Patents by Inventor Mingyuan Gao

Mingyuan Gao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biocompatible magnetic nanocrystal, powder of a biocompatible magnetic nanocrystal bearing a surface reactive group and preparations thereof
    Patent number: 8226844
    Abstract: This invention is concerned with biocompatible magnetic nanocrystals highly soluble and dispersible in a physiological buffer, powder of biocompatible magnetic nanocrystals and nanocrystals bearing surface reactive N-hydroxysuccinimide ester moiety, and preparations thereof. The magnetic nanocrystals in powder form are highly soluble in a physiological buffer. The resultant aqueous colloidal solution presents long term stability in ambient conditions. Moreover, the carboxyl group on the surface of the magnetic nanocrystals can be converted to N-hydroxysuccinimide ester moiety in an organic solvent. The resultant powder of the magnetic nanocrystals carrying surface N-hydroxysuccinimide ester moiety is soluble and dispersible in an aqueous solution. Different types of biomolecules bearing amino group can covalently be attached to the magnetic nanocrystal simply by mixing them in aqueous solutions.
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: July 24, 2012
    Assignee: Institute of Chemistry, Chinese Academy of Sciences
    Inventors: Mingyuan Gao, Fengqin Hu, Shujie Liu, Xianyong Lu
  • Biocompatible magnetic nanocrystal, powder of a biocompatible magnetic nanocrystal bearing a surface reactive group and preparations thereof
    Patent number: 8017031
    Abstract: This invention is concerned with biocompatible magnetic nanocrystals highly soluble and dispersible in a physiological buffer, powder of biocompatible magnetic nanocrystals and nanocrystals bearing surface reactive N-hydroxysuccinimide ester moiety, and preparations thereof. The magnetic nanocrystals in powder form are highly soluble in a physiological buffer. The resultant aqueous colloidal solution presents long term stability in ambient conditions. Moreover, the carboxyl group on the surface of the magnetic nanocrystals can be converted to N-hydroxysuccinimide ester moiety in an organic solvent. The resultant powder of the magnetic nanocrystals carrying surface N-hydroxysuccinimide ester moiety is soluble and dispersible in an aqueous solution. Different types of biomolecules bearing amino group can covalently be attached to the magnetic nanocrystal simply by mixing them in aqueous solutions.
    Type: Grant
    Filed: January 14, 2008
    Date of Patent: September 13, 2011
    Assignee: Institute of Chemistry, Chinese Academy of Sciences
    Inventors: Mingyuan Gao, Fengqin Hu, Shujie Liu, Xianyong Lu
  • BIOCOMPATIBLE MAGNETIC NANOCRYSTAL, POWDER OF A BIOCOMPATIBLE MAGNETIC NANOCRYSTAL BEARING A SURFACE REACTIVE GROUP AND PREPARATIONS THEREOF
    Publication number: 20110207894
    Abstract: This invention is concerned with biocompatible magnetic nanocrystals highly soluble and dispersible in a physiological buffer, powder of biocompatible magnetic nanocrystals and nanocrystals bearing surface reactive N-hydroxysuccinimide ester moiety, and preparations thereof. The magnetic nanocrystals in powder form are highly soluble in a physiological buffer. The resultant aqueous colloidal solution presents long term stability in ambient conditions. Moreover, the carboxyl group on the surface of the magnetic nanocrystals can be converted to N-hydroxysuccinimide ester moiety in an organic solvent. The resultant powder of the magnetic nanocrystals carrying surface N-hydroxysuccinimide ester moiety is soluble and dispersible in an aqueous solution. Different types of biomolecules bearing amino group can covalently be attached to the magnetic nanocrystal simply by mixing them in aqueous solutions.
    Type: Application
    Filed: March 18, 2011
    Publication date: August 25, 2011
    Applicant: Institute of Chemistry Chinese Academy of Sciences
    Inventors: Mingyuan GAO, Fengqin Hu, Shujie Liu, Xianyong Lu
  • Biocompatible magnetic nanocrystal, powder of a biocompatible magnetic nanocrystal bearing a surface reactive group and preparations thereof
    Publication number: 20080203351
    Abstract: This invention is concerned with biocompatible magnetic nanocrystals highly soluble and dispersible in a physiological buffer, powder of biocompatible magnetic nanocrystals and nanocrystals bearing surface reactive N-hydroxysuccinimide ester moiety, and preparations thereof. The magnetic nanocrystals in powder form are highly soluble in a physiological buffer. The resultant aqueous colloidal solution presents long term stability in ambient conditions. Moreover, the carboxyl group on the surface of the magnetic nanocrystals can be converted to N-hydroxysuccinimide ester moiety in an organic solvent. The resultant powder of the magnetic nanocrystals carrying surface N-hydroxysuccinimide ester moiety is soluble and dispersible in an aqueous solution. Different types of biomolecules bearing amino group can covalently be attached to the magnetic nanocrystal simply by mixing them in aqueous solutions.
    Type: Application
    Filed: January 14, 2008
    Publication date: August 28, 2008
    Inventors: Mingyuan Gao, Fengqin Hu, Shujie Liu, Xianyong Lu