Patents by Inventor Ming-ju Chen

Ming-ju Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240139301
    Abstract: The disclosure provides a method of active immunotherapy for a cancer patient, comprising administering vaccines against Globo series antigens (i.e., Globo H, SSEA-3 and SSEA-4). Specifically, the method comprises administering Globo H-CRM197 (OBI-833/821) in patients with cancer. The disclosure also provides a method of selecting a cancer patient who is suitable as treatment candidate for immunotherapy. Exemplary immune response can be characterized by reduction of the severity of disease, including but not limited to, prevention of disease, delay in onset of disease, decreased severity of symptoms, decreased morbidity and delayed mortality.
    Type: Application
    Filed: November 19, 2021
    Publication date: May 2, 2024
    Inventors: Ming-Tain LAI, Cheng-Der Tony YU, I-Ju CHEN, Wei-Han LEE, Chueh-Hao YANG, Chun-Yen TSAO, Chang-Lin HSIEH, Chien-Chih OU, Chen-En TSAI
  • Patent number: 11942436
    Abstract: A method of forming a semiconductor device includes: forming first electrical components in a substrate in a first device region of the semiconductor device; forming a first interconnect structure over and electrically coupled to the first electrical components; forming a first passivation layer over the first interconnect structure, the first passivation layer extending from the first device region to a scribe line region adjacent to the first device region; after forming the first passivation layer, removing the first passivation layer from the scribe line region while keeping a remaining portion of the first passivation layer in the first device region; and dicing along the scribe line region after removing the first passivation layer.
    Type: Grant
    Filed: August 9, 2022
    Date of Patent: March 26, 2024
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Hsien-Wei Chen, Ying-Ju Chen, Ming-Fa Chen
  • Publication number: 20240058400
    Abstract: An isolated bacterial strain of Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 deposited under the DSMZ Accession No. DSM 34213 is provided; a probiotic composition including an Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 and optionally, one or more additional probiotic organisms that enhance the probiotic activity of the Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 is also provided; and a method for preventing or treating chronic kidney disease in a subject in need thereof including: administering to the subject a pharmaceutically effective amount of the probiotic composition including an isolated bacterial strain of Lactiplantibacillus plantarum subsp. plantarum MFM 30-3, and optionally, one or more additional probiotic organisms that enhance the probiotic activity of the Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 is further provided.
    Type: Application
    Filed: November 6, 2023
    Publication date: February 22, 2024
    Applicant: National Taiwan University
    Inventors: Ming-Ju Chen, Hsiao-Wen Huang
  • Publication number: 20230161122
    Abstract: A silicon photonics optical transceiver device includes a silicon photonics optical module and a heat conducting housing that accommodates the silicon photonic optical module therein. The heat conducting housing has an inner surface formed with a first heat dissipation portion that wraps around and is in contact with transmitter optical sub-assemblies of the silicon photonics optical module to realize thermal conduction, and a second heat dissipation portion that is in contact with a digital signal processor of the silicon photonics optical module to realize thermal conduction.
    Type: Application
    Filed: July 8, 2022
    Publication date: May 25, 2023
    Inventors: Ming-Ju Chen, Shih-Jhih Yang, Hua-Hsin Su, Wan-Pao Peng, Wen-Hsien Lee, Peng-Kai Hsu, Chung-Ho Wang
  • Publication number: 20220249580
    Abstract: The present invention relates to an isolated bacterial strain of Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 deposited at Food Industry Research and Development Institute, Taiwan, under accession number BCRC 911035. The present invention also relates to a probiotic composition comprising an isolated bacterial strain of Lactiplantibacillus plantarum subsp. plantarum MFM 30-3 deposited at Food Industry Research and Development Institute, Taiwan, under accession number BCRC 911035, and optionally, one or more additional probiotic organisms that enhance the probiotic activity of the Lactiplantibacillus plantarum subsp. plantarum MFM 30-3. The present invention further relates to a method for preventing or treating chronic kidney disease in a subject in need thereof comprising: administering to said subject a pharmaceutically effective amount of the probiotic composition comprising an isolated bacterial strain of Lactiplantibacillus plantarum subsp.
    Type: Application
    Filed: February 4, 2022
    Publication date: August 11, 2022
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Ming-Ju Chen, Hsiao-Wen Huang
  • Patent number: 11409062
    Abstract: Provided is an optical transceiver module, comprising a housing, a substrate, an optical receiving device and a plurality of optical transmitting devices. The substrate is disposed in the housing. The optical receiving device is disposed on the substrate. The plurality of optical transmitting devices are connected to the substrate, and the optical transmitting devices are arranged in an alternating manner. The optical transceiver module effectively utilizes the internal space thereof for a compact design and can have a simple structure for manufacturing.
