Abstract: 1, 2, 4, 5-tetraoxane compounds and derivatives thereof that have anticancer properties are disclosed. Pharmaceutical compositions and pharmaceutical formulations in unit dosage form suitable for the delivery of the compounds to a subject in need thereof are disclosed. The pharmaceutical compositions or formulations may include one or more active agents in addition to the compounds, such as one or more additional anticancer agents. Methods for treating a cancer, reducing a cancer, or treating or ameliorating one or more symptoms associated with a cancer in a subject are also disclosed. The methods include (i) administering to a subject in need thereof an effective amount of the compound (s). The compound (s) can be administered by oral administration, parenteral administration, inhalation, mucosal administration, or a combination thereof. The compound can selectively kill cancer cells and/or cancer stem cells over non-cancerous cells by triggering ferroptosis in the cancer cells and/or cancer stem cells.

Abstract: The present disclosure relates to a car type model comprising an inner structure formed of a metal, a chassis formed of a resin and a wheel axle formed of a metal. The chassis is attached to the inner structure, and the wheel axle is arranged between the chassis and the inner structure. The inner structure and the chassis are configured to keep the wheel axle in a position.

Abstract: The present disclosure relates to a method of manufacturing a model car body, including preparing a steel mold comprising a core plate with an inner core, a top plate and at least two side plates; attaching at least one pre-fabricated plastic block to a side of the inner core of the core plate; combining the core plate, the top plate and the at least two side plates with each other, wherein a cavity is formed among the top plate, the side plates, the inner core of the core plate and the at least one pre-fabricated plastic block; injecting melted plastic material into the cavity, wherein the melted plastic material is filled with the cavity and the at least one pre-fabricated plastic block is encased by the melted plastic material; solidifying the melted plastic so as to form the model car body, wherein the at least one pre-fabricated plastic block is integrated with the plastic model car body; separating the core plate, the top plate and the at least two side plates from each other; and releasing the model ca

Abstract: The present disclosure relates to a car type model comprising an inner structure formed of a metal, a chassis formed of a resin and a wheel axle formed of a metal. The chassis is attached to the inner structure, and the wheel axle is arranged between the chassis and the inner structure. The inner structure and the chassis are configured to keep the wheel axle in a position.

Abstract: The present subject matter is directed to water disinfection by pulsed electric field (PEF) systems. The present subject matter relates to a pulsed electric field assembly with a separator that separates and disinfects the microorganisms in drinking water. The present subject matter relates to an anti-corrosion electrode, particularly an electrode having a zeolite coating layer serving as a protector, a process for the preparation a zeolite coating on a conducting electrode substrate, and application of the zeolite coated electrode on water electrolysis and PEF systems.

Abstract: The present disclosure relates to a hinge mechanism for a door of a model car, including: a pivot element made of metal, wherein the pivot element has a pivot axis and a base that could be mounted to a body of the model car; a lever arm made of metal, wherein the lever arm could be mounted to an inner surface of the door of the model car, and wherein the lever arm has at least one slot configured to receive the pivot axis of the pivot element; and a tension plate made of metal, wherein the tension plate is mounted to the lever arm and configured to press the pivot axis of the pivot element into the at least one slot of the lever arm.

Abstract: The present disclosure relates to a micro-mini pulsed electric field (PEF) device for point-of-use disinfection of drinking water. The pulsed electric field device comprises micro-engineered electrodes and a low-voltage pulsed electric field generator circuit. A pulsed electric field is generated across a micro-gap between the electrodes to achieve disinfection of drinking water.

Abstract: Transdermal patches and devices for delivery of therapeutic drug and/or cosmetic formulations through an intact or porated skin barrier are described. Active-infusion delivers controlled dosing over a period of time to provide long-term efficacy. Methods and devices for preparing active-infusion patches for controlled dose delivery by nonelectronic devices and methods of skin poration that is safe and painless are described.

Abstract: The present disclosure relates to a hinge mechanism for a door of a model car, including: a pivot element made of metal, wherein the pivot element has a pivot axis and a base that could be mounted to a body of the model car; a lever arm made of metal, wherein the lever arm could be mounted to an inner surface of the door of the model car, and wherein the lever arm has at least one slot configured to receive the pivot axis of the pivot element; and a tension plate made of metal, wherein the tension plate is mounted to the lever arm and configured to press the pivot axis of the pivot element into the at least one slot of the lever arm.

