Abstract: A myocardial multi-parametric ultrasound imaging method includes: emitting alternately a plurality of ascending and descending large-acoustic domain diverging waves to myocardial tissue to obtain raw channel data; performing beamforming to obtain a plurality of radio frequency data; performing myocardial edge detection and identification according to the radio frequency data to generate myocardial mask; and estimating a large-displacement estimation term, a small-displacement estimation term, and a regularization term to construct a myocardial displacement estimation cost function; and obtaining the myocardial displacement parameters according to the cost function; and performing strain estimation. A myocardial multi-parametric ultrasound imaging system is further provided.

Abstract: A recognition, monitoring, and imaging method and system are provided for a thermal ablation region based on ultrasonic deep learning. The recognition method includes obtaining original ultrasonic radiofrequency data, an ultrasonic image, and an optical image during thermal ablation; making ultrasonic radiofrequency data points and pixels in the optical image correspond in a one-to-one manner, and determining a spatial position correspondence between the ultrasonic radiofrequency data points and the optical image; determining a thermal ablation region image according to the spatial position correspondence; constructing a deep learning model according to the thermal ablation region image; superposing a thermal ablation classification image to the ultrasonic image, to determine a to-be-recognized thermal ablation image; and recognizing a thermal ablation region in the ultrasonic image according to the to-be-recognized thermal ablation image.

Abstract: A method for controlling a histotripsy using a confocal fundamental and harmonic superposition combined with hundred-microsecond ultrasound pulses, including: 1) positioning a target tissue by a monitoring and guiding system and adjusting a position of the target tissue to a focal point of a transducer; 2) first stage: controlling the confocal fundamental and harmonic superposition combined with hundred-microsecond ultrasound pulses to form a shock wave in a focal zone; wherein a negative acoustic pressure exceeds a cavitation threshold; an inertial cavitation occurs to generate boiling bubbles; the boiling bubbles collapse and achieve partial homogenization of the target tissue; 3) second stage: controlling the confocal fundamental and harmonic superposition combined with hundred-microsecond pulsed-ultrasound sequences to simultaneously irradiate a target zone and further mechanically disintegrate and homogenize the target tissue.

Abstract: A recognition, monitoring, and imaging method and system are provided for a thermal ablation region based on ultrasonic deep learning. The recognition method includes obtaining original ultrasonic radiofrequency data, an ultrasonic image, and an optical image during thermal ablation; making ultrasonic radiofrequency data points and pixels in the optical image correspond in a one-to-one manner, and determining a spatial position correspondence between the ultrasonic radiofrequency data points and the optical image; determining a thermal ablation region image according to the spatial position correspondence; constructing a deep learning model according to the thermal ablation region image; superposing a thermal ablation classification image to the ultrasonic image, to determine a to-be-recognized thermal ablation image; and recognizing a thermal ablation region in the ultrasonic image according to the to-be-recognized thermal ablation image.

Abstract: A spherical-confocal-split array with dual frequency of fundamental and harmonic superimposition includes: array elements which are spherically confocal, whose quantity is an even number, wherein a half of the array elements operate with a lower frequency, and the other half of the array elements operate with a higher frequency; both the lower frequency and the higher frequency are MHz high-frequencies; each of the array elements corresponds to a frequency drive; array element beams don't superimpose outside the focal region; each of the array elements is connected to a channel amplifier (3) through corresponding impedance matching (2); and a multi-channel waveform controller (4) is connected to the channel amplifier (3) for controlling amplitudes and phases of all channels. The dual-frequency spherical sectorial split array is able to generate split multi-foci of the focal plane with the dual frequencies; and control strong interference of transient cavitation clouds at the adjacent foci.

Abstract: A high-spatial-resolution ultrasonic neuromodulation method and system are provided. The method includes infusing a biological micro-nano material into the operating object by injection; aggregating the biological micro-nano material in the target region by a micro-nano manipulation method; and conducting ultrasonic neuromodulation on the target region by utilizing the ultrasound transducer and using an acoustic intensity between the first minimum acoustic intensity and the second minimum acoustic intensity. By using the method, an ultrasonic neuromodulation effect is generated only in a micro-nano material aggregation region by using a lower acoustic intensity, thereby reducing the threshold of ultrasonic neuromodulation, and greatly improving the spatial resolution of the ultrasonic neuromodulation.

Abstract: A method for controlling a histotripsy using a confocal fundamental and harmonic superposition combined with hundred-microsecond ultrasound pulses, including: 1) positioning a target tissue by a monitoring and guiding system and adjusting a position of the target tissue to a focal point of a transducer; 2) first stage: controlling the confocal fundamental and harmonic superposition combined with hundred-microsecond ultrasound pulses to form a shock wave in a focal zone; wherein a negative acoustic pressure exceeds a cavitation threshold; an inertial cavitation occurs to generate boiling bubbles; the boiling bubbles collapse and achieve partial homogenization of the target tissue; 3) second stage: controlling the confocal fundamental and harmonic superposition combined with hundred-microsecond pulsed-ultrasound sequences to simultaneously irradiate a target zone and further mechanically disintegrate and homogenize the target tissue.

