Patents by Inventor Mingqiang Zhang
Mingqiang Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240129197Abstract: A method for constructing a multistage network includes: deploying a plurality of nodes; constructing the upper network with at least one node of the plurality of nodes; and in response to determining there is an isolated node, determining an intermediate node for the isolated node and adding the isolated node into the upper network or one of the at least one sub-network according to the intermediate node.Type: ApplicationFiled: October 12, 2023Publication date: April 18, 2024Applicant: Beijing Jiaotong UniversityInventors: Xu LI, Mingqiang YANG, Yanan LIANG, Fukang ZHAO, Yunfei ZHANG, Zhihao ZHOU, Jun XIE, Zike WEI
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Publication number: 20240090127Abstract: Provided is a flexible circuit board. The flexible circuit board includes a circuit substrate; wherein the circuit substrate is a multilayer flexible circuit board, wherein at least two layers of the multilayer flexible circuit board include plated sublayers, and a plurality of grooves are disposed in a first surface of the multilayer flexible circuit board, a depth of the groove being not less than a depth of the plated sublayer closest to the first surface in the multilayer flexible circuit board.Type: ApplicationFiled: October 22, 2021Publication date: March 14, 2024Inventors: Yonglin CHEN, Yunhan XIAO, Hongjin HU, Jiaxiang ZHANG, Kun ZUO, Mingqiang WANG, Jiuyuan BAI
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Publication number: 20180325110Abstract: A micro-carbon plant anthocyanin for facilitating advancement of fruit coloring and fruit plumpness, and a preparation method and application thereof are provided. The formula composition of the micro-carbon plant anthocyanin by mass percentage is 30-50% of plant anthocyanin having a particle size of 80-150 ?m, 20-40% of micro carbon (abbreviation for water-soluble small-molecule carbohydrates) having a particle size of 100 ?m and 20-50% of amino acids. By spraying a 100-500-fold dilution of the micro-carbon plant anthocyanin onto surfaces of foliage and fruits during the fruit development period of grapes and strawberries with a use amount of 10-50 kg/mu in the whole growth period, the colorization can be advanced by 5-15 days, and the harvested fruits have fragrant and sweet tastes, are completely filled, and have an excellent quality.Type: ApplicationFiled: June 17, 2016Publication date: November 15, 2018Inventor: Mingqiang Zhang
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Publication number: 20180319714Abstract: A micro-carbon bio-fertilizer for rapidly increasing a soil granular structure and a preparation method thereof are provided. The formula composition of the micro-carbon bio-fertilizer by mass percentage is: 30-60% of micro carbons, and 40-70% of plant fibers. The preparation process includes is that: preparation of raw materials; filtration and purification of the raw materials; biodegradation; canning of semi-finished product; dispensing and mixing; sedimentation and achievement of finished product. The macromolecular carbohydrates contained in the industrial wastewater rich in organic matters are activated into micro carbons of 100 ?m in average through biotechnologies. The micro carbons have natural affinity with soil and split the soil into small particles which are gathered to form a granular structure. Such a granular structure mitigates the degree of soil hardening and acidification, while quickly increasing soil fertility and improving crop quality and yield.Type: ApplicationFiled: June 17, 2016Publication date: November 8, 2018Inventor: Mingqiang Zhang
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Publication number: 20140213731Abstract: A supercritical carbon dioxide-assisted solid-phase grafting modification method for polypropylene, comprises swelling polypropylene for 0.5 to 10 hours in supercritical carbon dioxide having dissolved vinyl monomer and an initiator, then slowly relieving the pressure; moving the polypropylene that has undergone the swelling process into a reaction kettle, and adding xylene as an interface agent, the mass of xylene being 1% of the polypropylene; increasing the temperature to between 65° C. and 165° C. under normal pressure, and reacting 1 to 10 hours to obtain modified polypropylene; the swelling permeation temperature during the swelling process is from 31° C. to 60° C., the swelling pressure is from 7.5 to 12 MPa; the initiator is an azo compound or a peroxide. In the present method, the grafting rate reaches 5.4%, the thermal property, polarity, and mechanical property all improve substantially, and hydrophilic property is substantially enhanced.Type: ApplicationFiled: April 13, 2012Publication date: July 31, 2014Applicant: Petrochina Company LimitedInventors: Wenyan Wang, Mingqiang Zhang, Jian Wang, Dengfei Wang, Enguang Zou, Liping Qiu, Qun Dong, Jinxian Jiang, Jianying Ma, Tengjie Ge, Yanjie An, Deying Zhang, Bo Li, Gujyue Guo, Shihua Wang, He Ren, Lirong Jing, Haifeng Guo