    Type: Grant
    Filed: February 9, 2021
    Date of Patent: August 9, 2022
    Assignee: USENLIGHT CORPORATION
    Inventors: Chun-Yang Chang, Yun-Cheng Huang, Wen-Hsien Li, Cheng-Hung Lu, Ming-Ju Chen, Chang-Cherng Wu
  • Patent number: 11347010
    Abstract: Provided is an optical cable module, comprising an optical fiber cable, and an optical transceiver module. The optical transceiver module comprises a substrate; at least one optical transmitting device connected to the substrate; a plurality of optical receiving devices connected to the substrate, wherein the optical receiving devices are cylindrical optical receiving devices, and an air tightness of each of the cylindrical optical receiving devices is in a range of 1×10-12 atm*cc/sec to 5*10-7 atm*cc/sec; at least one optical receiving holder configured to assemble the optical receiving devices, wherein the optical receiving devices are secured in the optical receiving holder.
    Type: Grant
    Filed: February 9, 2021
    Date of Patent: May 31, 2022
    Assignee: USENLIGHT CORPORATION
    Inventors: Chun-Yang Chang, Yun-Cheng Huang, Wen-Hsien Li, Cheng-Hung Lu, Ming-Ju Chen, Chang-Cherng Wu
  • Patent number: 11105990
    Abstract: The present invention is to provide an optical transceiver module comprising a housing, a substrate, an optical receiving device and a plurality of optical transmitting devices. The substrate is disposed in the housing. The optical receiving device is disposed on the substrate. The plurality of optical transmitting devices are connected to the substrate, and there is a tilt angle between the optical transmitting devices and the substrate.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: August 31, 2021
    Assignee: USENLIGHT CORPORATION
    Inventors: Chun-Yang Chang, Yun-Cheng Huang, Wen-Hsien Li, Cheng-Hung Lu, Ming-Ju Chen, Chang-Cherng Wu
  • Publication number: 20210165176
    Abstract: Provided is an optical cable module, comprising an optical fiber cable, and an optical transceiver module. The optical transceiver module comprises a substrate; at least one optical transmitting device connected to the substrate; a plurality of optical receiving devices connected to the substrate, wherein the optical receiving devices are cylindrical optical receiving devices, and an air tightness of each of the cylindrical optical receiving devices is in a range of 1×10-12 atm*cc/sec to 5*10-7 atm*cc/sec; at least one optical receiving holder configured to assemble the optical receiving devices, wherein the optical receiving devices are secured in the optical receiving holder.
    Type: Application
    Filed: February 9, 2021
    Publication date: June 3, 2021
    Inventors: Chun-Yang CHANG, Yun-Cheng HUANG, Wen-Hsien LI, Cheng-Hung LU, Ming-Ju CHEN, Chang-Cherng WU
  • Publication number: 20210165177
    Abstract: Provided is an optical transceiver module, comprising a housing, a substrate, an optical receiving device and a plurality of optical transmitting devices. The substrate is disposed in the housing. The optical receiving device is disposed on the substrate. The plurality of optical transmitting devices are connected to the substrate, and the optical transmitting devices are arranged in an alternating manner. The optical transceiver module effectively utilizes the internal space thereof for a compact design and can have a simple structure for manufacturing.
    Type: Application
    Filed: February 9, 2021
    Publication date: June 3, 2021
    Inventors: Chun-Yang CHANG, Yun-Cheng HUANG, Wen-Hsien LI, Cheng-Hung LU, Ming-Ju CHEN, Chang-Cherng WU
  • Publication number: 20200301083
    Abstract: The present invention is to provide an optical transceiver module comprising a housing, a substrate, an optical receiving device and a plurality of optical transmitting devices. The substrate is disposed in the housing. The optical receiving device is disposed on the substrate. The plurality of optical transmitting devices are connected to the substrate, and there is a tilt angle between the optical transmitting devices and the substrate.
    Type: Application
    Filed: March 6, 2020
    Publication date: September 24, 2020
    Inventors: Chun-Yang CHANG, Yun-Cheng HUANG, Wen-Hsien LI, Cheng-Hung LU, Ming-Ju CHEN, Chang-Cherng WU
  • Patent number: 10184490
    Abstract: A noise reduction diffuser for an electric blower has a motor holder and a rear cover fitted to the motor holder. The motor holder includes a sidewall and a bottom portion at one end of the sidewall. The other end of the sidewall has an opening for mounting an electric motor inside the sidewall. An output shaft of the motor extends through the bottom portion for driving a fan. The motor holder and the rear cover form a Helmholtz resonance cavity.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: January 22, 2019
    Assignee: JOHNSON ELECTRIC S.A.
    Inventors: Chuan Hui Fang, Ming Ju Chen, Hong Guang Li
  • Patent number: 9884079
    Abstract: A Lactobacillus mali strain that can be used for treating a metabolic syndrome is provided. A method for treating obesity, diabetes or a complication of diabetes by using the Lactobacillus mali strain is also provided.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: February 6, 2018
    Assignee: National Taiwan University
    Inventors: Ming-Ju Chen, Yu-Chun Lin, Hsin-Hui Hsieh
  • Publication number: 20170159669
    Abstract: An impeller, and a pump and a fluid delivery device using the pump are disclosed. An impeller includes an base plate and a plurality of long blades and a plurality of short blades disposed on the base plate. The impeller further includes a shaft mounting portion disposed on the base plate. The plurality of long blades and the plurality of short blades are alternatively arranged on the base plate and surround the shaft mounting portion. The long blades and the short blades are all arcuate blades. The above fluid delivery device, the pump and the impeller have improved efficiency.
