Patents by Inventor Ming Loo

Ming Loo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240182548
    Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to the spike protein of SARS-CoV-2 and methods of making and selecting the same. The antibodies can be used, for example, in prophylaxis, post-exposure prophylaxis, or treatment of SARS-CoV-2 infection. The antibodies can also be used to detect SARS-CoV-2 infection in subject.
    Type: Application
    Filed: November 30, 2023
    Publication date: June 6, 2024
    Inventors: Mark ESSER, James STEINHARDT, Patrick MCTAMNEY, II, Yueh-Ming LOO, Reena M. VARKEY, Qun DU, Saravanan RAJAN
  • Publication number: 20240092875
    Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to the spike protein of SARS-CoV-2 and methods of using such antibodies and antigen-binding fragments thereof for the prevention and treatment of Coronavirus Disease 2019 (COVID-19) in a subject.
    Type: Application
    Filed: August 9, 2023
    Publication date: March 21, 2024
    Inventors: Robert GASSER, Mark ESSER, Patrick MCTAMNEY, II, Yueh-Ming LOO, Reena M. VARKEY, Qun DU, James STEINHARDT, Saravanan RAJAN
  • Publication number: 20230279078
    Abstract: The present disclosure provides SARS-CoV-2 spike proteins and trimers containing such spike proteins. The present disclosure also provides antibodies and antigen-binding fragments thereof that specifically bind to the spike protein of SARS-CoV-2. The proteins, trimers, and antibodies can be used, for example, to detect anti-SARS-CoV-2 antibodies in sample obtained from a subject.
    Type: Application
    Filed: July 19, 2021
    Publication date: September 7, 2023
    Inventors: GLEN HUGHES, RUTH E. MARCH, MARK ESSER, PATRICK MCTAMNEY II, YUEH-MING LOO, REENA M. VARKEY, QUN DU, JAMES STEINHARDT, SARAVANAN RAJAN
  • Publication number: 20220331418
    Abstract: Compositions and methods are provided that enable activation of innate immune responses through RIG-I like receptor signaling. The compositions and methods incorporate synthetic nucleic acid pathogen associated molecular patterns (PAMPs) that comprise elements initially characterized in, and derived from, the hepatitis C virus genome.
    Type: Application
    Filed: April 4, 2022
    Publication date: October 20, 2022
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Michael J. Gale, JR., Gretja Schnell, Yueh-Ming Loo
  • Patent number: 11324817
    Abstract: Compositions and methods are provided that enable activation of innate immune responses through RIG-I like receptor signaling. The compositions and methods incorporate synthetic nucleic acid pathogen associated molecular patterns (PAMPs) that comprise elements initially characterized in, and derived from, the hepatitis C virus genome.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: May 10, 2022
    Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Michael J. Gale, Jr., Gretja Schnell, Yueh-Ming Loo
  • Publication number: 20220041694
    Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to the spike protein of SARS-CoV-2 and methods of using such antibodies and antigen-binding fragments thereof for the prevention and treatment of Coronavirus Disease 2019 (COVID-19) in a subject.
    Type: Application
    Filed: August 9, 2021
    Publication date: February 10, 2022
    Inventors: Robert GASSER, Mark ESSER, Patrick MCTAMNEY, II, Yueh-Ming LOO, Reena M. VARKEY, Qun DU, James STEINHARDT, Saravanan RAJAN
  • Publication number: 20210355196
    Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to the spike protein of SARS-CoV-2 and methods of making and selecting the same. The antibodies can be used, for example, in prophylaxis, post-exposure prophylaxis, or treatment of SARS-CoV-2 infection. The antibodies can also be used to detect SARS-CoV-2 infection in subject.