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Patent number: 8034804Abstract: The present invention relates to (pyrido/thieno)-[f]-oxazepine-5-one derivatives having the general Formula I wherein R1, R2 and R3 are independently H or (C1-4)alkyl; Ar represents a fused thiophene or pyridine ring optionally substituted with one or more substituents selected from (C1-4)alkyl, (C1-4)alkyloxy, (C1-4)alkyloxy(C1-4)alkyl, CF3, halogen, nitro, cyano, NR4R5, NR4COR6, and CONR4R5; R4 and R5 are independently H or (C1-4)-alkyl; or R4 and R5 form together with the nitrogen atom to which they are bound a 5- or 6-membered saturated heterocyclic ring, optionally containing a further heteroatom selected from O, S or NR6; R6 is (C1-4)alkyl; A represents the residue of a 4-7 membered saturated heterocyclic ring, optionally containing an oxygen atom, the ring being optionally substituted with 1-3 substituents selected from (C1-4)alkyl, (C1-4)-alkyloxy, hydroxy, halogen and oxo; or a pharmaceutically acceptable salt thereof.Type: GrantFiled: February 20, 2009Date of Patent: October 11, 2011Assignee: N.V. OrganonInventors: Simon James Anthony Grove, Julia Adam-Worrall, Mingqiang Zhang, Robert Gilfillan
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Patent number: 8008318Abstract: The present invention relates to 39-desmethoxyrapamycin derivatives and their uses thereof. The present invention provides for the use of these compounds in the treatment of cancer and/or B-cell malignancies, the induction or maintenance of immunosuppression, the treatment of transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation, vascular disease and fibrotic diseases, the stimulation of neuronal regeneration or the treatment of fungal infections.Type: GrantFiled: December 3, 2009Date of Patent: August 30, 2011Assignee: Biotica Technology LimitedInventors: Christoph Hendrik Beckmann, Steven James Moss, Rose Mary Sheridan, Mingqiang Zhang, Barrie Wilkinson
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Patent number: 7897608Abstract: The present invention relates to novel 39-desmethoxy-39-methylrapamycin derivatives, methods for their production, and uses thereof. In a further aspect the present invention provides for the use of these 39-desmethoxy-39 -methylrapamycin derivatives in the treatment of cancer and/or B-cell malignancies, the induction or maintenance of immunosuppression, the treatment of transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation, vascular disease and fibrotic diseases, the stimulation of neuronal regeneration or the treatment of fungal infections.Type: GrantFiled: November 19, 2008Date of Patent: March 1, 2011Assignee: Biotica Technology LimitedInventors: Barrie Wilkinson, Mingqiang Zhang, Rose Mary Sheridan
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Publication number: 20100081682Abstract: The present invention relates to 39-desmethoxyrapamycin derivatives and their uses thereof. The present invention provides for the use of these compounds in the treatment of cancer and/or B-cell malignancies, the induction or maintenance of immunosuppression, the treatment of transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation, vascular disease and fibrotic diseases, the stimulation of neuronal regeneration or the treatment of fungal infections.Type: ApplicationFiled: December 3, 2009Publication date: April 1, 2010Applicant: Biotica Technology LimitedInventors: Christoph Hendrik Beckmann, Steven James Moss, Rose Mary Sheridan, Mingqiang Zhang, Barrie Wilkinson
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Publication number: 20100061994Abstract: The present invention relates to medical uses of 39-desmethoxyrapamycin analogues.Type: ApplicationFiled: March 10, 2006Publication date: March 11, 2010Inventors: Rose Mary Sheridan, Mingqiang Zhang, Matthew Alan Gregory
