruei-Yue Liang, Kai-Ling Zhang, Ming-Hsi Chuang, Po-Cheng Lin, Peggy Leh Jiunn Wong, Chia-Hsin Lee
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Patent number: 8728407Abstract: A holding device disposed in a bio-detecting instrument for holding a test strip is provided, wherein the holding device comprises a first casing, a second casing, an ejecting member, and an elastic member. The second casing is assembled with the first casing to form an accommodating space, wherein the sensing terminals are extended into the accommodating space. The ejecting member comprises a push rod configured to be reciprocated in the accommodating space. The elastic member is configured to be compressed by driving the ejecting member to an ejecting position, where the push rod enters the accommodating space and is adapted to push the test strip outward without being contact with the sensing terminals, and the elastic member is configured to be released by drawing the push rod back from the accommodating space to an initial position.Type: GrantFiled: September 15, 2012Date of Patent: May 20, 2014Assignee: Apex Biotechnology Corp.Inventors: Ming-Chang Hsu, Ming-Hsin Chuang, Mon-Wen Yang, Thomas Y. S. Shen
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Patent number: 8524168Abstract: A device for holding a medical test strip is provided. The device comprises a receiving casing having an opening for receiving the medical test strip and a first stopping portion protruding from an upper surface of the receiving casing; an ejection base having a cover and a pusher beneath the cover, the cover downwardly extending a second stopping portion for sliding against the upper surface of the receiving casing; and an elastic member located between the receiving casing and the ejection base. When the pusher moves toward the opening by an external force to eject the test strip from the opening, the elastic member is compressed and the second stopping portion slides away from the first stopping portion. When the external force disappears, the second stopping portion slides toward the first stopping portion by a resilient force of the elastic member until the first stopping portion and the second stopping portion are engaged.Type: GrantFiled: June 15, 2010Date of Patent: September 3, 2013Assignee: Apex Biotechnology Corp.Inventors: Ming-Chang Hsu, Mon Wen Yang, Ming-Hsin Chuang, Thomas Y. S. Shen
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Publication number: 20130121875Abstract: A holding device disposed in a bio-detecting instrument for holding a test strip is provided, wherein the holding device comprises a first casing, a second casing, an ejecting member, and an elastic member. The second casing is assembled with the first casing to form an accommodating space, wherein the sensing terminals are extended into the accommodating space. The ejecting member comprises a push rod configured to be reciprocated in the accommodating space. The elastic member is configured to be compressed by driving the ejecting member to an ejecting position, where the push rod enters the accommodating space and is adapted to push the test strip outward without being contact with the sensing terminals, and the elastic member is configured to be released by drawing the push rod back from the accommodating space to an initial position.Type: ApplicationFiled: September 15, 2012Publication date: May 16, 2013Applicant: APEX BIOTECHNOLOGY CORP.Inventors: Ming-Chang Hsu, Ming-Hsin Chuang, Mon-Wen Yang, Thomas Y.S. Shen
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Patent number: 8382054Abstract: A holding device comprises a first accommodation portion, a second accommodation portion, an elastic portion, and an actuating portion. The elastic portion includes a first end contacting the first accommodation portion and a second end contacting the actuating portion. The first accommodation portion includes at least one aperture. The second accommodation portion includes at least one connecting part, which passes through the aperture and connects with the actuating portion. When the actuating portion is pressed toward the first accommodation portion, a space between the first accommodation portion and the second accommodation portion expands.Type: GrantFiled: April 20, 2011Date of Patent: February 26, 2013Assignee: Apex Biotechnology Corp.Inventors: Ming Chang Hsu, Ming Hsin Chuang, Mon Wen Yang, Thomas Y. S. Shen
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Publication number: 20120126082Abstract: A holding device comprises a first accommodation portion, a second accommodation portion, an elastic portion, and an actuating portion. The elastic portion includes a first end contacting the first accommodation portion and a second end contacting the actuating portion. The first accommodation portion includes at least one aperture. The second accommodation portion includes at least one connecting part, which passes through the aperture and connects with the actuating portion. When the actuating portion is pressed toward the first accommodation portion, a space between the first accommodation portion and the second accommodation portion expands.Type: ApplicationFiled: April 20, 2011Publication date: May 24, 2012Applicant: APEX BIOTECHNOLOGY CORP.Inventors: MING CHANG HSU, MING HSIN CHUANG, MON WEN YANG, THOMAS Y.S. SHEN
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Publication number: 20100319170Abstract: A device for holding a medical test strip is provided. The device comprises a receiving casing having an opening for receiving the medical test strip and a first stopping portion protruding from an upper surface of the receiving casing; an ejection base having a cover and a pusher beneath the cover, the cover downwardly extending a second stopping portion for sliding against the upper surface of the receiving casing; and an elastic member located between the receiving casing and the ejection base. When the pusher moves toward the opening by an external force to eject the test strip from the opening, the elastic member is compressed and the second stopping portion slides away from the first stopping portion. When the external force disappears, the second stopping portion slides toward the first stopping portion by a resilient force of the elastic member until the first stopping portion and the second stopping portion are engaged.Type: ApplicationFiled: June 15, 2010Publication date: December 23, 2010Applicant: APEX BIOTECHNOLOGY CORPInventors: Ming-Chang Hsu, Mon Wen Yang, Ming-Hsin Chuang, Thomas Y.S. Shen