    Type: Application
    Filed: May 17, 2021
    Publication date: November 18, 2021
    Applicant: AstraZeneca UK Limited
    Inventors: Mark ESSER, James STEINHARDT, Patrick MCTAMNEY, II, Yueh-Ming LOO, Reena M. VARKEY, Qun DU, Saravanan RAJAN
  • Patent number: 11137473
    Abstract: An acoustic goniometer device may include at least four microphones coupled to a collapsible structure. The device may further include a processor configured to receive at least four sound signals from the at least four microphones and to determine a direction of arrival of a sound event within three dimensions based on a time shift between the at least four sound signals. A method may include receiving at least four sound signals from at least four microphones coupled to a collapsible structure and determining a direction of arrival of a sound event within three dimensions based on a time shift between the at least four sound signals.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: October 5, 2021
    Assignee: Boise State University
    Inventors: Sin Ming Loo, Mark Laverty
  • Publication number: 20210286037
    Abstract: An acoustic goniometer device may include at least four microphones coupled to a collapsible structure. The device may further include a processor configured to receive at least four sound signals from the at least four microphones and to determine a direction of arrival of a sound event within three dimensions based on a time shift between the at least four sound signals. A method may include receiving at least four sound signals from at least four microphones coupled to a collapsible structure and determining a direction of arrival of a sound event within three dimensions based on a time shift between the at least four sound signals.
    Type: Application
    Filed: March 16, 2020
    Publication date: September 16, 2021
    Inventors: Sin Ming Loo, Mark Laverty
  • Publication number: 20200276294
    Abstract: Compositions and methods are provided that enable activation of innate immune responses through RIG-I like receptor signaling. The compositions and methods incorporate synthetic nucleic acid pathogen associated molecular patterns (PAMPs) that comprise elements initially characterized in, and derived from, the hepatitis C virus genome.
    Type: Application
    Filed: October 7, 2019
    Publication date: September 3, 2020
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Michael J. Gale, JR., Gretja Schnell, Yueh-Ming Loo
  • Patent number: 10434164
    Abstract: Compositions and methods are provided that enable activation of innate immune responses through RIG-I like receptor signaling. The compositions and methods incorporate synthetic nucleic acid pathogen associated molecular patterns (PAMPs) that comprise elements initially characterized in, and derived from, the hepatitis C virus genome.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: October 8, 2019
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Michael J. Gale, Jr., Gretja Schnell, Yueh-Ming Loo
  • Publication number: 20180104325
    Abstract: Compositions and methods are provided that enable activation of innate immune responses through RIG-I like receptor signaling. The compositions and methods incorporate synthetic nucleic acid pathogen associated molecular patterns (PAMPs) that comprise elements initially characterized in, and derived from, the hepatitis C virus genome.
    Type: Application
    Filed: September 21, 2017
    Publication date: April 19, 2018
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Michael J. Gale, JR., Gretja Schnell, Yueh-Ming Loo
  • Patent number: 9775894
    Abstract: Compositions and methods are provided that enable activation of innate immune responses through RIG-I like receptor signaling. The compositions and methods incorporate synthetic nucleic acid pathogen associated molecular patterns (PAMPs) that comprise elements initially characterized in, and derived from, the hepatitis C virus genome.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: October 3, 2017
    Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Michael J. Gale, Jr., Gretja Schnell, Yueh-Ming Loo
  • Patent number: 9604589
    Abstract: The present invention in one or more embodiments provides a polymeric bracket for instrument panel side passenger knee protection, the polymeric bracket including first and second legs spaced apart from each other and to support an instrument panel at an assembly position, and a waist connecting the first and second legs and to support a cross car beam at the assembly position.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: March 28, 2017
    Assignee: Ford Global Technologies, LLC
    Inventors: Tien Vo, Ming Loo
  • Publication number: 20150017207
    Abstract: Compositions and methods are provided that enable activation of innate immune responses through RIG-I like receptor signaling. The compositions and methods incorporate synthetic nucleic acid pathogen associated molecular patterns (PAMPs) that comprise elements initially characterized in, and derived from, the hepatitis C virus genome.