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Patent number: 7655673Abstract: The present invention relates to medical uses of 39-desmethoxyrapamycin.Type: GrantFiled: January 10, 2007Date of Patent: February 2, 2010Assignee: Biotica Technology LimitedInventors: Mingqiang Zhang, Rose Mary Sheridan
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Patent number: 7648996Abstract: The present invention relates to novel 39-desmethoxyrapamycin derivatives, methods for their production, and uses thereof. In a further aspect the present invention provides for the use of these 39-desmethoxyrapamycin derivatives in the treatment of cancer and/or B-cell malignancies, the induction or maintenance of immunosuppression, the treatment of transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation, vascular disease and fibrotic diseases, the stimulation of neuronal regeneration or the treatment of fungal infections.Type: GrantFiled: March 10, 2006Date of Patent: January 19, 2010Assignee: Biotica Technology LimitedInventors: Christoph Hendrik Beckmann, Steven James Moss, Rose Mary Sheridan, Mingqiang Zhang, Barrie Wilkinson
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Patent number: 7566778Abstract: The present invention relates to (pyrido/thieno)-[f]-oxazepine-5-one derivatives having the general Formula I wherein R1, R2 and R3 are independently H or (C1-4)alkyl; Ar represents a fused thiophene or pyridine ring optionally substituted with one or more substituents selected from (C1-4)alkyl, (C1-4)alkyloxy, (C1-4)alkyloxy(C1-4)alkyl, CF3, halogen, nitro, cyano, NR4R5, NR4COR6, and CONR4R5; R4 and R5 are independently H or (C1-4-)alkyl; or R4 and R5 form together with the nitrogen atom to which they are bound a 5- or 6-membered saturated heterocyclic ring, optionally containing a further heteroatom selected from O, S or NR6; R6 is (C1-4)alkyl; A represents the residue of a 4-7 membered saturated heterocyclic ring, optionally containing an oxygen atom, the ring being optionally substituted with 1-3 substituents selected from (C1-4)alkyl, (C1-4)alkyloxy, hydroxy, halogen and oxo; or a pharmaceutically acceptable salt thereof.Type: GrantFiled: February 1, 2008Date of Patent: July 28, 2009Assignee: N.V. OrganonInventors: Simon James Anthony Grove, Julia Adam-Worrall, Mingqiang Zhang, Robert Gilfillan
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Publication number: 20090163473Abstract: The present invention relates to (pyrido/thieno)-[f]-oxazepine-5-one derivatives having the general Formula I wherein R1, R2 and R3 are independently H or (C1-4)alkyl; Ar represents a fused thiophene or pyridine ring optionally substituted with one or more substituents selected from (C1-4)alkyl, (C1-4)alkyloxy, (C1-4)alkyloxy(C1-4)alkyl, CF3, halogen, nitro, cyano, NR4R5, NR4COR6, and CONR4R5; R4 and R5 are independently H or (C1-4)-alkyl; or R4 and R5 form together with the nitrogen atom to which they are bound a 5- or 6-membered saturated heterocyclic ring, optionally containing a further heteroatom selected from O, S or NR6; R6 is (C1-4)alkyl; A represents the residue of a 4-7 membered saturated heterocyclic ring, optionally containing an oxygen atom, the ring being optionally substituted with 1-3 substituents selected from (C1-4)alkyl, (C1-4)-alkyloxy, hydroxy, halogen and oxo; or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: February 20, 2009Publication date: June 25, 2009Inventors: Simon James Anthony Grove, Julia Adam-Worrall, Mingqiang Zhang, Robert Gilfillan
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Patent number: 7504390Abstract: The present invention relates to benzoxazepine derivative having the general formula I, wherein X represents CO or SO2; R1, R2, R3 and R4 are independently selected from H, (C1-4)alkyl, (C1-4)alkyloxy, (C1-4)alkyloxy(C1-4)alkyl, halogen, nitro, cyano, NR8R9, NR8COR10, and CONR8R9, R5, R6 and R7 are independently H or (C1-4)alkyl; R8 and R9 are independently H or (C1-4)alkyl; or R8 and R9 form together with the nitrogen atom to which they are bound a 5- or 6-membered saturated heterocyclic ring, optionally containing a further heteroatom selected from O, S or NR11; R10 is (C1-4)alkyl; R11 is (C1-4)alkyl; A represents the residue of a 4-7 membered saturated heterocyclic ring, optionally containing an oxygen atom, the ring being optionally substituted with 1-3 substituents selected from (C1-4)alkyl, (C1-4)alkyloxy, hydroxy, halogen and oxo; or a pharmaceutically acceptable salt thereof.Type: GrantFiled: October 25, 2007Date of Patent: March 17, 2009Assignee: N.V. OrganonInventors: Simon James Anthony Grove, Mingqiang Zhang, Mohammad Shahid
