Abstract: Provided are a centromere protein CENP-M small molecule inhibitor cenpemlin, and a preparation method therefor and the use thereof. A small molecule compound cenpemlin is obtained by means of analyzing the protein plane information of the fine structures of CENP-M and CENP-L and performing targeted screening. The results of biochemical and cytological experiments all indicate that cenpemlin inhibits the proliferation of cancer cells by means of interfering with the interaction between CENP-M and CENP-L, thereby providing a new compound for analyzing and interfering with the rapid proliferation of cancer cells.

Abstract: A water storage box and a refrigerator; the water storage box includes a box body and a front panel provided on a front end surface of the box body, and further includes: a locking structure including a locking part and a fitting part, one of the locking part and the fitting part being provided on a rear surface of the front panel, the other of the locking part and the fitting part being provided on the front end surface, and the locking structure being provided near a first side of the front end surface; at least one overturning structure provided between the rear surface and the front end surface, the at least one overturning structure being provided close to a second side of the front end surface, and the first side being opposite to the second side.

Abstract: Disclosed are a door body for a refrigerator and a refrigerator with the same. The refrigerator includes a cabinet defining a storage compartment with a compartment opening, and the door body includes an inner door, an outer door and a storage box. The inner door is arranged at a position corresponding to the compartment opening on an outer side of the storage compartment, and is used to open and close the compartment opening. The outer door is arranged at a side of the inner door away from the storage compartment. The storage box is fixed to a side of the inner door close to the storage compartment; one end of the storage box close to the outer door has a storage opening, and an area of the inner door corresponding to the storage opening is provided with an inner door opening. The door body reduces the loss of cooling energy.

Abstract: A method for manufacturing a semiconductor structure includes: providing a substrate including a transistor structure; forming a laminated structure on the substrate, the laminated structure including a dielectric layer and an insulating layer which are sequentially stacked in a thickness direction of the substrate, and the insulating layer being arranged on a side, away from the substrate, of the dielectric layer; forming a through hole penetrating through the laminated structure in the laminated structure to expose a source/drain of the transistor structure; and etching at least part of a side wall of the through hole located in the dielectric layer to form a conductive hole in the insulating layer and the dielectric layer. An aperture size of a medial part of the conductive hole is greater than an aperture size of each of both ends of the conductive hole.

Abstract: A water storage box and a refrigerator; the water storage box includes a box body and a front panel provided on a front end surface of the box body, and further includes: a locking structure including a locking part and a fitting part, one of the locking part and the fitting part being provided on a rear surface of the front panel, the other of the locking part and the fitting part being provided on the front end surface, and the locking structure being provided near a first side of the front end surface; at least one overturning structure provided between the rear surface and the front end surface, the at least one overturning structure being provided close to a second side of the front end surface, and the first side being opposite to the second side.

Abstract: A method and apparatus for processing character image data are provided. A specific embodiment of the method can include: acquiring a video including character images of a first character as first data, and acquiring a video including character images of a second character as second data, the video including character images of the first character including a plurality of types of movement-state images; replacing a head image extracted from the first data with a head image extracted from the second data; replacing a face extracted from the first data with a face extracted from the second data; and replacing the face in the replaced head image with the replaced face to obtain a target head image.

Abstract: The present application discloses a storage box, comprising an enclosure, a storage box body, a pivot shaft connected to the enclosure and the storage box body, an elastic element disposed between the pivot shaft and the enclosure, and a locking device, wherein the elastic element always provides a driving force driving the storage box body to turn outwards the enclosure about the pivot shaft; the locking device comprises a locking portion disposed on the enclosure, and a fitting portion which is disposed on the storage box body and push-fitted with the locking portion. The storage box body can automatically turn without a handle being disposed, thereby expanding the space for storing items.

Abstract: A method for synthesizing a figure of a virtual object includes: obtaining a figure image of the virtual object, and original face images corresponding to a speech segment; extracting a first face key point of the face of the virtual object, and a second face key point of each of the original face images; processing the first face key point to generate a position and posture information of a first three-dimensional 3D face; processing each second face key point to generate vertex information of a second 3D face; generating a target face image corresponding to each original face image based on the position and the posture information of the first 3D face and the vertex information of each second 3D face; and synthesizing a speaking figure segment of the virtual object, corresponding to the speech segment, based on the figure image of the virtual object and each target face image.

Abstract: Disclosed are a door body for a refrigerator and a refrigerator with the same. The refrigerator includes a cabinet defining a storage compartment with a compartment opening, and the door body includes an inner door, an outer door and a storage box. The inner door is arranged at a position corresponding to the compartment opening on an outer side of the storage compartment, and is used to open and close the compartment opening. The outer door is arranged at a side of the inner door away from the storage compartment. The storage box is fixed to a side of the inner door close to the storage compartment; one end of the storage box close to the outer door has a storage opening, and an area of the inner door corresponding to the storage opening is provided with an inner door opening. The door body reduces the loss of cooling energy.

