Abstract: The present invention discloses a method of producing a medical implant adopting additive manufacturing including: distributing magnesium-zinc-zirconium alloy powder on a substrate to form a powder layer; generating a high-energy beam within a specific power range and directing the high-energy beam to the powder layer through a probe to sinter a region of the powder layer; distributing the plurality of magnesium-zinc-zirconium alloy powder on the sintered region of the powder layer; and repeating above steps until the medical implant is formed.

Abstract: This invention is related to an anchor implantation system capable of being fixed on a bone and including an anchor and an awl. The anchor comprises an inner side, an outer side and a perforation in connection therewith, and the anchor further includes an accommodating portion and a thread portion. The accommodating portion and the thread portion are disposed at the inner side and the outer side of the anchor, respectively. One end of the awl penetrates the accommodating portion and protrudes from the perforation, and the shape of the cross section of the awl is non-circular. The awl is rotatable to drive the anchor, so that the anchor is screwed into the bone with the thread portion. The present disclosure provides a rotating awl with a non-circular shape in cross section to enlarge a pilot hole when drilling the bone, so that the anchor can be screwed into the bone while drilling.

Abstract: A biodegradable metal alloy for anchoring detached tissue to hard tissue, a method for making the same and a process for using the same are revealed. The biodegradable metal alloy includes a magnesium-zinc-zirconium (Mg—Zn—Zr) alloy and a magnesium fluoride (MgF2) coating over the Mg—Zn—Zr alloy. The Mg—Zn—Zr alloy is a magnesium alloy containing 2.5-6.0 wt % zinc (Zn) and 0.42-0.80 wt % zirconium (Zr). Thereby the present biodegradable metal alloy not only provides sufficient fixation strength for anchoring detached tissue to hard tissue effectively but also promotes the bone growth and avoids metal/alloy artifacts in images.

Abstract: A biodegradable metal alloy for anchoring detached tissue to hard tissue, a method for making the same and a process for using the same are revealed. The biodegradable metal alloy includes a magnesium-zinc-zirconium (Mg—Zn—Zr) alloy and a magnesium fluoride (MgF2) coating over the Mg—Zn—Zr alloy. The Mg—Zn—Zr alloy is a magnesium alloy containing 2.5-6.0 wt % zinc (Zn) and 0.42-0.80 wt % zirconium (Zr). Thereby the present biodegradable metal alloy not only provides sufficient fixation strength for anchoring detached tissue to hard tissue effectively but also promotes the bone growth and avoids metal/alloy artifacts in images.

Abstract: A composition for repairing cartilage tissues includes a scaffold and a plurality of endothelial progenitor cells. The endothelial progenitor cells adhere on the scaffold. A method of making the composition for repairing cartilage tissue is also disclosed. This is advantageous for safely and quickly repairing cartilage tissues by using the composition and the manufacturing method thereof.

Abstract: A method for repairing cartilage tissues includes the following steps: adhering a plurality of endothelial progenitor cells onto a scaffold to form a composition, and implanting the composition into an individual. The present invention also provides a method of cartilage defect treatment and a method for proliferating the cartilage tissues. The methods in accordance with the present invention are advantageous for safely and quickly repairing or proliferating cartilage tissues for disease treatment and physical function maintenance.

Abstract: A method for improving myocardial infarction by intramyocardial or transendocardial injection of peptide nanofibers is disclosed. The method firstly provides a pharmaceutical composition having a biologically compatible peptide hydrogel formed by a plurality of self-assembling peptide nanofibers and selectively having at least one type of autologous stem cells mixed with the self-assembling peptide nanofibers, and then the pharmaceutical composition is administered to an entire infarcted area of myocardium tissue with myocardial infarction by intramyocardial or transendocardial injection. Thus, adverse cardiac remodeling and dysfunction after acute infraction can be attenuated, while the therapeutic myocardial angiogenesis, the myocardial capillary density and potential myogenesis can be enhanced.