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Publication number: 20080262221Abstract: The present invention relates to (pyrido/thieno)-[f]-oxazepine-5-one derivatives having the general Formula I wherein R1, R2 and R3 are independently H or (C1-4)alkyl; Ar represents a fused thiophene or pyridine ring optionally substituted with one or more substituents selected from (C1-4)alkyl, (C1-4)alkyloxy, (C1-4)alkyloxy(C1-4)alkyl, CF3, halogen, nitro, cyano, NR4R5, NR4COR6, and CONR4R5; R4 and R5 are independently H or (C1-4-)alkyl; or R4 and R5 form together with the nitrogen atom to which they are bound a 5- or 6-membered saturated heterocyclic ring, optionally containing a further heteroatom selected from O, S or NR6; R6 is (C1-4)alkyl; A represents the residue of a 4-7 membered saturated heterocyclic ring, optionally containing an oxygen atom, the ring being optionally substituted with 1-3 substituents selected from (C1-4)alkyl, (C1-4)alkyloxy, hydroxy, halogen and oxo; or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: February 1, 2008Publication date: October 23, 2008Applicant: N.V. OrganonInventors: Simon James Anthony Grove, Julia Adam-Worall, Mingqiang Zhang, Robert Gilfillan
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Publication number: 20080188511Abstract: The present invention relates to novel 39-desmethoxyrapamycin derivatives, methods for their production, and uses thereof. In a further aspect the present invention provides for the use of these 39-desmethoxyrapamycin derivatives in the treatment of cancer and/or B-cell malignancies, the induction or maintenance of immunosuppression, the treatment of transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation, vascular disease and fibrotic diseases, the stimulation of neuronal regeneration or the treatment of fungal infections.Type: ApplicationFiled: March 10, 2006Publication date: August 7, 2008Inventors: Christoph Hendrik Beckmann, Steven James Moss, Rose Mary Sheridan, Mingqiang Zhang, Barrie Wilkinson
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Publication number: 20080139529Abstract: The present invention relates to benzoxazepine derivative having the general formula I, wherein X represents CO or S02; R1, R2, R3 and R4 are independently selected from H, (C1-4)alkyl, (C1-4)alkyloxy, (C1-4)alkyloxy(C1-4)alkyl, halogen, nitro, cyano, NR8R9, NR8COR10, and CONR8R9, R5, R6 and R7 are independently H or (C1-4)alkyl; R8 and R9 are independently H or (C1-4)alkyl; or R8 and R9 form together with the nitrogen atom to which they are bound a 5- or 6-membered saturated heterocyclic ring, optionally containing a further heteroatom selected from O, S or NR11; R10 is (C1-4)alkyl; R11 is (C1-4)alkyl; A represents the residue of a 4-7 membered saturated heterocyclic ring, optionally containing an oxygen atom, the ring being optionally substituted with 1-3 substituents selected from (C1-4)alkyl, (C1-4)alkyloxy, hydroxy, halogen and oxo; or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: October 25, 2007Publication date: June 12, 2008Applicant: N.V. OrganonInventors: Simon James Anthony Grove, Mingqiang Zhang, Mohammad Shahid
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Patent number: 7307073Abstract: The present invention relates to benzoxazepine derivative having the general formula I, wherein X represents CO or SO2; R1, R2, R3 and R4 are independently selected from H, (C1-4)alkyl, (C1-4)alkyloxy, (C1-4)alkyloxy(C1-4)alkyl, halogen, nitro, cyano, NR8R9, NR8COR10, and CONR8R9, R5, R6 and R7 are independently H or (C1-4)alkyl; R8 and R9 are independently H or (C1-4)alkyl; or R8 and R9 form together with the nitrogen atom to which they are bound a 5- or 6-membered saturated heterocyclic ring, optionally containing a further heteroatom selected from O, S or NR11; R10 is (C1-4)alkyl; R11 is (C1-4)alkyl; A represents the residue of a 4-7 membered saturated heterocyclic ring, optionally containing an oxygen atom, the ring being optionally substituted with 1-3 substituents selected from (C1-4)alkyl, (C1-4)alkyloxy, hydroxy, halogen and oxo; or a pharmaceutically acceptable salt thereof.Type: GrantFiled: June 5, 2002Date of Patent: December 11, 2007Assignee: N.V. OrganonInventors: Simon James Anthony Grove, Mingqiang Zhang, Mohammad Shahid
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Publication number: 20070184075Abstract: The present invention relates to medical uses of 39-desmethoxyrapamycin.Type: ApplicationFiled: January 10, 2007Publication date: August 9, 2007Inventors: Mingqiang Zhang, Rose Mary Sheridan