Abstract: The present invention discloses a fire extinguishing system for a battery pack, including a detection control apparatus, a fire suppression apparatus, and a hydrant water extinguishing apparatus. The detection control apparatus is disposed inside or outside a battery pack. The fire suppression apparatus and the hydrant water extinguishing apparatus are disposed outside the battery pack. The detection control apparatus is connected to the fire suppression apparatus. The hydrant water extinguishing apparatus is connected to the fire suppression apparatus. Beneficial effects: It is ensured that initial fire can be suppressed and later reignition can be resolved, so that fire extinguishing is adequate. Fire is directly extinguished at a core position inside the battery pack. An exhaust filter device gains valuable time after initial fire extinguishing.

Abstract: The present invention discloses a battery pack charging system, comprising battery packs and a charging cabinet, a nitrogen replacement device is arranged inside the charging cabinet, the charging cabinet provides charging and nitrogen filling for the battery packs, wherein: there is a gas-filling protective device arranged between the nitrogen replacement device and the battery packs, and the gas-filling protective device is used to regulate the gas-filling flow of nitrogen automatically. Also disclosed is a charging method of the battery pack charging system.

Abstract: The present invention discloses a fire extinguishing system for a battery pack, including a detection control apparatus, a fire suppression apparatus, and a hydrant water extinguishing apparatus. The detection control apparatus is disposed inside or outside a battery pack. The fire suppression apparatus and the hydrant water extinguishing apparatus are disposed outside the battery pack. The detection control apparatus is connected to the fire suppression apparatus. The hydrant water extinguishing apparatus is connected to the fire suppression apparatus. Beneficial effects: It is ensured that initial fire can be suppressed and later reignition can be resolved, so that fire extinguishing is adequate. Fire is directly extinguished at a core position inside the battery pack. An exhaust filter device gains valuable time after initial fire extinguishing.

Abstract: The present application relates to a crystalline sulfamide compound, and in particular relates to a crystalline (S)—N—((S)-1-(2-chlorphenyl)-2-((3,3-difluorocyclobutyl)amido)-2oxoethyl)-2-(4-cyanopyridin-2-base)-N-(3-fluorophenyl)-isothiazolidine-3-formamide 1,1-dioxide, and a preparation method therefor, a crystalline composition, a pharmaceutical composition and uses thereof. An X-ray powder diffraction spectrum of a crystalline hydrate of formula II of the present application has diffraction peaks at positions of about 14.40°, 20.28°, 20.94°, 22.02°, and 24.46°, represented by 2?. The crystalline hydrate of formula II of the present application has good IDH1 inhibitory activity and performs high stability, and therefore has advantages in physical property, safety and metabolic stability, and has high medicine value.

Abstract: A method for identifying the state of breast cancer status in human subjects, comprising: (1) collecting biological samples from the human subjects; (2) detecting methylation level of biomarker genes in the biological samples, wherein the biomarker genes are one or more selected from the following genes: APC, BRCA1, CCND2, CST6, GP5, GSTP1, PITX2, RARB, RASSF1A and SOX17; and (3) comparing the methylation level detected in step (2) with the normal methylation level of the corresponding biomarker gene in the colony to determine the state of breast cancer in human subjects. Further provided is a kit for identifying the state of breast cancer in human subjects.

Abstract: A method for identifying the gastric cancer status of a subject, comprising: 1) collecting a biological sample from the subject; 2) detecting methylation level of a biomarker gene in the biological sample, wherein the biomarker gene is selected from one or more of the following genes: CDH1, DAPK, PAX5, RASSF1A, Reprimo, RNF180, RUNX3, SDC2, Septin9 and TCF4; and 3) comparing the detected methylation level from step 2) with a normal methylation level of a corresponding biomarker gene in a population to determine the gastric cancer status in the subject. Also provided is a kit for identifying the gastric cancer status of a subject. The method and the kit provided herein provide a new way for fast, reliable and accurate prediction, diagnosis and evaluation of gastric cancer.

Abstract: A coupling box of a rail vehicle, including a fixed portion fixedly mounted on a vehicle body and a movable portion connecting to a coupler and draft gear; the movable portion is connected to an inner end of the fixed portion by means of a constant-force connecting member, the constant-force connecting member is broken when the coupler and draft gear pushes the movable portion to move inwardly at the time of a collision, so that the movable portion and the fixed portion are able to be separated from each other.

Abstract: A method for identifying the status of a colorectal cancer in a subject, comprising: 1) collecting a biological sample from the subject; detecting a methylation level of biomarker genes in the biological sample, wherein the biomarker genes are selected from one or more the following genes: ALX4, BCAT1, BMP3, IKZF1, NDRG4, NPTX2, RARB, SDC2, Septin9 and VIM; and 3) comparing the methylation level detected in step 2) with a normal methylation level of corresponding biomarker genes in a population, so as to determine the status of the colorectal cancer in the subject. Also provided is a kit for identifying the status of a colorectal cancer status in a subject.

Abstract: A method for identifying lung cancer status in a subject comprising: collecting a biological sample from the subject; detecting the methylation level of a biomarker gene in the biological sample, the biomarker gene being one or more selected from the following genes: BCAT1, CDH1, DCLK1, FOXL2, HOXA9, PTGER4, RARB, RASSF1A, Septin9, and SHOX2; and comparing the detected methylation levels with a normal methylation level of a corresponding biomarker gene in the population to determine the lung cancer status in the subject. Also provided herein is a kit for identifying lung cancer status in a subject.

Abstract: The present application relates to a crystalline sulfamide compound, and in particular relates to a crystalline (S)-N-((S)-1-(2-chlorphenyl)-2-((3,3-difluorocyclobutyl)amido)-2oxoethyl)-2-(4-cyanopyridin-2-base)-N-(3-fluorophenyl)-isothiazolidine-3-formamide 1,1-dioxide, and a preparation method therefor, a crystalline composition, a pharmaceutical composition and uses thereof. An X-ray powder diffraction spectrum of a crystalline hydrate of formula II of the present application has diffraction peaks at positions of about 14.40°, 20.28°, 20.94°, 22.02°, and 24.46°, represented by 2?. The crystalline hydrate of formula II of the present application has good IDH1 inhibitory activity and performs high stability, and therefore has advantages in physical property, safety and metabolic stability, and has high medicine value.

Abstract: A media playing device and a media playing method are proposed. An interface module of the media playing device is coupled with an external media device and information handshaking is established therebetween such that media contents stored in the external media device can be identified by an identifying module of the media playing device. A user interface is created by a user interface module of the media playing device, which allows a user to input an operating instruction. An information processing module of the media playing device processes media content related information according to the operating instruction inputted by the user. In addition, a charging interface of the media playing device is coupled with a charging terminal of the external media device such that a charging module of the media playing device can charge the external media device when power left in the external media device is not enough.