Abstract: The present disclosure relates to a method of manufacturing a model car body, including preparing a steel mold comprising a core plate with an inner core, a top plate and at least two side plates; attaching at least one pre-fabricated plastic block to a side of the inner core of the core plate; combining the core plate, the top plate and the at least two side plates with each other, wherein a cavity is formed among the top plate, the side plates, the inner core of the core plate and the at least one pre-fabricated plastic block; injecting melted plastic material into the cavity, wherein the melted plastic material is filled with the cavity and the at least one pre-fabricated plastic block is encased by the melted plastic material; solidifying the melted plastic so as to form the model car body, wherein the at least one pre-fabricated plastic block is integrated with the plastic model car body; separating the core plate, the top plate and the at least two side plates from each other; and releasing the model ca

Abstract: The invention provides an endoscope having a lens holder, wherein the lens holder includes a body containing a sintered feedstock and machined surfaces. The invention also provides a method of manufacturing the endoscope which includes the steps of molding a metal blank by a MIM process, wherein the metal blank is “near net shape” and has a sprue, a post, and optionally an outer shell, machining the inner surfaces and then the outer surfaces of the metal blank to form a lens holder, installing a lens in the lens holder, and assembling the lens holder having the lens into the endoscope.

Abstract: The invention provides an endoscopic video camera having a polymeric knob assembly, wherein the polymeric material used for manufacturing the knob assembly includes polyphenylsulfone resin, titanium dioxide, tin oxide, and colored metallic additives, is capable of withstanding sterilization, and has a metallic cosmetic appearance. The invention also provides methods of manufacturing the knob assembly by plastic injection molding processes, wherein undesirable molding characteristics are concentrated on portions of the knob assembly that are removed by secondary machining or post machining.

Abstract: Provided are larders systems, aircraft equipped with such systems, and methods of operating such systems. A larder system includes at least two larder cases removably disposed in the same compartment of a larder enclosure. The two cases are detachably interlocked with each other such that removal of the outer case from the enclosure advances the inner case closer to the opening. After the removal of the outer case, the inner case may be retained at the opening. The two cases may be interlocked when pushed against each other, such as when the outer case is inserted into the compartment containing the inner case. In some embodiments, a larder case may be interlocked with the larder enclosure or one of its components, such as a door. This enclosure interlocking allows for the larder case to retain its interlocked position when, for example, the enclosure is only partially filed.

Abstract: The invention provides an endoscopic video camera having a polymeric knob assembly, wherein the polymeric material used for manufacturing the knob assembly includes polyphenylsulfone resin, titanium dioxide, tin oxide, and colored metallic additives, is capable of withstanding sterilization, and has a metallic cosmetic appearance. The invention also provides methods of manufacturing the knob assembly by plastic injection molding processes, wherein undesirable molding characteristics are concentrated on portions of the knob assembly that are removed by secondary machining or post machining.

Abstract: The invention provides an endoscopic video camera having a polymeric knob assembly, wherein the polymeric material used for manufacturing the knob assembly includes polyphenylsulfone resin, titanium dioxide, tin oxide, and colored metallic additives, is capable of withstanding sterilization, and has a metallic cosmetic appearance. The invention also provides methods of manufacturing the knob assembly by plastic injection molding processes, wherein undesirable molding characteristics are concentrated on portions of the knob assembly that are removed by secondary machining or post machining.

Abstract: The present subject matter is directed to water disinfection by pulsed electric field (PEF) systems. The present subject matter relates to a pulsed electric field assembly with a separator that separates and disinfects the microorganisms in drinking water. The present subject matter relates to an anti-corrosion electrode, particularly an electrode having a zeolite coating layer serving as a protector, a process for the preparation a zeolite coating on a conducting electrode substrate, and application of the zeolite coated electrode on water electrolysis and PEF systems.

Abstract: The invention provides an endoscopic video camera having a polymeric knob assembly, wherein the polymeric material used for manufacturing the knob assembly includes polyphenylsulfone resin, titanium dioxide, tin oxide, and colored metallic additives, is capable of withstanding sterilization, and has a metallic cosmetic appearance. The invention also provides methods of manufacturing the knob assembly by plastic injection molding processes, wherein undesirable molding characteristics are concentrated on portions of the knob assembly that are removed by secondary machining or post machining.