Patents by Inventor Mingle Cai

Mingle Cai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Energy-providing bone-repair degradable porous scaffold, preparation method thereof, and application thereof
    Patent number: 9855366
    Abstract: The invention discloses an energy-providing bone-repair degradable porous scaffold, a preparation method thereof, and an application thereof. The invention obtains an energy-based biomaterial solution by compositing gelatin, a polyatomic acid and derivatives thereof, a dibasic alcohol and derivatives thereof, and a tribasic alcohol and derivatives thereof in a chemical cross-linking manner by using diisocyanate, and further obtains a porous scaffold through a drying method. The porous scaffold can avoid the problem of an acidic microenvironment caused by in vivo implantation of the existing biomaterial and keep the activity of an osteoblast cell, thereby improving the rate of repairing the damaged bone tissue with the energy-based biomaterial. The porous scaffold of the invention can be used as a filling material for bone repair in a surgical operation.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: January 2, 2018
    Assignee: Huazhong University of Science and Technology
    Inventors: Shengmin Zhang, Mingle Cai, Haoming Liu
  • Energy-Providing Bone-Repair Degradable Porous Scaffold, Preparation Method Thereof, and Application Thereof
    Publication number: 20170246343
    Abstract: The invention discloses an energy-providing bone-repair degradable porous scaffold, a preparation method thereof, and an application thereof. The invention obtains an energy-based biomaterial solution by compositing gelatin, a polyatomic acid and derivatives thereof, a dibasic alcohol and derivatives thereof, and a tribasic alcohol and derivatives thereof in a chemical cross-linking manner by using diisocyanate, and further obtains a porous scaffold through a drying method. The porous scaffold can avoid the problem of an acidic microenvironment caused by in vivo implantation of the existing biomaterial and keep the activity of an osteoblast cell, thereby improving the rate of repairing the damaged bone tissue with the energy-based biomaterial. The porous scaffold of the invention can be used as a filling material for bone repair in a surgical operation.
    Type: Application
    Filed: April 15, 2016
    Publication date: August 31, 2017
    Inventors: Shengmin Zhang, Mingle Cai, Haoming Liu