Abstract: A method for inducing reprogramming of a cell of a first type which is not a non-hepatocyte (non-hepatocyte cell), into a cell with functional hepatic drug metabolizing and transporting capabilities, is disclosed. The non-hepatocyte is induced to express or overexpress hepatic fate conversion and maturation factors, cultured in somatic cell culture medium, hepatocyte cell culture medium and hepatocyte maturation medium for a sufficient period of time to convert the non-hepatocyte cell into a cell with hepatocyte-like properties. The iHeps induced according to the methods disclosed herein are functional induced hepatocytes (iHeps) in that they express I and II drug-metabolizing enzymes and phase III drug transporters and show superior drug metabolizing activity compared to iHeps obtained by prior art methods. The iHeps thus provide a cell resource for pharmaceutical applications.

Abstract: A device includes a substrate with a die over the substrate. A molding compound surrounds the die and includes a structural interface formed along a peripheral region of the molding compound.

Abstract: Embodiments of the present invention relate to techniques for creating policies. A plurality of objects representative of semantic objects are provided to a user. An arrangement of a subset of the objects, the arrangement representative of a policy, is received. The arrangement is converted to instructions for implementation by an application configured to implement policies. One or more of the objects may include fields and/or controls for specifying criteria of semantic objects represented by the objects.

Abstract: A resistive random access memory is provided to solve the problem of low switching speed of the conventional resistive random access memory. The resistive random access memory may include a thermally conductive layer, a first electrode layer, a heat preserving element, a resistance changing layer and a second electrode layer. The first electrode layer is arranged on the thermally conductive layer. The heat preserving element is arranged on the first electrode layer and forms a through-hole. A part of a surface of the first electrode layer is exposed to the through-hole. The resistance changing layer extends from the part of the surface of the first electrode layer to a surface of the heat preserving element that is located outside the through-hole. The second electrode layer is arranged on the resistance changing layer.

Abstract: In a method of manufacturing a semiconductor device, a first contact hole is formed in one or more dielectric layers disposed over a source/drain region or a gate electrode. An adhesive layer is formed in the first contact hole. A first metal layer is formed on the adhesive layer in the first contact hole. A silicide layer is formed on an upper surface of the first metal layer. The silicide layer includes a same metal element as the first metal layer.

Abstract: A processor for signal reshaping receives an input image with an input bit depth. Block-based standard deviations are computed. The input codewords are divided into codeword bins and each bin is assigned a standard deviation value. For each bin, a standard deviation to bit-depth function is applied to the bin values to generate minimal bit depth values for each codeword bin. An output codeword mapping function is generated based on the input bit depth, a target bit depth, and the minimal bit depth values. The codeword mapping function is applied to the input image to generate an output image in the target bit depth.

Abstract: A piezoelectric actuator includes a suspension plate, a piezoelectric ceramic plate, an outer frame and a bracket. The suspension plate is permitted to undergo a curvy vibration from a middle portion to a periphery portion. The piezoelectric ceramic plate is attached on the suspension plate. When a voltage is applied to the piezoelectric ceramic plate, the suspension plate is driven to undergo the curvy vibration. The outer frame is arranged around the suspension plate. The bracket is connected between the suspension plate and the outer frame for elastically supporting the suspension plate, and includes an intermediate part formed in a vacant space between the suspension plate and the outer frame and in parallel with the outer frame and the suspension plate, a first connecting part arranged between the intermediate part and the suspension plate, and a second connecting part arranged between the intermediate part and the outer frame.

Abstract: A cleaning apparatus includes a combing unit including a series of spaced protrusions or teeth extending into a cleaning roller for preventing build up and removing debris (such as hair, string, and the like). The protrusions extend along a substantial portion of the cleaning roller and extend partially into the cleaning roller to intercept the debris as it passes around the roller. The protrusions have angled leading edges that are not aligned with a rotation center of the cleaning roller and are directed into or against a direction of rotation of the cleaning roller. The combing unit and protrusions have a shape and configuration designed to facilitate debris removal from the cleaning roller with minimal impact on the operation of the cleaning apparatus. The cleaning apparatus may include a surface cleaning head of an upright vacuum cleaner or sweeper or a robotic vacuum cleaner.

Abstract: The present disclosure relates to a semiconductor device. The semiconductor device includes a substrate, a first doping region, a second doping region, a third doping region, a first transient block unit and a second transient block unit. The first doping region is in the substrate. The second doping region is in the first doping region. The third doping region is in the first doping region. The first transient block unit is electrically connected to the second doping region. The second transient block unit is electrically connected between the third doping region and the first transient block unit.

Abstract: An array substrate, a touch display panel and a touch display device are provided to realize the In-cell touch technology in the AMOLED displays. The array substrate includes a base substrate (1) having a plurality of pixel units formed by intersecting data lines (7) and gate lines (2) provided on the base substrate (1), each pixel unit comprises a bottom emission type OLED device and at least one TFT, and the OLED device includes a transparent anode (13). The array substrate further includes a plurality of first electrodes (10) disposed parallel with and in a same layer as the data lines (7) and a plurality of second electrodes (14) disposed parallel with the gate lines (2) and in a same layer as the anode (13). At least one first electrode (10) constitutes a touch driving line (20), and at least one second electrode (14) constitutes a touch sensing line (21).

