Abstract: Techniques for particle beam therapy include receiving a target region inside a subject for particle therapy, a minimum dose inside the target region, and a maximum dose inside the subject but outside target region. Multiple beam axis angles are determined, each involving a gantry angle and a couch position. Multiple spots within the target region are determined. For each beam axis angle a pristine particle scan beam (not coaxial with any other particle scan beam) is determined such that a Bragg Peak is directed to a spot, and repeated until every spot is subjected to a Bragg Peak or an intersection of two or more such pristine scan beams. Output data indicating the pristine beamlets is stored for operation of a particle beam therapy apparatus.

Abstract: Techniques for particle beam therapy include receiving a target region inside a subject for particle therapy, a minimum dose inside the target region, and a maximum dose inside the subject but outside target region. Multiple beam axis angles are determined, each involving a grantry angle and a couch position. Multiple spots within the target region are determined. For each beam axis angle a pristine particle scan beam (not coaxial with any other particle scan beam) is determined such that a Bragg Peak is directed to a spot, and repeated until every spot is subjected to a Bragg Peak or an intersection of two or more such pristine scan beams. Output data indicating the pristine beamlets is stored for operation of a particle beam therapy apparatus.

Abstract: A treatment planning system for generating patient-specific treatment. The system including one or more processors programmed to receive a radiation treatment plan (RTP) for irradiating a target over the course of one or more treatment fractions, said RTP including a planned dose distribution to be delivered to the target, receive motion data for at least one of the treatment fractions of the RTP, receive temporal delivery metric data for at least one of the treatment fractions of the RTP, calculate a motion-compensated dose distribution for the target using the motion data and the temporal delivery metric data to adjust the planned dose distribution based on the received motion data and temporal delivery metric data, and compare the motion-compensated dose distribution to the planned dose distribution.

Abstract: A treatment planning system for generating patient-specific treatment. The system including one or more processors programmed to receive a radiation treatment plan (RTP) for irradiating a target over the course of one or more treatment fractions, said RTP including a planned dose distribution to be delivered to the target, receive motion data for at least one of the treatment fractions of the RTP, receive temporal delivery metric data for at least one of the treatment fractions of the RTP, calculate a motion-compensated dose distribution for the target using the motion data and the temporal delivery metric data to adjust the planned dose distribution based on the received motion data and temporal delivery metric data, and compare the motion-compensated dose distribution to the planned dose distribution.

Abstract: Carbon nanoflakes, methods of making the nanoflakes, and applications of the carbon nanoflakes are provided. In some embodiments, the carbon nanoflakes are carbon nanosheets, which are less than 2 nm thick. The carbon nanoflakes may be made using RF-PECVD. Carbon nanoflakes may be useful as field emitters, for hydrogen storage applications, for sensors, and as catalyst supports.

Abstract: Carbon nanoflakes, methods of making the nanoflakes, and applications of the carbon nanoflakes are provided. In some embodiments, the carbon nanoflakes are carbon nanosheets, which are less than 2 nm thick. The carbon nanoflakes may be made using RF-PECVD. Carbon nanoflakes may be useful as field emitters, for hydrogen storage applications, for sensors, and as catalyst supports.

Abstract: Novel compositions and morphologies of carbon nanoflakes are described, as well as methods for making carbon nanoflakes using a radio frequency plasma enhanced chemical vapor deposition (RF-PECVD) process. Acetylene is used as a CVD source gas. By utilizing high concentrations of acetylene in the CVD source gas at relatively low temperatures, carbon nanoflake growth rate and robustness are improved, and the resulting carbon nanoflakes have enhanced height uniformity.