Abstract: The present disclosure provides humanized antibodies specific to human interleukin 20 (IL-20) and uses thereof in treating diseases associated with the IL-20 signaling pathway, e.g., osteoporosis, inflammatory disease (e.g., rheumatoid arthritis), cancer, stroke, and renal failure.

Abstract: An electrical connector includes an insulation body and a contact. The insulation body includes a first side and a second side positioned opposite to the first side. The contact is received in the insulation body and includes a first elastic gripping portion adjacent to the first side of the insulation body and a second elastic gripping portion adjacent to the second side of the insulation body.

Abstract: The disclosure relates to a meter for monitoring usage of power provided by a power transmission system to a site. The meter comprises: a communication module to generate communications carried over the transmission system; a relay having a first position connecting power from the transmission system to the site and a second position disconnecting power; a request manager module to process messages from a head end associated with the transmission system; a meter module connected to a power feed associated with the transmission system to provide readings relating to the power used at the site; an event manager module to evaluate new events queued in a message queue received by the meter and after evaluating the new events to send a message to the head end relating to the earliest event in the message queue; a connection manager module managing the power connection to the transmission system.

Abstract: A clock tree circuit includes a clock source and a tree circuit. The clock source generates a signal. The tree circuit at least includes five driving units and a metal connection element. A first driving unit has an input terminal for receiving the signal, and an output terminal coupled to a first node. A second driving unit has an input terminal coupled to the first node, and an output terminal coupled to a second node. A third driving unit has an input terminal coupled to the first node, and an output terminal coupled to a third node. A fourth driving unit has an input terminal coupled to the second node. A fifth driving unit has an input terminal coupled to the third node. The metal connection element is coupled between the second node and the third node, and configured as a short-circuited element.

Abstract: The present invention provides a pacemaker signal detecting method, a pacemaker signal detecting system, and an electrocardial detecting device. The pacemaker signal detecting system pre-processes an original pacemaker signal separated from a pacemaker electrocardial signal, calculates a number of basic morphological features based on the pre-processed original pacemaker signal, confirms an authenticity of a pacemaker signal according to the calculated basic morphological features, and records positions of the true pacemaker signal has been confirmed. The basic morphological features include a width, a slew rate, and amplitude of the pacemaker signal. The electrocardial detecting device of the present invention can detect the pacemaker signal more precisely and output the electrocardial signal marked with the pacemaker signal.

Abstract: A dynamic element matching method for a multi-unit-element digital-to-analog converter having unit elements comprises several steps. An element selection probability is determined as a function of a number of the unit elements and a digital signal. Next, loop filter output signals are generated as a function of the determined element selection probability and control signals for the unit elements. Certain ones of the unit elements are selected as a function of the generated loop filter output signals. The selected certain ones of the unit elements are activated for output of the converter.

Abstract: Reducing inflammatory pain in a subject having or being suspected of having an inflammatory pain using an IL-20 antagonist, which can be an antibody that blocks a signaling pathway mediated by IL-20. Such antibodies include anti-IL-20 antibodies and anti-IL-20R antibodies that specifically block the IL-20 signaling pathway.

Abstract: A connection terminal for releaseably connecting a cable is disclosed having a terminal body, a contact arm, a cable fastening member, and a cable releasing member. The terminal body has a mating end and an opposite terminating end. The contact arm extends continuously from the mating end of the terminal body. The cable fastening member is positioned on the terminating end of the terminal body. The cable releasing member is positioned on the cable fastening member.

Abstract: An electrical connector for releaseably connecting a cable is disclosed having a housing and a plurality of connection terminals. The housing has a plurality of receiving passages extending through the housing in a cable insertion direction. The plurality of connection terminals are each detachably positioned in the receiving passages. Each connection terminal has a terminal body having a mating end and an opposite terminating end onto which the cable is electrically connected. Each connection terminal also has a contact arm extending continuously from the mating end of the terminal body; a cable fastening member positioned on the terminating end of the terminal body; and a cable releasing member positioned on the cable fastening member.

Abstract: Treating a disorder (e.g., osteoporosis, renal failure, or diabetic nephropathy) associated with a signaling pathway mediated by IL-20 receptor with an agent that suppresses IL-20 receptor activity, e.g., an antibody that neutralizes IL-20 receptor via binding to IL-20R1, an antisense nucleic acid that suppresses expression of IL-20R1, a small molecule that inhibits IL-20 receptor activity, or a dominant negative mutant of IL-19, IL-20, or IL-24.

Abstract: The present invention provides a nutritional composition for improving a patient with heart failure; the nutritional composition is consisting of therapeutically effective high amounts of leucine and histidine. The present invention also provides the nutritional supplement comprising the nutritional composition, which may be a beverage product, a dietary supplement or food. The present invention further provides a method of using the nutritional supplement for treating patients with heart failure.