Abstract: The disclosure relates to methods for treating a subject suffering from a burn injury or associated complications by administering to the subject an effective amount of an aromatic-cationic peptide. For example, a burn injury may be associated with distant pathophysiological effects, such as hypermetabolism, skeletal muscle dysfunction, and organ damage. The disclosure also relates to methods for protecting a subject from a burn injury by administering an effective amount of an aromatic-cationic peptide to a subject at risk of a burn injury.

Abstract: A resettable linear resonant actuator is disclosed, including: a magnet set, a coil and a first magnetic induction element. The magnet set includes first and second magnets. The first side of first magnet contacts the second side of second magnet. The top and bottom surfaces of first and second magnets are at the same level respectively. The first magnet has N pole at top surface and S pole at bottom, while the second magnet has the opposite. The first coil is disposed above or below magnet set and corresponds to contact between the first magnet and second magnet. The first magnetic induction element is disposed at first coil and corresponds to the contact between first magnet and second magnet. With electricity running in first coil, the movable part executes simple harmonic motion by Lorentz force, with electricity off, the movable part returns to the original point by restoration force.

Abstract: A TSV structure includes a substrate comprising at least a TSV opening formed therein, a conductive layer disposed in the TSV opening, and a bi-layered liner disposed in between the substrate and the conductive layer. More important, the bi-layered liner includes a first liner and a second liner, and a Young's modulus of the first liner is different from a Young's modulus of the second liner.

Abstract: Metal-sulfur energy storage devices also comprising new redox mediator compounds are described.

Abstract: An illuminated keyswitch includes a base, a keycap, a lift mechanism, and a light source. The keycap includes a cap body and a light guiding rod. The lift mechanism is connected to between the light guiding rod and the base, such that the keycap can vertically move relative to the base through the lift mechanism. The light source is disposed between the light guiding rod and the base and emits light toward the light guiding rod. The light enters the light guiding rod through an end portion of the light guiding rod and then emits out the light guiding rod from another end portion of the light guiding rod and a side surface adjacent to the another end portion toward the cap body. Thereby, the whole cap body can receives relatively uniform back light.

Abstract: A mortise and tenon joint for furniture, includes a mortise piece and a tenon piece. The mortise piece includes a cut-out region. The cut-out region includes a surface. A mortise is located at the cut-out region. A tenon piece includes a tenon sized to fit within the mortise. The tenon piece has a surface that matches the surface of the cut-out region so that when the tenon is within the mortise, the tenon piece can be rotated into a first orientation so that the surface of the tenon piece is flush with the surface of the cut-out region, and the tenon piece can be rotated into a second orientation so that the surface of the tenon piece is not flush with the surface of the cut-out region.

Abstract: Filter media is described that includes a filtration substrate having a first side and a second side, and constructed for filtering a fluid by flow of the fluid therethrough from the first side to the second side or from the second side to the first side. The filtration substrate has a first edge and a second edge, and a first end and a second end, wherein the filtration substrate has a machine direction extending from the first end to the second end, and a cross direction extending from the first side to the second side. The filtration substrate includes a plurality of corrugations located in the cross direction and extending in the machine direction. The plurality of corrugations include a plurality of first crests formed along the first side of the filtration substrate and a plurality of second crests formed along the second side of the filtration substrate.

Abstract: Semiconductor devices, FinFET devices and methods of forming the same are disclosed. One of the semiconductor devices includes a substrate, a gate over the substrate and a gate dielectric layer between the gate and the substrate. The gate dielectric layer includes an oxide-inhibiting layer having a dielectric constant greater than about 8 and being in an amorphous state.

Abstract: A method of detecting power reset of a server includes: after receiving an event signal, determining whether or not to initialize a random access memory (RAM) of a baseboard management controller (BMC) of the server based on the event signal thus received, and initializing the RAM when it is determined to initialize the same; determining whether a protocol error event has occurred according to a flag value of a power reset flag stored in the RAM; determining whether malfunction of a processor unit of the BMC has occurred when it is determined that the protocol error event has not occurred; and determining that a power reset event has occurred when it is determined that malfunction of the processor unit has not occurred.

Abstract: A method, apparatus and computer program products are provided for determining an entry finder from a plurality of merge points of a bounding box for optimal performance of differential group pattern match routing. One example method includes identifying each of a plurality of merge point candidates, performing a routability determination process, the results of the routability determination process comprising a remaining subset of the plurality of merge point candidates, routing each remaining merge point from the remaining subset of the plurality of merge point candidates, calculating a routing cost for each remaining merge point from the remaining subset of the plurality of merge point candidates, and determining a merge point having a lowest calculated cost.