Patents by Inventor Mingming Zhao

Mingming Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240418725
    Abstract: The present invention relates to a method for detecting and isolating a cell population co-expressing CD45 and EpCAM and the use thereof. In the present invention, a composition or a kit comprising an anti-CD45 antibody and an anti-EpCAM antibody is used for detecting and isolating a cell population co-expressing CD45 and EpCAM from PBMCs, and is used for rapid in-vitro screening of cancer, guiding treatment of cancer, and evaluating the effectiveness of cancer treatment.
    Type: Application
    Filed: August 23, 2024
    Publication date: December 19, 2024
    Applicant: Qingdao Sino-Cell Biomedicine Co., Ltd.
    Inventors: Zhen Sun, Bin Li, Wenjing Li, Mingming Zhao, Zeyao Wang, Wenna Liu, Qing Gao
  • Publication number: 20240393053
    Abstract: A heat dissipation assembly and a heat dissipator are disclosed. The heat dissipation assembly may include: a base plate bottom; a base plate cover connected to the base plate bottom and forming a heat collection cavity for concentrating heat; a turbulation component provided in the heat collection cavity, the turbulation component comprising at least one turbulation piece; and a plurality of heat dissipation components connected to the base plate cover, wherein the heat dissipation components are provided with at least one heat dissipation pipeline, the heat dissipation pipeline is provided in communication with the heat collection cavity.
    Type: Application
    Filed: March 14, 2022
    Publication date: November 28, 2024
    Inventors: Kaiwen DUAN, Shuai LI, Xin LIU, Fan LIU, Zhidong NIE, Yan WANG, Mingming ZHAO
  • Patent number: 11959103
    Abstract: Provided is a method for inducing pluripotent stem cells to differentiate into somatic cells in a culture medium containing a heparin binding growth factor, the method comprising bringing cells into contact with a conjugate of a laminin E8 fragment and a growth factor binding domain-containing fragment of a heparan sulfate proteoglycan. According to the present invention, pluripotent stem cells can be induced to differentiate into any desired somatic cells in a highly efficient manner.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: April 16, 2024
    Assignees: OSAKA UNIVERSITY, KYOTO UNIVERSITY
    Inventors: Kiyotoshi Sekiguchi, Fumi Ebisu, Hidetoshi Sakurai, Mingming Zhao, Megumu Saito
  • Publication number: 20230256024
    Abstract: The present invention provides a composition that is for treating myogenic diseases and that contains a cell group including skeletal muscle precursor cells differentiation-induced from pluripotent stem cells, the composition being characterized in that the cell group includes the skeletal muscle precursor cells that are Pax7-positive, and are CD146 (MCAM)-positive and CD57-negative on the surface thereof. The present invention also provides a method for purifying skeletal muscle precursor cells.
    Type: Application
    Filed: July 13, 2021
    Publication date: August 17, 2023
    Applicants: KYOTO UNIVERSITY, ASAHI KASEI KABUSHIKI KAISHA
    Inventors: Hidetoshi SAKURAI, Mingming ZHAO, Hiroki KATO, Atsutoshi TAZUMI
  • Publication number: 20230113511
    Abstract: Use of a N,N,N-trimethyl-5-aminopentanoic acid antagonist in the preparation of a medicament for treating fatty liver or heart failure and a system for diagnosing fatty liver or heart failure. New treatment regimens are provided for fatty liver or heart failure. By antagonizing TMAVA, the levels of triglyceride and free fatty acids in the plasma and liver of a patient can be reduced, and at the same time, the inhibition effect of TMAVA on the activity of ?-isopropylbetaine hydroxylase can also be eliminated, and the weakening of free fatty acid mitochondrial ?-oxidation caused by the decrease of endogenous carnitine synthesis is avoided. It is thus determined that reducing the ectopic accumulation of fatty acids in the liver and heart is clearly effective in treating fatty liver or heart failure.
