Patents by Inventor Ming-Fei Lang

Ming-Fei Lang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160362689
    Abstract: A significant challenge in cancer research field is to define molecular features that distinguish cancer stem cells from normal stem cells. In this study, microRNA (miRNA) expression profiles in human glioblastoma stem cells were compared to that of normal neural stem cells using combined microarray and deep sequencing analyses. These studies led to the identification of several miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells. Characterizing the role of these miRNAs in glioblastoma stem cells is important for the development of miRNA-based therapies that specifically target tumor stem cells, but spare normal stem cells.
    Type: Application
    Filed: April 18, 2016
    Publication date: December 15, 2016
    Inventors: Yanhong SHI, Ming-Fei LANG, Chunnian ZHAO
  • Patent number: 9315809
    Abstract: A significant challenge in cancer research field is to define molecular features that distinguish cancer stem cells from normal stem cells. In this study, microRNA (miRNA) expression profiles in human glioblastoma stem cells were compared to that of normal neural stem cells using combined microarray and deep sequencing analyzes. These studies led to the identification of several miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells. Characterizing the role of these miRNAs in glioblastoma stem cells is important for the development of miRNA-based therapies that specifically target tumor stem cells, but spare normal stem cells.
    Type: Grant
    Filed: August 29, 2013
    Date of Patent: April 19, 2016
    Assignee: CITY OF HOPE
    Inventors: Yanhong Shi, Ming-Fei Lang, Chunnian Zhao
  • Publication number: 20140088170
    Abstract: A significant challenge in cancer research field is to define molecular features that distinguish cancer stem cells from normal stem cells. In this study, microRNA (miRNA) expression profiles in human glioblastoma stem cells were compared to that of normal neural stem cells using combined microarray and deep sequencing analyses. These studies led to the identification of several miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells. Characterizing the role of these miRNAs in glioblastoma stem cells is important for the development of miRNA-based therapies that specifically target tumor stem cells, but spare normal stem cells.
    Type: Application
    Filed: August 29, 2013
    Publication date: March 27, 2014
    Inventors: Yanhong Shi, Ming-Fei Lang, Chunnian Zhao