    Type: Application
    Filed: July 9, 2014
    Publication date: January 15, 2015
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Michael J. Gale, JR., Gretja Schnell, Yueh-Ming Loo
  • Patent number: 8397371
    Abstract: In one embodiment and method of the present invention, a coil of a write head is created by forming a P1 pedestal layer and a back gap layer and further forming a coil pattern consistent with the coil to be formed and insulator spacers dispersed in the coil pattern, using a non-damascene process, thereafter the coil is formed by plating using a damascene process.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: March 19, 2013
    Assignee: HGST Netherlands B.V.
    Inventors: Daniel Wayne Bedell, David Patrick Druist, Edward Hin Pong Lee, Jennifer Ai-Ming Loo, Vladimir Nikitin, Sue Siyang Zhang
  • Publication number: 20100163523
    Abstract: In one embodiment and method of the present invention, a coil of a write head is created by forming a P1 pedestal layer and a back gap layer and further forming a coil pattern consistent with the coil to be formed and insulator spacers dispersed in the coil pattern, using a non-damascene process, thereafter the coil is formed by plating using a damascene process.
    Type: Application
    Filed: February 17, 2010
    Publication date: July 1, 2010
    Inventors: Daniel Wayne Bedell, David Patrick Druist, Edward Hin Pong Lee, Jennifer Ai-Ming Loo, Vladimir Nikitin, Sue Siyang Zhang
  • Patent number: 7729084
    Abstract: In one embodiment and method of the present invention, a coil of a write head is created by forming a P1 pedestal layer and a back gap layer and further forming a coil pattern consistent with the coil to be formed and insulator spacers dispersed in the coil pattern, using a non-damascene process, thereafter the coil is formed by plating using a damascene process.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: June 1, 2010
    Assignee: Hitachi Global Storage Technologies Netherlands B.V.
    Inventors: Daniel Wayne Bedell, David Patrick Druist, Edward Hin Pong Lee, Jennifer Ai-Ming Loo, Vladimir Nikitin
  • Patent number: 7633711
    Abstract: A magnetic write head for perpendicular magnetic recording that has a helical coil design that reduces manufacturing complexity and increases cycle time for manufacture. The write head includes a write pole and a helical write coil having upper coil portions that pass above the write pole and lower coil portions that pass below the write pole. The upper and lower coil portions are connected with another by connection studs. Whereas the upper and lower coil portions are constructed of a non-magnetic, electrically conductive material such as Cu, the connection studs are constructed of a magnetic, electrically conductive material such as NiFe. By constructing the connection studs of a magnetic material, they can be constructed in the same manufacturing steps used to manufacture various magnetic structures of the write head, such as a magnetic shaping layer and/or the back gap.
    Type: Grant
    Filed: February 7, 2007
    Date of Patent: December 15, 2009
    Assignee: Hitachi Global Storage Technologies Netherlands B.V.
    Inventors: Wen-Chien David Hsiao, Edward Hin Pong Lee, Jennifer Ai-Ming Loo
  • Publication number: 20090057160
    Abstract: A method for manufacturing a write head with a helical coil having a very small and well controlled spacing between adjacent coil leads. The method includes forming a first set of coil leads, then conformally depositing a thin layer of electrically insulating material such as alumina over the first set of coil leads and over the substrate. An electrically conductive seed layer is then deposited over the thin layer of non-magnetic, electrically insulating material An electrically conductive material such as Cu is then deposited by electroplating in order to form a second set of electrically conductive leads interspersed within the first set of electrically conductive leads, each of the second set of leads being separated from the second set of leads by a portion of the thin layer of non-magnetic, electrically insulating material.
    Type: Application
    Filed: August 27, 2007
    Publication date: March 5, 2009
    Inventors: Donald G. Allen, Ming Jiang, Jennifer Ai-Ming Loo, Aron Neuhaus, Vladimir Nikitin, Yuan Yao