    Type: Application
    Filed: February 26, 2021
    Publication date: April 13, 2023
    Inventors: Lemin ZHENG, Daowen WANG, Xiangbao MENG, Mingming ZHAO, Chenze LI
  • Patent number: 11288653
    Abstract: A method, apparatus and system for processing a payment request for a virtual commodity on an open network platform are provided. The method includes: receiving a payment request that is sent by a third-party application server according to a request from a terminal, the payment request carrying at least an account identifier; deducting a charge from an account corresponding to the account identifier according to a payment attribute corresponding to the account identifier; and sending a charge deduction result corresponding to the account to the terminal via the third-party application server. According to the present method, usage rate of network and system resources is improved.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: March 29, 2022
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Ding Zhang, Ningguo Chen, Jianwei Deng, Mingming Zhao, Hailiang Fan, Yulan Liao, Ruting Chen, Qiang Fei, Songjian Wang
  • Publication number: 20210012309
    Abstract: A method, apparatus and system for processing a payment request for a virtual commodity on an open network platform are provided. The method includes: receiving a payment request that is sent by a third-party application server according to a request from a terminal, the payment request carrying at least an account identifier; deducting a charge from an account corresponding to the account identifier according to a payment attribute corresponding to the account identifier; and sending a charge deduction result corresponding to the account to the terminal via the third-party application server. According to the present method, usage rate of network and system resources is improved.
    Type: Application
    Filed: September 24, 2020
    Publication date: January 14, 2021
    Inventors: Ding ZHANG, Ningguo CHEN, Jianwei DENG, Mingming ZHAO, Hailiang FAN, Yulan LIAO, Ruting CHEN, Qiang FEI, Songjian WANG
  • Patent number: 10839364
    Abstract: A method, apparatus and system for processing a payment request for a virtual commodity on an open network platform are provided. The method includes: receiving a payment request that is sent by a third-party application server according to a request from a terminal, the payment request carrying at least an account identifier; deducting a charge from an account corresponding to the account identifier according to a payment attribute corresponding to the account identifier; and sending a charge deduction result corresponding to the account to the terminal via the third-party application server. According to the present method, usage rate of network and system resources is improved.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: November 17, 2020
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Ding Zhang, Ningguo Chen, Jianwei Deng, Mingming Zhao, Hailiang Fan, Yulan Liao, Ruting Chen, Qiang Fei, Songjian Wang
  • Publication number: 20190287091
    Abstract: A method, apparatus and system for processing a payment request for a virtual commodity on an open network platform are provided. The method includes: receiving a payment request that is sent by a third-party application server according to a request from a terminal, the payment request carrying at least an account identifier; deducting a charge from an account corresponding to the account identifier according to a payment attribute corresponding to the account identifier; and sending a charge deduction result corresponding to the account to the terminal via the third-party application server. According to the present method, usage rate of network and system resources is improved.
    Type: Application
    Filed: May 31, 2019
    Publication date: September 19, 2019
    Inventors: Ding ZHANG, Ningguo CHEN, Jianwei DENG, Mingming ZHAO, Hailiang FAN, Yulan LIAO, Ruting CHEN, Qiang FEI, Songjian WANG
  • Publication number: 20190276804
    Abstract: Provided is a method for inducing pluripotent stem cells to differentiate into somatic cells in a culture medium containing a heparin binding growth factor, the method comprising bringing cells into contact with a conjugate of a laminin E8 fragment and a growth factor binding domain-containing fragment of a heparan sulfate proteoglycan. According to the present invention, pluripotent stem cells can be induced to differentiate into any desired somatic cells in a highly efficient manner.
    Type: Application
    Filed: November 9, 2017
    Publication date: September 12, 2019
    Applicants: OSAKA UNIVERSITY, KYOTO UNIVERSITY
    Inventors: Kiyotoshi SEKIGUCHI, Fumi EBISU, Hidetoshi SAKURAI, Mingming ZHAO, Megumu SAITO
  • Patent number: 10354244
    Abstract: A method, apparatus and system for processing a payment request for a virtual commodity on an open network platform are provided. The method includes: receiving a payment request that is sent by a third-party application server according to a request from a terminal, the payment request carrying at least an account identifier; deducting a charge from an account corresponding to the account identifier according to a payment attribute corresponding to the account identifier; and sending a charge deduction result corresponding to the account to the terminal via the third-party application server. According to the present method, usage rate of network and system resources is improved.
