Patents by Inventor MING-SHU HSIEH

MING-SHU HSIEH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPIDATED FLIPR AND USES THEREOF IN VACCINE
    Publication number: 20240033350
    Abstract: The present disclosure relates to a vaccine composition, comprising a recombinant lipidated FLIPr (rLF), and the use thereof in enhancing humoral and cellular immune responses. The recombinant lipidated FLIPr of present invention may be used as a vaccine candidate that can induce anti-FLIPr responses to overcome FLIPr-mediated inhibition. And unexpectedly, the recombinant lipidated FLIPr may be used as an adjuvant that can enhance other vaccine immune responses, especially in subunit vaccines and inactivated virus vaccines.
    Type: Application
    Filed: August 1, 2023
    Publication date: February 1, 2024
    Inventors: Hsin-Wei CHEN, Ming-Shu HSIEH, Shih-Jen LIU, Ching-Len LIAO
  • MULTIPLE MOSQUITO-BORNE FLAVIVIRUS VACCINE AND USE THEREOF IN INDUCING NEUTRALIZING ANTIBODIES
    Publication number: 20210060152
    Abstract: The present invention relates to a peptide immunogen, comprising at least one copy of amino acid sequence RCPTTGE (called JBP). The peptide immunogen of present invention can induce an effective immune response to two or more mosquito-borne flavivirus. The present invention also provides mono/multivalent virus vaccines to protect animal against multiple mosquito-borne flavivirus infection, including diseases caused by Japanese encephalitis virus (JEV), West Nile virus (WNV), Dengue Virus (DENV), and Zika virus (ZIKV) infections.
    Type: Application
    Filed: September 3, 2020
    Publication date: March 4, 2021
    Inventors: CHING-LEN LIAO, MING-SHU HSIEH, SHU-PEI LIEN