Abstract: A pyrimidine-2,4-diamine compound and a preparation method and application thereof are provided. The pyrimidine-2,4-diamine compound of the present disclosure can be used in the research of biological or pharmacological phenomena and cathepsin C-involved signal pathway transduction and the evaluation of novel cathepsin C inhibitors. The pyrimidine-2,4-diamine compound is subjected to the screening of anti-cathepsin C activity in vitro and in vivo and proved to have strong inhibitory activity on cathepsin C. The pyrimidine-2,4-diamine compound is subjected to the screening of anti-NSP activity in vivo and proved to have strong inhibitory activity on NSP. The pyrimidine-2,4-diamine compound is subjected to the screening of anti-inflammatory activity in vivo and proved to have an effective therapeutic effect on inflammatory disease models. Meanwhile, the pyrimidine-2,4-diamine compound shows low toxicity and exhibits good application prospect.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer-readable media that utilize machine-learning models to classify content items and automatically organize the content items within a file structure according to their content item classifications. For instance, a content item classification system generates one or more content item classification models to determine classifications for content items and/or folders. In some instances, the classification system detects when new content items are added to a smart folder, determines destination folders to which the content items belong based on classifying the content items, and automatically moves the content items accordingly. In various instances, the classification system generates and utilizes a classification model to organize content items into dynamically-generated folders.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer-readable media that utilize machine-learning models to classify content items and automatically organize the content items within a file structure according to their content item classifications. For instance, a content item classification system generates one or more content item classification models to determine classifications for content items and/or folders. In some instances, the classification system detects when new content items are added to a smart folder, determines destination folders to which the content items belong based on classifying the content items, and automatically moves the content items accordingly. In various instances, the classification system generates and utilizes a classification model to organize content items into dynamically-generated folders.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer-readable media that utilize machine-learning models to classify content items and automatically organize the content items within a file structure according to their content item classifications. For instance, a content item classification system generates one or more content item classification models to determine classifications for content items and/or folders. In some instances, the classification system detects when new content items are added to a smart folder, determines destination folders to which the content items belong based on classifying the content items, and automatically moves the content items accordingly. In various instances, the classification system generates and utilizes a classification model to organize content items into dynamically-generated folders.

Abstract: According to at least one example of the disclosure, a power amplifier system is provided comprising an amplifying transistor configured to amplify a radio frequency signal, a bias circuit configured to provide a bias voltage to the amplifying transistor, and a clamp circuit for protecting the power amplifier system by absorbing a current flowing through the amplifying transistor when the clamp circuit is switched on. The clamp circuit is connected at a bias node between the bias circuit and the amplifying transistor and includes a clamp transistor and a clamp diode, the clamp diode having one end connected to a collector of the clamp transistor at the bias node and another end connected to a base of the clamp transistor.

Abstract: Asymmetric Doherty power amplifiers are disclosed. In certain embodiments, a Doherty power amplifier includes a carrier amplifier that generates a radio frequency carrier signal based on amplifying a radio frequency input signal, a peaking amplifier that generates a radio frequency peaking signal based on amplifying the radio frequency input signal, and a phase shifting and combining circuit configured to combine the radio frequency carrier signal and the radio frequency peaking signal to generate a radio frequency output signal. The peaking amplifier has an amplifier size that is smaller than an amplifier size of the carrier amplifier.

Abstract: Disclosed are a control method for a bidirectional DC converter, a control module for a bidirectional DC converter, a bidirectional DC converter, and a non-transitory computer-readable storage medium. The control method includes: determining an operating mode of the bidirectional DC converter according to an input voltage and an output voltage; respectively determining a duty cycle of a drive signal of the first switch transistor, a duty cycle of a drive signal of the second switch transistor, a duty cycle of a drive signal of the third switch transistor, and a duty cycle of a drive signal of the fourth switch transistor according to the operating mode of the bidirectional DC converter; and providing drive signals to gates of the first switch transistor, the second switch transistor, the third switch transistor and the fourth switch transistor respectively.

