Patents by Inventor Ming-Kuan Chyan

Ming-Kuan Chyan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REAGENTS AND METHODS FOR LABELING MOLECULES WITH ASTATINE ISOTOPES IN HIGHER OXIDATION STATES
    Publication number: 20220354974
    Abstract: Reagents and methods for labeling biomolecules with astatine isotopes in higher oxidation states. The reagents and methods allow for efficient labeling of biomolecules, such as antibodies, without the formation of high molecular weight by products that arise due to 211At-promoted dimerization and higher aggregation of the conjugated biomolecules, and diminish cellular retention of astatine caused by cellular oxidization of the bonded astatine atom in vivo.
    Type: Application
    Filed: April 26, 2022
    Publication date: November 10, 2022
    Applicant: University of Washington
    Inventors: D. Scott Wilbur, Ming-Kuan Chyan, Donald K. Hamlin
  • PROCESS FOR ISOLATION AND PURIFICATION OF ASTATINE-211
    Publication number: 20160053345
    Abstract: This disclosure relates to methods for purifying and isolating astatine-211 from bismuth metal. Also disclosed are automated methods for purifying and isolating astatine-211 from bismuth metal.
    Type: Application
    Filed: August 21, 2015
    Publication date: February 25, 2016
    Inventors: D. Scott Wilbur, Ming-Kuan Chyan, Donald K. Hamlin, Katherine Gagnon, Shigeki Watanabe