Abstract: The disclosure relates to a meter for monitoring usage of power provided by a power transmission system to a site. The meter comprises: a communication module to generate communications carried over the system; a request manager module to process messages received from a head end of the system; a meter module connected to a power feed of the system; a connection manager module to evaluate readings and data and to generate connection signals for the meter in view of the readings; and a relay having a first position where the power is connected to the site and a second position where the power is disconnected, the relay being controlled by the connection signals. The connection manager module generates a first signal for the relay to disconnect the power when an over-voltage condition or an over-current condition on the system has been detected.

Abstract: The disclosure relates to a meter for monitoring usage of power provided by a power transmission system to a site and a related method. The meter comprises: a meter module connected to a power feed associated with the transmission system to provide readings relating to the power; a connection to a household AC power supply providing power to the meter; a rectifier circuit connected to the AC power to generate a DC power signal; a voltage detection circuit to detect a low voltage condition where an output from the rectifier circuit drops below an operational threshold for the meter and to generate a low voltage signal upon detection of same; and a message generation module for receiving the low voltage signal and for generating a power loss message for transmission carried on a message carrier having on a carrier having frequency between approximately 2 MHz and 30 MHz.

Abstract: The disclosure relates to a server, system and method for communicating with a meter at a remote premise through power transmission lines. The system comprises a head end with a server for collecting and analyzing data from meters; a power transmission network connected to the meters and to the head end; and a gateway. The network provides both power to the remote location and data communications; the network includes a first network providing a first voltage and a second network connected to the first network. The server comprises a processor and a memory module storing instructions for execution on the processor. The gateway is a bridge between the first and second networks. Network communications may follow Internet Protocol (IP) communication standards. Based on the load index, each meter can generate and send its response to the server and the server will be able to process its response.

Abstract: An angle detecting module for a motor rotor is provided. The angle detecting module includes a permanent-magnet synchronous motor, three linear hall components and a processing device. The permanent-magnet synchronous motor includes a stator and a rotor. The three linear hall components are disposed on the stator; and the linear hall components are spaced by electrical 120 degrees. Each of the linear hall components outputs an analog signal after measuring a magnetic field position of the rotor, and each of the analog signals has magnetically saturated third harmonic component. The processing device is electrically connected to the linear hall components, and the processing device optimizes each of the analog signals and generates an average rotor angle.

Abstract: Humanized antibodies specific to human interleukin 20 (IL-20) and uses thereof in treating diseases associated with the IL-20 signaling pathway, e.g., osteoporosis, inflammatory disease (e.g., rheumatoid arthritis), cancer, stroke, and renal failure.

Abstract: The disclosure relates to a meter for monitoring usage of power provided by a power transmission system to a site. The meter comprises: a meter module connected to a power feed associated with the power transmission system to provide readings relating to the power; a messaging module to provide messages to the power transmission system; a connection to an alternating current (AC) power supply; a rectifier circuit connected to the AC power supply to generate a direct current (DC) power signal; a capacitive circuit connected to an output of the rectifier circuit, the capacitive circuit including a capacitor for storing a voltage for temporarily providing replacement power for the rectifier circuit; and a switching regulator circuit connected to the output of the rectifier circuit and the capacitive circuit, the switching regulator converting the DC voltage signal to a stepped down voltage signal for the meter module.

Abstract: The disclosure relates to a system and method for communicating with a meter at a remote premise through power transmission lines. The system comprises a head end for collecting and analyzing data from the meter; a power transmission network connected to the meter and to the head end; and a gateway. The network provides both power to the remote location and data communications; the network includes a first network providing a first voltage and a second network connected to the first network and the remote location. The gateway is a bridge between the first and second networks; the gateway provides an interface communication point. The communications are carried over the network following Internet protocol (IP) communication standards.

Abstract: A method for diagnosing heart failure in a subject is provided. The method includes steps of measuring a biological sample of the subject to obtain an amount of at least one biomarker selected from the group consisting of xanthine, spermidine, propionylcarnitine, butyrylcarnitine and P-cresyl sulfate; and comparing the amount of the at least one biomarker to a reference. Moreover, the present invention relates to a method for staging heart failure or evaluating a prognosis of heart failure in a subject.

Abstract: A memory module, comprising: a first pin, arranged to receive a first signal; a second pin, arranged to receive second signal; a first conducting path, having a first end coupled to the first pin; at least one memory chip, coupled to the first conducting path for receiving the first signal; a predetermined resistor, having a first terminal coupled to a second end of the first conducting path; and a second conducting path, having a first end coupled to second pin for conducting the second to a second terminal of the predetermined resistor; wherein the first signal and the second are synchronous and configured to be a differential signal, for enabling a selected memory chip from the at least one memory chip to be accessed.