Abstract: The application provides a virtual object image display method and apparatus, an electronic device and a storage medium, relates to the field of artificial intelligence, in particular to the field of computer vision and deep learning, and may be applied to virtual object dialogue scenarios. The specific implementation scheme includes: segmenting acquired voice to obtain voice segments; predicting lip shape sequence information for the voice segments; searching for a corresponding lip shape image sequence based on the lip shape sequence information; performing lip fusion between the lip shape image sequence and a virtual object baseplate to obtain a virtual object image; displaying the virtual object image. The application improves ability to obtain virtual object image.

Abstract: The present application discloses a method and apparatus for determining the shape of the lips of a virtual character, a device and a computer storage medium, and relates to an artificial intelligence technology, and particularly to computer vision and deep learning technologies. An implementation includes: determining a phoneme sequence corresponding to a voice, the phoneme sequence including a phoneme corresponding to each time point; determining lip-shape key point information corresponding to each phoneme in the phoneme sequence; searching a pre-established lip shape library according to each piece of determined lip-shape key point information, so as to obtain a lip shape image of each phoneme; and corresponding the searched lip shape image of each phoneme with each time point to obtain a lip-shape image sequence corresponding to the voice. With the present application, the voice may be synchronized with the shapes of the lips in the images.

Abstract: A method and apparatus for processing character image data are provided. A specific embodiment of the method can include: acquiring a video including character images of a first character as first data, and acquiring a video including character images of a second character as second data, the video including character images of the first character including a plurality of types of movement-state images; replacing a head image extracted from the first data with a head image extracted from the second data; replacing a face extracted from the first data with a face extracted from the second data; and replacing the face in the replaced head image with the replaced face to obtain a target head image.

Abstract: A method for synthesizing a figure of a virtual object includes: obtaining a figure image of the virtual object, and original face images corresponding to a speech segment; extracting a first face key point of the face of the virtual object, and a second face key point of each of the original face images; processing the first face key point to generate a position and posture information of a first three-dimensional 3D face; processing each second face key point to generate vertex information of a second 3D face; generating a target face image corresponding to each original face image based on the position and the posture information of the first 3D face and the vertex information of each second 3D face; and synthesizing a speaking figure segment of the virtual object, corresponding to the speech segment, based on the figure image of the virtual object and each target face image.

Abstract: An image adjustment method and apparatus, an electronic device and a storage medium are provided. The image adjustment method includes: generating a combination image of a target person and a target clothing based on a target clothing image and a target person image; obtaining an adjustment parameter of the target clothing in the target clothing image based on image features of the target clothing image and image features of the combination image; obtaining a deformation image of the target clothing according to the adjustment parameter and the target clothing image.

Abstract: This application discloses a method and a device for dialogue with a virtual object, a client end and a storage medium. A specific implementation scheme of the method applied to the client end includes: converting a first voice collected by the client end into a first text content, in a case that the client end is in an offline mode; acquiring a second text content responding to the first text content based on offline natural language processing (NLP) and/or a target database pre-stored by the client end; performing voice synthesis on the second text content to acquire a second voice; simulating a lip shape of the second voice by using the virtual object to acquire a target video in which the virtual object says the second voice; and playing the target video.

Abstract: The application provides a virtual object image display method and apparatus, an electronic device and a storage medium, relates to the field of artificial intelligence, in particular to the field of computer vision and deep learning, and may be applied to virtual object dialogue scenarios. The specific implementation scheme includes: segmenting acquired voice to obtain voice segments; predicting lip shape sequence information for the voice segments; searching for a corresponding lip shape image sequence based on the lip shape sequence information; performing lip fusion between the lip shape image sequence and a virtual object baseplate to obtain a virtual object image; displaying the virtual object image. The application improves ability to obtain virtual object image.

Abstract: Sub-100 micron multimodal nanoparticles have four main components: 1) a target element (peptides, lipids, antibodies, small molecules, etc.) that can selectively bind to cells, tissues, or organs of the body; 2) a diagnostic agent such as a fluorophore or NMR contrast agent that allows visualization of nanoparticles at the site of delivery and/or a therapeutic or prophylactic agent; 3) an outside “stealth” layer that allows the particles to evade recognition by immune system components and increase particle circulation half-life; and 4) a biodegradable polymeric material, forming an inner core which can carry therapeutics and release the payloads at a sustained rate after systemic, intraperitoneal, or mucosal administration. These particles possess excellent stability, high loading efficiency, multiple agent encapsulation, targeting and imaging. They are targeted to sites of, or associated with, inflammation caused by a disease, disorder; trauma, chemotherapy or radiation.