Abstract: A three-dimensional cavitation quantitative imaging method for a microsecond-resolution cavitation spatial-temporal distribution includes steps of: after each wide beam detection, moving an array transducer by one unit; waiting until the cavitation nuclei distribution backs to an initial state, then detecting the cavitation by the wide beam detection with same cavitation energy incitation, so as to obtain a spatial series of two-dimensional cavitation raw radio frequency data corresponding to different placing positions of the array transducer; then changing the cavitation energy source duration, time delays between energy source incitation and the wide beam transmitted by the array transducer, and time delays between the pulsating pump and energy source incitation, so as to obtain a temporal series of two-dimensional cavitation raw radio frequency data; and then obtaining a microsecond-resolution three-dimensional cavitation spatial-temporal distribution image and a cavitation micro bubble concentration quan

Abstract: A contrast imaging method based on a wide beam and a method for extracting a perfusion time-intensity curve (TIC) are provided to increase contrast-to-tissue ratio (CTR) through the contrast imaging method based on the wide beam via a pulse inversion microbubble wavelet transform sum squared differences decorrelation (PIWSSD). An auto adaptive analysis method about rapidly and accurately extracting a TIC tendency of the contrast imaging method based on the wide beam is also provided to overcome limitations of a decrease in the CTR of the contrast imaging based on the wide beam and a decrease in SCR of the perfusion TIC. The present invention plays an important role in effectively reducing an ultrasound contrast imaging acoustic power and a contrast microbubble perfusion concentration, reducing potential threat to human body, acquiring a contrast image with the high CTR, and accurately evaluating and diagnosing blood perfusion.

Abstract: A spherical-confocal-split array with dual frequency of fundamental and harmonic superimposition includes: array elements which are spherically confocal, whose quantity is an even number, wherein a half of the array elements operate with a lower frequency, and the other half of the array elements operate with a higher frequency; both the lower frequency and the higher frequency are MHz high-frequencies; each of the array elements corresponds to a frequency drive; array element beams don't superimpose outside the focal region; each of the array elements is connected to a channel amplifier (3) through corresponding impedance matching (2); and a multi-channel waveform controller (4) is connected to the channel amplifier (3) for controlling amplitudes and phases of all channels. The dual-frequency spherical sectorial split array is able to generate split multi-foci of the focal plane with the dual frequencies; and control strong interference of transient cavitation clouds at the adjacent foci.

Abstract: A three-dimensional cavitation quantitative imaging method for a microsecond-resolution cavitation spatial-temporal distribution includes steps of: after each wide beam detection, moving an array transducer by one unit; waiting until the cavitation nuclei distribution backs to an initial state, then detecting the cavitation by the wide beam detection with same cavitation energy incitation, so as to obtain a spatial series of two-dimensional cavitation raw radio frequency data corresponding to different placing positions of the array transducer; then changing the cavitation energy source duration, time delays between energy source incitation and the wide beam transmitted by the array transducer, and time delays between the pulsating pump and energy source incitation, so as to obtain a temporal series of two-dimensional cavitation raw radio frequency data; and then obtaining a microsecond-resolution three-dimensional cavitation spatial-temporal distribution image and a cavitation micro bubble concentration quan

Abstract: An imaging and measuring system of vocal cord vibration based on plane wave ultrasonography, includes: a digital ultrasonography system, a data acquisition unit, and a computer; wherein the digital ultrasonography system comprises an ultrasound linear array transducer and a host; wherein the ultrasound linear array transducer is controlled by the host for sending an ultrasound plane wave and receiving echo; the echo is sent back to data acquisition unit; wherein the data acquisition unit converts the echo into digital signal and then sends it to the computer; wherein the computer provides beamforming, envelope detection, and dynamic range compression of the digital signal received, for obtaining a laryngeal tissue structure image. The present invention provides high-speed imaging of the vocal cord vibration with temproal and spatial synchronization, and quantitatively extracting information of biomechanical parameters as well as vibrational phase changes.

Abstract: A contrast imaging method based on a wide beam and a method for extracting a perfusion time-intensity curve (TIC) are provided to increase contrast-to-tissue ratio (CTR) through the contrast imaging method based on the wide beam via a pulse inversion microbubble wavelet transform sum squared differences decorrelation (PIWSSD). An auto adaptive analysis method about rapidly and accurately extracting a TIC tendency of the contrast imaging method based on the wide beam is also provided to overcome limitations of a decrease in the CTR of the contrast imaging based on the wide beam and a decrease in SCR of the perfusion TIC. The present invention plays an important role in effectively reducing an ultrasound contrast imaging acoustic power and a contrast microbubble perfusion concentration, reducing potential threat to human body, acquiring a contrast image with the high CTR, and accurately evaluating and diagnosing blood perfusion.

Abstract: The invention provides an electrolaryngeal speech reconstruction method and a system thereof. Firstly, model parameters are extracted from the collected speech as a parameter library, then facial images of a speaker are acquired and then transmitted to an image analyzing and processing module to obtain the voice onset and offset times and the vowel classes, then a waveform of a voice source is synthesized by a voice source synthesis module, finally, the waveform of the above voice source is output by an electrolarynx vibration output module, wherein the voice source synthesis module firstly sets the model parameters of a glottal voice source so as to synthesize the waveform of the glottal voice source, and then a waveguide model is used to simulate sound transmission in a vocal tract and select shape parameters of the vocal tract according to the vowel classes.

Abstract: The invention provides an electrolaryngeal speech reconstruction method and a system thereof. Firstly, model parameters are extracted from the collected speech as a parameter library, then facial images of a speaker are acquired and then transmitted to an image analyzing and processing module to obtain the voice onset and offset times and the vowel classes, then a waveform of a voice source is synthesized by a voice source synthesis module, finally, the waveform of the above voice source is output by an electrolarynx vibration output module, wherein the voice source synthesis module firstly sets the model parameters of a glottal voice source so as to synthesize the waveform of the glottal voice source, and then a waveguide model is used to simulate sound transmission in a vocal tract and select shape parameters of the vocal tract according to the vowel classes.