Abstract: A ripple detection device and a ripple suppression device. The ripple detection device includes: a ripple sampling unit, at least two DC sampling units, and a digital signal processing unit; the ripple sampling unit outputs a first voltage signal at an output port of a non-isolated DC/DC bidirectional energy conversion unit to the digital signal processing unit; the DC sampling unit outputs a first DC signal in a second voltage signal at a connected port of the non-isolated DC/DC bidirectional energy conversion unit to the digital signal processing unit and blocks an AC signal in the second voltage signal to be output to the digital signal processing unit; the digital signal processing unit determines a ripple noise signal at the output port of the non-isolated DC/DC bidirectional energy conversion unit according to the first voltage signal and the first DC signal.

Abstract: Asymmetric Doherty power amplifiers are disclosed. In certain embodiments, a Doherty power amplifier includes a carrier amplifier that generates a radio frequency carrier signal based on amplifying a radio frequency input signal, a peaking amplifier that generates a radio frequency peaking signal based on amplifying the radio frequency input signal, and a phase shifting and combining circuit configured to combine the radio frequency carrier signal and the radio frequency peaking signal to generate a radio frequency output signal. The carrier amplifier and the peaking amplifier have asymmetric amplifier sizes.

Abstract: The disclosure discloses a phosphorus-nitrogen-zinc two-dimensional supramolecular coated molybdenum disulfide hybrid flame retardant and application thereof, and belongs to the technical field of halogen-free flame retardant. Components of the phosphorus-nitrogen-zinc two-dimensional supramolecular coated molybdenum disulfide hybrid material in the disclosure include, by weight, 1-2 parts of molybdenum disulfide, 1-1.5 parts of zinc salt, 5-8 parts of a nitrogen-containing compound and 5-10 parts of a phosphorus-containing compound. As a flame retardant, the hybrid material of the disclosure effectively exerts an organic-inorganic synergistic flame retardant effect; the flame retardant efficiency of molybdenum disulfide is improved; the addition amount of the flame retardant in a matrix is reduced; the mechanical properties of the matrix can be improved at the same time; and the material has a very good application prospect.

Abstract: A method for displaying a prompt text is provided, which belongs to the field of computer technologies. The method includes: collecting content information generated in a speaking process of a target object; obtaining identification information by identifying the content information, the identification information indicating speaking progress of the target object; and displaying the prompt text based on the identification information, so that a prompt text fragment as highlighted in the prompt text matches the speaking progress of the target object.

Abstract: Disclosed are a control method for a bidirectional DC converter, a control module for a bidirectional DC converter, a bidirectional DC converter, and a non-transitory computer-readable storage medium. The control method includes: determining an operating mode of the bidirectional DC converter according to an input voltage and an output voltage; respectively determining a duty cycle of a drive signal of the first switch transistor, a duty cycle of a drive signal of the second switch transistor, a duty cycle of a drive signal of the third switch transistor, and a duty cycle of a drive signal of the fourth switch transistor according to the operating mode of the bidirectional DC converter; and providing drive signals to gates of the first switch transistor, the second switch transistor, the third switch transistor and the fourth switch transistor respectively.

Abstract: A ripple detection device and a ripple suppression device. The ripple detection device includes: a ripple sampling unit, at least two DC sampling units, and a digital signal processing unit; the ripple sampling unit outputs a first voltage signal at an output port of a non-isolated DC/DC bidirectional energy conversion unit to the digital signal processing unit; the DC sampling unit outputs a first DC signal in a second voltage signal at a connected port of the non-isolated DC/DC bidirectional energy conversion unit to the digital signal processing unit and blocks an AC signal in the second voltage signal to be output to the digital signal processing unit; the digital signal processing unit determines a ripple noise signal at the output port of the non-isolated DC/DC bidirectional energy conversion unit according to the first voltage signal and the first DC signal.