    Type: Grant
    Filed: July 23, 2015
    Date of Patent: July 16, 2019
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Ding Zhang, Ningguo Chen, Jianwei Deng, Mingming Zhao, Hailiang Fan, Yulan Liao, Ruting Chen, Qiang Fei, Songjian Wang
  • Patent number: 10149922
    Abstract: Disclosed is a patch system for use in a patient with a damaged heart. The patch comprises both a biodegradable engineered collagen scaffold to provide structural support to the injured heart and therapeutic agents, which are delivered by the patch to the heart. The scaffold consists of a dense collagen lamella produced by plastic compression with biomechanical properties that make it compatible with beating heart tissue, e.g. stiffness in a predefined range. One therapeutic agent, Fstl1, is shown to induce cardiomyocyte proliferation and enhance cardiac regeneration after injury. The patch can also be loaded with functionalized nanoparticles to yield multi-modal imaging capabilities in vivo. Also disclosed is a method for implanting the patch onto a patient's heart.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: December 11, 2018
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Pilar Ruiz-Lozano, Vahid Serpooshan, Mingming Zhao, Daniel Bernstein, Mark Mercola, Ke Wei
  • Patent number: 10135939
    Abstract: A method and apparatus for sending a delivery notification of a network application-related product are provided. The method includes: selecting a delivery executing server in advance from multiple delivery servers of an application; acquiring quality of service information of the delivery executing server of the application; judging, according to a predefined judging rule, whether the quality of service information meets a requirement; and if the requirement is met, retaining the delivery executing server unchanged; otherwise, setting another delivery server of the application as a delivery executing server; and sending a delivery notification to a current delivery executing server of the application upon detecting the delivery notification of the application to be sent.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: November 20, 2018
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Mingming Zhao, Ningguo Chen, Jianwei Deng, Ding Zhang, Chaofan Zhou, Qiang Fei, Songjian Wang, Peng Ye
  • Patent number: 9914711
    Abstract: The invention relates to a compound of formula I, and a preparation method and use thereof. The compound has a bacterial quorum-sensing regulatory effect, and can be used for prevention and/or treatment of a disease caused by a bacterial infection.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: March 13, 2018
    Assignee: Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
    Inventors: Song Li, Junhai Xiao, Mingming Zhao, Wu Zhong, Lili Wang, Zhibing Zheng, Yunde Xie, Xingzhou Li, Guoming Zhao, Xinbo Zhou, Xiaokui Wang, Wei Chen
  • Patent number: 9630939
    Abstract: A derivative of homoserine lactone represented by formula I, and a preparation method and use thereof. The compound has a bacterial quorum-sensing regulatory effect, and can be used for prevention and/or treatment of a disease caused by a bacterial infection.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: April 25, 2017
    Assignee: INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA
    Inventors: Song Li, Junhai Xiao, Mingming Zhao, Wu Zhong, Lili Wang, Zhibing Zheng, Yunde Xie, Xingzhou Li, Guoming Zhao, Xinbo Zhou, Xiaokui Wang, Wei Chen
  • Patent number: D780682
    Type: Grant
    Filed: May 4, 2015
    Date of Patent: March 7, 2017
    Inventors: Mingming Zhao, Wen Sun, Yixin Zhang, Junjie Liu, Junrui Wan, Xiaoyun Li, Na Bai
  • Patent number: D807810
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: January 16, 2018
    Inventors: Hongling Zhao, Mingming Zhao, Xueyi Wang, Wen Sun
  • Patent number: D862375
    Type: Grant
    Filed: January 13, 2018
    Date of Patent: October 8, 2019
    Assignee: Qingdao Sentury Tire Co., Ltd.
    Inventors: Mingming Zhao, Hairong Fu, Wen Sun
  • Patent number: D864848
    Type: Grant
    Filed: January 13, 2018
    Date of Patent: October 29, 2019
    Assignee: Qingdao Sentury Tire Co., Ltd.
    Inventors: Yixin Zhang, Xueyi Wang, Mingming Zhao, Wen Sun
  • Patent number: D887344
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: June 16, 2020
    Inventors: Jingjing Ma, Mingming Zhao, Xueyi Wang, Wen Sun