Abstract: In an internal combustion engine a fuel-air mixture having compression temperatures and pressures sufficiently low as not to support auto ignition, ignition is achieved by injecting igniting active radicals into the air-fuel mixture. In one embodiment the active radicals are provided by withdrawing a portion of the mixture, treating it to produce active radicals in the portion and returning the portion to the mixture. Treatment of the portion typically includes simultaneously injecting, mixing, and compression of a predetermined amount of pilot fuel within the portion.