Patents by Inventor Mingle LI

Mingle LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230344242
    Abstract: A method for automatic adjustment of a power grid operation mode based on reinforcement learning is provided. An expert system for automatic adjustment is designed, which relies on the control sequence of thermal power units, enabling automatic decision-making for power grid operation mode adjustment. A sensitivity matrix is extracted from the historical operating data of the power grid, from which a foundational thermal power unit control sequence is derived. An overload control strategy for lines within the expert system is devised. A reinforcement learning model optimizes the thermal power unit control sequence, which refines the foundational thermal power unit control sequence and provides the expert system with the optimized control sequence for automatic decision-making in power grid operation mode adjustment. This method offers a solution to balancing and absorption challenges brought about by fluctuations on both the supply and demand sides in high-proportion renewable energy power systems.
    Type: Application
    Filed: April 24, 2023
    Publication date: October 26, 2023
    Inventors: TAO DING, MINGLE LI, SHUAI LI, ZHIQIN TIAN, YIXING GAO
  • Patent number: 11639360
    Abstract: Disclosed are an oxazine compound and an application thereof. The oxazine compound has a structure of a general formula F. The oxazine compound described in the disclosure is a photo/acoustic dynamic active organic molecule with near-infrared absorption-emission function as well as photosensitivity and acoustic sensitivity. Maximum absorption and emission wavelengths of the compound are both greater than 660 nanometers, and a triplet-state conversion rate of the compound is high; and under illumination or ultrasound, the compound can produce reactive oxygen species with high efficiency, which has a good killing effect on cancer cells and cancer tissues, and almost has no toxic or side effects on normal tissues while achieving photo/acoustic dynamic therapy on tumors.
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: May 2, 2023
    Assignees: DALIAN UNIVERSITY OF TECHNOLOGY, DALIAN CHROMAS BIOSCIENCE CO., LTD
    Inventors: Jiangli Fan, Qichao Yao, Haidong Li, Yana Bian, Mingle Li, Jingyun Wang, Xiaojun Peng
  • Patent number: 11504428
    Abstract: A photosensitizer and derivative, application thereof. The photosensitizer has the structure of general formula I, wherein X is S or Se, Y is organic or inorganic ion, R1 and R2 are independently selected from H, alkyl, alkoxy, alkyl amido, alkyl azide and the like; R3 is selected from H, alkyl, alkoxy, amino sulfonyl, hydroxyl, carboxyl and the like, and L1 is a linker selected from —(CH2)n1— or —(CH2CH2O)n2—. The derivatives are molecular medicines with drug molecules of anticancer and chemotherapy or tumor targeting function connected to the said photosensitizer. The photosensitizer has excellent near infrared characteristics and low dark toxicity and is used in the field of photodynamic tumor therapy. The introduction of benzophenothiazine or benzophenoselenazine into derivatives with tumor-targeting function could improve the specific uptake of photosensitizer in tumor tissues.
    Type: Grant
    Filed: November 24, 2017
    Date of Patent: November 22, 2022
    Assignees: DALIAN UNIVERSITY OF TECHNOLOGY, DALIAN CHROMAS BIOSCTENCE CO., LTD
    Inventors: Xiaojun Peng, Mingle Li, Jiangli Fan, Qichao Yao, Jianjun Du, Saran Long, Jingyun Wang
  • Publication number: 20210188875
    Abstract: Disclosed are an oxazine compound and an application thereof. The oxazine compound has a structure of a general formula F. The oxazine compound described in the disclosure is a photo/acoustic dynamic active organic molecule with near-infrared absorption-emission function as well as photosensitivity and acoustic sensitivity. Maximum absorption and emission wavelengths of the compound are both greater than 660 nanometers, and a triplet-state conversion rate of the compound is high; and under illumination or ultrasound, the compound can produce reactive oxygen species with high efficiency, which has a good killing effect on cancer cells and cancer tissues, and almost has no toxic or side effects on normal tissues while achieving photo/acoustic dynamic therapy on tumors.
    Type: Application
    Filed: April 22, 2019
    Publication date: June 24, 2021
    Inventors: Jiangli FAN, Qichao YAO, Haidong LI, Yana BIAN, Mingle LI, Jingyun WANG, Xiaojun PENG
  • Publication number: 20210030873
    Abstract: A photosensitizer and derivative, application thereof. The photosensitizer has the structure of general formula I, wherein X is S or Se, Y is organic or inorganic ion, R1 and R2 are independently selected from H, alkyl, alkoxy, alkyl amido, alkyl azide and the like; R3 is selected from H, alkyl, alkoxy, amino sulfonyl, hydroxyl, carboxyl and the like, and L1 is a linker selected from —(CH2)n1— or —(CH2CH2O)n2—. The derivatives are molecular medicines with drug molecules of anticancer and chemotherapy or tumor targeting function connected to the said photosensitizer. The photosensitizer has excellent near infrared characteristics and low dark toxicity and is used in the field of photodynamic tumor therapy. The introduction of benzophenothiazine or benzophenoselenazine into derivatives with tumor-targeting function could improve the specific uptake of photosensitizer in tumor tissues.
    Type: Application
    Filed: November 24, 2017
    Publication date: February 4, 2021
    Applicants: DALIAN UNIVERSITY OF TECHNOLOGY, DALIAN CHROMAS BIOSCIENCE CO., LTD
    Inventors: Xiaojun PENG, Mingle LI, Jiangli FAN, Qichao YAO, Jianjun DU, Saran LONG, Jingyun WANG