Abstract: The disclosure provides a method of active immunotherapy for a cancer patient, comprising administering vaccines against Globo series antigens (i.e., Globo H, SSEA-3 and SSEA-4). Specifically, the method comprises administering Globo H-CRM197 (OBI-833/821) in patients with cancer. The disclosure also provides a method of selecting a cancer patient who is suitable as treatment candidate for immunotherapy. Exemplary immune response can be characterized by reduction of the severity of disease, including but not limited to, prevention of disease, delay in onset of disease, decreased severity of symptoms, decreased morbidity and delayed mortality.

Abstract: A chip packaging structure and a method for fabricating the same are provided. The chip package structure includes a conductive substrate, a dam and a metal shielding layer. The conductive substrate includes a substrate, vias and electrodes. The substrate has first and second board surfaces opposite to each other. The vias penetrate through the first board surface and the second board surface, and a part of the vias is disposed in a first die-bonding region on which a chip is to be arranged. The electrodes extend from the first board surface to the second board surface through the vias. The dam is formed on the first board surface to surround the first die-bonding region, and the dam has a height higher than that of the chip. The metal shielding layer covers the dam and a part of the first board surface that do not overlap with the electrodes.

Abstract: A virtual private network communication system, a routing device and a method thereof are provided. The system includes a server and a plurality of routing devices. The routing devices respectively transmit registration information to the server, wherein the registration information includes a recognition string. The routing devices include a first routing device and a second routing device. The first routing device transmits a positioning request to the server, and the server transmits the positioning request to a part of or all of the routing devices according to the recognition string. When the second routing device receives the positioning request, the second routing device transmits positioning information according to the positioning request to the first routing device via the server. The first routing device directly establishes a connection with the second routing device according to the positioning information and transmits data after the connection is established.

Abstract: A virtual private network communication system, a routing device and a method thereof are provided. The system includes a server and a plurality of routing devices. The routing devices respectively transmit registration information to the server, wherein the registration information includes a recognition string. The routing devices include a first routing device and a second routing device. The first routing device transmits a positioning request to the server, and the server transmits the positioning request to a part of or all of the routing devices according to the recognition string. When the second routing device receives the positioning request, the second routing device transmits positioning information according to the positioning request to the first routing device via the server. The first routing device directly establishes a connection with the second routing device according to the positioning information and transmits data after the connection is established.