Abstract: The present disclosure provides antibodies and antigen-binding fragments thereof that bind to human CCR8, a pharmaceutical composition comprising said antibody, and use of the antibody or the composition for treating a disease, such as cancer.

Abstract: Systems and methods for electronic displays to use reference voltages to control driving current of illuminators are provided. The reference voltages are used to reduce or eliminate cross talk in driving voltages among different illuminators and driving voltage variations from frame to frame. The transient performance of the driving current of the illuminator (e.g., the current rise/decline time, current overshoot issue, current settling time) may be improved by implementing the reference voltages.

Abstract: This disclosure is directed to a pharmaceutical composition for treating or preventing a disease. The pharmaceutical composition can comprise a polymer-drug nanoaggregate having a polymer and at least one bioactive agent that can comprise STING polypeptide, a nucleic acid encoding said STING polypeptide, a STING inhibitor, a STING activator, a STING agonist, a STING antagonist, a STING modulating molecule, or a combination thereof. The pharmaceutical composition can be a vaccine or an adjuvant for a vaccine. This disclosure is also directed to a method for treating or preventing a disease using the pharmaceutical composition. The disease can include infectious diseases caused by viruses or other pathogens, for example, influenza, rabies, or respiratory illnesses such as severe acute respiratory syndrome (SARS) caused by coronaviruses, such as MERS-CoV, SARS-CoV, and Coronavirus Disease 2019 (COVID-19) caused by the virus SARS-CoV-2 and its variants.

Abstract: A method and a system for controlling cooling of a vehicle, and a vehicle are provided in the present disclosure. In the present disclosure, a maximum value among cooling demand values of cooling objects is used to control a servo component in a cooling system to operate according to an execution opening determined by a preset corresponding relation, so that operating states of the servo components may be correlated and may be comprehensively controlled, so as to prevent the control system from oscillating and improve control stability, thus solving a problem that periodic oscillation of the operating states of the servo components is easily caused and service life of the servo components is affected in existing control modes of the cooling system of the vehicle.

Abstract: Methods, systems, and devices for techniques for firmware enhancement in memory devices are described. A memory system may include a volatile memory device and a non-volatile memory device, which may store a node address mapping. A host system in communication with the memory system may transmit a command instructing the memory system to transfer at least a portion of the node address mapping from the non-volatile memory device to the volatile memory device. The memory system may transmit a response to the command to the host system indicating a status associated with transferring the portion of the node address mapping.

Abstract: A semiconductor device structure is provided. The semiconductor device structure includes a substrate and a first dielectric layer over the substrate. The semiconductor device structure also includes a first metal gate stack and a second metal gate stack over the substrate and the first dielectric layer. The semiconductor device structure further includes a second dielectric layer beside the first metal gate stack and an insulating structure over the substrate. A portion of the insulating structure is between the first metal gate stack and the second metal gate stack. The insulating structure penetrates into the second dielectric layer.

Abstract: There is provided a smoke detector including a substrate, a light source and a light sensor. The light source and the light sensor are arranged adjacently on the substrate. The substrate is arranged with an asymmetric structure to cause an illumination region of the light source to deviate toward the light sensor thereby increasing a ratio of light intensity reflected by smoke with respect to reference light intensity.

Abstract: A sprayer includes: a container; a passage including a transparent window, a first opening, a second opening and a resonator, wherein when liquid in the container is passed through the resonator via the first opening, the liquid is emitted as a gas via the second opening; and a removable detection unit disposed outside of the passage. The removable detection unit includes: a light source for illuminating the gas in the passage; an optical sensor disposed to detect a parameter of light reflected by the gas; and a processor coupled to the optical sensor for stopping the resonator from generating the gas when the parameter is below a threshold. The passage further includes a cavity disposed on a bottom surface of the passage in front of the optical sensor, wherein when the gas in the passage contacts the bottom surface, resultant water vapour will enter the cavity.

Abstract: The present disclosure provides a display panel and a display device. The display panel includes a substrate, a light-emitting layer located at a side of the substrate, and an encapsulation layer located at s side of the light-emitting layer facing away from the substrate; the light-emitting layer comprises a plurality of light-emitting elements, and the encapsulation layer comprises a cut-off filter film layer, wherein the plurality of the light-emitting elements generate emitted light of at least two colors; wherein, the cut-off filter film layer comprises a plurality of filter areas, and one filter area filters the emitted light of one color, so that a wavelength range of the emitted light transmitting through the filter area is narrower than that of emergent light.

Abstract: Embodiments analyze a query pattern of an incoming query on a database, perform a semantic analysis of the query pattern of the incoming query, generate a re-write query that has an improved query performance in comparison to a query performance of the incoming query based on the analyzed query pattern and the semantic analysis; build a query model using machine learning based on at least one of the query pattern and the semantic analysis; and apply the re-write query by performing the re-write query on the database to provide the improved query performance.

Abstract: Compositions and methods are provided herein for treating intestinal glycocalyx dysfunction. The composition can comprise a chito-oligosaccharide (COS), and optionally a human milk oligosaccharide (hMO) in an amount sufficient to maintain an intestinal glycocalyx and a pharmaceutically acceptable carrier. The composition can be formulated as an oral dosage form or a parenteral dosage form. The method can comprise identifying intestinal glycocalyx dysfunction in the subject. The method can further comprise administering to the subject a COS in an amount and at a frequency sufficient to prevent, stabilize and reverse damage in the intestinal glycocalyx.

