Abstract: An endoscope device, an endoscopic medical assistance system and an endoscopic image processing method are provided. An endoscope in the endoscope device and the endoscopic medical assistance system senses light beams reflected by an object to generate initial images. After the initial images are aligned with each other to form a superimposed image, an image fusion device of the endoscopic medical assistance system analyzes features of the superimposed image to convert the superimposed image into a feature image. The image fusion device adjusts a color depth of each of a plurality of pixel points of the feature image according to a relationship between the color depth of each of the pixel points and a maximum color depth that are classified in the same color tone in each of pixel regions of the feature image. The image fusion device generates a fusion image according to the adjusted feature image.