Abstract: According to at least one example of the disclosure, a power amplifier system is provided comprising an amplifying transistor configured to amplify a radio frequency signal, a bias circuit configured to provide a bias voltage to the amplifying transistor, and a clamp circuit for protecting the power amplifier system by absorbing a current flowing through the amplifying transistor when the clamp circuit is switched on. The clamp circuit is connected at a bias node between the bias circuit and the amplifying transistor and includes a clamp transistor and a clamp diode, the clamp diode having one end connected to a collector of the clamp transistor at the bias node and another end connected to a base of the clamp transistor.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer-readable media that utilize machine-learning models to classify content items and automatically organize the content items within a file structure according to their content item classifications. For instance, a content item classification system generates one or more content item classification models to determine classifications for content items and/or folders. In some instances, the classification system detects when new content items are added to a smart folder, determines destination folders to which the content items belong based on classifying the content items, and automatically moves the content items accordingly. In various instances, the classification system generates and utilizes a classification model to organize content items into dynamically-generated folders.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer-readable media that utilize machine-learning models to classify content items and automatically organize the content items within a file structure according to their content item classifications. For instance, a content item classification system generates one or more content item classification models to determine classifications for content items and/or folders. In some instances, the classification system detects when new content items are added to a smart folder, determines destination folders to which the content items belong based on classifying the content items, and automatically moves the content items accordingly. In various instances, the classification system generates and utilizes a classification model to organize content items into dynamically-generated folders.

Abstract: A pyrimidine-2,4-diamine compound and a preparation method and application thereof are provided. The pyrimidine-2,4-diamine compound of the present disclosure can be used in the research of biological or pharmacological phenomena and cathepsin C-involved signal pathway transduction and the evaluation of novel cathepsin C inhibitors. The pyrimidine-2,4-diamine compound is subjected to the screening of anti-cathepsin C activity in vitro and in vivo and proved to have strong inhibitory activity on cathepsin C. The pyrimidine-2,4-diamine compound is subjected to the screening of anti-NSP activity in vivo and proved to have strong inhibitory activity on NSP. The pyrimidine-2,4-diamine compound is subjected to the screening of anti-inflammatory activity in vivo and proved to have an effective therapeutic effect on inflammatory disease models. Meanwhile, the pyrimidine-2,4-diamine compound shows low toxicity and exhibits good application prospect.

Abstract: Asymmetric Doherty power amplifiers are disclosed. In certain embodiments, a Doherty power amplifier includes a carrier amplifier that generates a radio frequency carrier signal based on amplifying a radio frequency input signal, a peaking amplifier that generates a radio frequency peaking signal based on amplifying the radio frequency input signal, and a phase shifting and combining circuit configured to combine the radio frequency carrier signal and the radio frequency peaking signal to generate a radio frequency output signal. The carrier amplifier and the peaking amplifier have asymmetric amplifier sizes.

Abstract: A Doherty power amplifier comprising: an input configured to receive an input signal to be amplified and to split the input signal into a first portion and a second portion, the input signal having an operating frequency; a carrier amplifier path coupled to the input to receive the first portion, the carrier amplifier path including a carrier amplifier coupled to a differential inverter, the carrier amplifier being configured to amplify the first portion and provide an amplified first portion to the differential inverter, the differential inverter having a capacitance configured to make the differential inverter behave as a short circuit at odd harmonics of the operating frequency, the capacitance coupling a first path and a second path of the differential inverter in parallel; and a peaking amplifier path coupled to the input to receive the second portion and comprising a peaking amplifier configured to amplify the second portion.

Abstract: The present invention relates to the field of synthetic medicinal chemistry and provides a series of novel diaryl-?-lactam compounds having significant anti-tumor activity, and the pharmaceutical use thereof. The present invention also comprises the use of these compounds, pharmaceutical salts, and pharmaceutical composition thereof for preparing a pharmaceutical for the prevention or treatment of tumor-associated disease. The diaryl-?-lactam compounds of the present invention have the following general formula (I).