Abstract: A display panel and a display apparatus. The display panel includes a substrate, and pixel islands (Pi) arranged in an array on the substrate, and at least one pixel island (Pi) includes a plurality of pixel drive circuits (10) and a plurality of light emitting devices, wherein a light emitting device includes a first electrode (20), and at least one pixel drive circuit (10) is electrically connected with at least one light emitting device; first electrodes (20) of a plurality of light emitting devices on a same pixel island are arranged in a first direction, and an orthographic projection of a first electrode (20) of at least one light emitting device on the substrate is at least partially overlapped with an orthographic projection of at least two pixel drive circuits (10) on the substrate.

Abstract: Provided are a display baseplate, a mould assembly, a spliced display module, and a display apparatus. The display baseplate includes a backplate light emitters and an encapsulation layer. The backplate includes a first main surface and a second main surface that are opposite to each other, and side surfaces connected to the first main surface and the second main surface light emitters are located on the first main surface, the encapsulation layer is at least partially located on the first main surface and covers the plurality of light emitters. The spliced display module includes a splicing units, the splicing units each include a splicing frame and a display baseplate, the display baseplate is fixed on the splicing frame with the light emitters away from the splicing frame; and the splicing frames of adjacent splicing units are spliced together. The display apparatus includes a display baseplate or a spliced display module.

Abstract: The present disclosure relates, according to some embodiments, to methods for preparing a library for sequencing. For example, a method may comprise (a) in a coupled reaction, (i) contacting a population of nucleic acid fragments with a tailing enzyme to produce tailed fragments, and (ii) ligating to the tailed fragments a sequencing adapter with a ligase to produce adapter-tagged fragments; and/or separating adapter-tagged fragments from the tailing enzyme and the ligase to produce separated adapter-tagged fragments and, optionally, separated tailing enzyme and/or separated ligase. In some embodiments, a tailing enzyme and/or a ligase used in library preparation may be immobilized enzymes.

Abstract: There is provided an optical machine of a smoke detector including a substrate, a light source, a light sensor and a light blocking member. The light source and the light sensor are arranged on the substrate in a first direction. The light blocking member is arranged upon the light source and blocks a part of an emission angle of the light source in the first direction far away from the light sensor.

Abstract: A method for reconstructing a primary voltage of a potential transformer (PT) based on an inverse black box model and an inverse electromagnetic duality model includes: collecting a secondary voltage signal of a power system by the PT, and dividing the secondary voltage signal into a low-frequency voltage component and a high-frequency voltage component; performing primary voltage reconstruction by applying the inverse black box model on the high-frequency voltage component, to obtain a primary-voltage high-frequency voltage component; performing primary voltage reconstruction by applying the inverse electromagnetic duality model on the low-frequency voltage component, to obtain a primary-voltage low-frequency voltage component; and integrating the primary-voltage high-frequency voltage component and the primary-voltage low-frequency voltage component, to obtain the primary voltage of the power system.

Abstract: A display device and a control method therefor are disclosed. The display device includes: a first backlight module; a second backlight module located at a light emergent side of the first backlight module; and a display panel located at a side of the second backlight module facing away from the first backlight module; where the first backlight module includes a first light board, and the first light board emits light to a side of the second backlight module; the second backlight module includes at least one second light board, second light boards of the at least one second light board are stacked, and the second light boards transmit the light emitted by the first backlight module and emit light to the display panel; the first light board includes a plurality of first light sources, each second light board of the second light boards includes a plurality of second light sources.

Abstract: The present invention discloses a Acinetobacter baumannii immunogenic protein and its composition and application. This invention provides a protein, comprising 39 amino acids of the N-terminal ?-helix part of the Ata protein transport functional domain of Acinetobacter baumannii and an adjuvant protein; amino acid sequence of said 39 amino acids of the N-terminal ?-helix part of the Ata protein transport functional domain of Acinetobacter baumannii is shown as the 127th-165th amino acid residues of SEQ ID NO:2. In present invention the 39 amino acids of the N-terminal ?-helix part of surface protein Ata (Acinetobacter trimeric autotransporter) of Acinetobacter baumannii, was took to fuse with CTB, and express in BL21. The protein was purified by a nickel column, and used to intraperitoneally immunize mouses by 2.5 ?g/mouse. Its immunogenicity and immunoprotection was verified through the animal experiments, which proves it has a good effect of anti-infection of Acinetobacter baumannii.

Abstract: A 3D loop article made of a material comprising polyethylene, ethylene/?-olefin copolymer, or a blend of polyethylene and ethylene/?-olefin copolymer, wherein the material has a low-perfection crystal melting enthalpy, calculated within a temperature range of 15-80° C., of less than or equal to 30 J/g.

Abstract: A wearable device includes a case and a temperature sensing device. The case has a first opening. The temperature sensing device is disposed inside the case of the wearable device. The temperature sensing device includes a first substrate, a sensor chip, and a metal shielding structure. The sensor chip is disposed on the first substrate. The metal shielding structure surrounds the sensor chip, and has a second opening. The sensor chip faces towards the first opening and the second opening.