    Type: Application
    Filed: December 5, 2016
    Publication date: June 8, 2017
    Inventors: Chuan Hui FANG, Feng XUE, Ming Ju CHEN, Feng LIU
  • Publication number: 20170035814
    Abstract: A new Lactobacillus mali that can be used for preventing or treating a metabolic syndrome is provided. A method for preventing or treating obesity, diabetes or a complication of diabetes by using the Lactobacillus mali is also provided.
    Type: Application
    Filed: December 21, 2015
    Publication date: February 9, 2017
    Applicant: National Taiwan University
    Inventors: Ming-Ju Chen, Yu-Chun Lin, Hsin-Hui Hsieh
  • Publication number: 20160238033
    Abstract: A noise reduction diffuser for an electric blower has a motor holder and a rear cover fitted to the motor holder. The motor holder includes a sidewall and a bottom portion at one end of the sidewall. The other end of the sidewall has an opening for mounting an electric motor inside the sidewall. An output shaft of the motor extends through the bottom portion for driving a fan. The motor holder and the rear cover form a Helmholtz resonance cavity.
    Type: Application
    Filed: February 12, 2016
    Publication date: August 18, 2016
    Inventors: Chuan Hui FANG, Ming Ju CHEN, Hong Guang LI
  • Publication number: 20140193367
    Abstract: The invention relates to a probiotic composition for reducing uremic toxins and the manufacturing method thereof. The probiotic composition comprises at least one selected from the group consisting of: Lactobacillus plantarum BCRC 12251, Lactobacillus paracasei BCRC 12188, Streptococcus thermophilus BCRC 13869 and pharmaceutically acceptable vehicles, excipients, diluents, adjuvants, etc. The invention further relates to a probiotic composition consisted of Lactobacillus plantarum BCRC 12251, Lactobacillus paracasei BCRC 12188, Streptococcus thermophilus BCRC 13869 and pharmaceutically acceptable vehicles, excipients, diluents, adjuvants, etc. In addition, the invention relates to a novel use of the probiotic composition for reducing uremic toxins, wherein the uremic toxins are protein-bound uremic toxins.
    Type: Application
    Filed: March 15, 2013
    Publication date: July 10, 2014
    Applicants: NATIONAL TAIWAN UNIVERSITY, CONMED PHARMACEUTICAL & BIO-MEDICAL CORPORATION
    Inventors: Chen-Yu Fang, Bao-Ji Chen, Ming-Ju Chen, Je-Ruei Liu
  • Publication number: 20130170995
    Abstract: An axial flow fan blade structure and an axial flow fan thereof. The axial flow fan blade structure includes a fan impeller and an annular body. The fan impeller has a hub and multiple blades. Each blade has a first flow guide face and a second flow guide face opposite to the first flow guide face. The annular body is disposed on the blades. The annular body outward extends from the first and second flow guide faces and is annularly connected with the blades along the blades. The annular body not only is able to increase the strength of the blades of the axial flow fan, but also is able to reduce vibration and noise made by the axial flow fan.
    Type: Application
    Filed: January 4, 2012
    Publication date: July 4, 2013
    Inventor: Ming-ju Chen
  • Patent number: 8057173
    Abstract: A single-bearing fan structure includes a fan frame having a bearing cup with a bearing received therein, the bearing cup having a radially inward protruded lip portion formed at a first end to abut on a top of the bearing, and a groove internally formed at a second end; a blade hub having a rotary shaft fixedly connected thereto with a distal end of the rotary shaft inserted into the bearing; a retainer engaged with the groove; a first elastic element fitted around the rotary shaft and located between the blade hub and the bearing; and a second elastic element received in the bearing cup and located between the bearing and the retainer. The first and second elastic elements and the bearing respectively axially and radially support the blade hub, enabling the fan structure to operate stably and have extended service life.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: November 15, 2011
    Assignee: Asia Vital Components ( Shen Zhen) Co., Ltd.
    Inventor: Ming-ju Chen
  • Publication number: 20100266402
    Abstract: A single-bearing fan structure includes a fan frame having a bearing cup with a bearing received therein, the bearing cup having a radially inward protruded lip portion formed at a first end to abut on a top of the bearing, and a groove internally formed at a second end; a blade hub having a rotary shaft fixedly connected thereto with a distal end of the rotary shaft inserted into the bearing; a retainer engaged with the groove; a first elastic element fitted around the rotary shaft and located between the blade hub and the bearing; and a second elastic element received in the bearing cup and located between the bearing and the retainer. The first and second elastic elements and the bearing respectively axially and radially support the blade hub, enabling the fan structure to operate stably and have extended service life.
    Type: Application
    Filed: April 20, 2009
    Publication date: October 21, 2010
    Inventor: Ming-ju Chen