Patents by Inventor Mingyong Han
Mingyong Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120288949Abstract: The present invention relates to a method for determining the presence or amount of a compound in a sample by interparticle distance-dependent sensing, comprising: (a) contacting the sample suspected of containing the compound with rare earth doped metal oxide nanoparticles; and (b) detecting the compound by determining the change in luminescent properties of the rare earth doped metal oxide nanoparticles upon contact with the sample.Type: ApplicationFiled: March 14, 2012Publication date: November 15, 2012Inventors: Si Yin TEE, Enyi Ye, Yin Win Khin, Suo Hon Lim, Mingyong Han
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Publication number: 20120045514Abstract: The present invention relates to a microparticle and its use. The microparticle has a width of at least about 1 micron. The microparticle includes a biocompatible polymer, a nanoparticle, and an anti-cancer agent.Type: ApplicationFiled: November 24, 2009Publication date: February 23, 2012Applicant: Agency for Science, Technology and ResearchInventors: Yin Win Khin, Enyi Ye, Mingyong Han
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Publication number: 20120032122Abstract: The present invention provides a method of forming a nanocrystal of the composition CdA, with A being S or Se. The method includes forming in a suitable solvent a solution of cadmium, or a compound thereof, in a form suitable for the generation of a nanocrystal. The solvent includes a compound selected from an ether and an amine. The method further includes bringing the solution to a temperature selected in the range from about 20° C. to about 200° C. The method also includes adding at the temperature selected in the range from about 20° C. to about 200° C. the element A in a form suitable for the generation of a nanocrystal. Thereby the forming of a nanocrystal of the composition CdA is allowed.Type: ApplicationFiled: August 6, 2007Publication date: February 9, 2012Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Yun Zong, Mingyong Han, Wolfgang Knoll
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Publication number: 20110233468Abstract: Provided is a process of forming a Cd and Se containing nanocrystalline composite. The nanocrystalline composite has a composition of one of (a) Cd, M, Se, (b) Cd, Se, A, and (c) Cd, M, Se, A, with M being an element of group (12) of the PSE other than Cd and A being an element of group (16) of the PSE other than O and Se. In one embodiment in a suitable solvent a solution of the element Cd, or a precursor thereof, and, where applicable, of M, or a precursor thereof is formed. To the solution the element Se and, where applicable, A is added and thereby a reaction mixture formed. The reaction mixture is heated for a sufficient period of time at a temperature suitable for forming the Cd and Se containing nanocrystalline composite and then the reaction mixture is allowed to cool. Finally the Cd and Se containing nanocrystalline composite isolated.Type: ApplicationFiled: August 6, 2008Publication date: September 29, 2011Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Yun Zong, Mingyong Han, Wolfgang Knoll
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Publication number: 20110129944Abstract: Disclosed is a water soluble nanocrystal having a core comprising at least one metal M1 selected from an element of subgroup IIb, subgroup VIIa, subgroup VI11a, subgroup 1b, subgroup IV, main group II or main group III of the periodic system of the elements (PSE), at least one element A selected from an element of the main group V or VI of the periodic system of the elements, wherein a capping reagent is attached to the surface of the core of the nanocrystal, and wherein the capping reagent forms a host guest complex with a water soluble host molecule.Type: ApplicationFiled: January 17, 2005Publication date: June 2, 2011Applicant: Agency for Science, Technology and ResearchInventors: Fuke Wang, Mingyong Han
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Publication number: 20110033368Abstract: Methods of forming a nanocrystal are provided. The nanocrystal may be a binary nanocrystal of general formula M1A or of general formula M1O, a ternary nanocrystal of general formula M1M2A, of general formula M1AB or of general formula M1M2O or a quaternary nanocrystal of general formula M1M2AB. M1 is a metal of Groups II-IV, Group VII or Group VIII of the PSE. A is an element of Group VI or Group V of the PSE. O is oxygen. A homogenous reaction mixture in a non-polar solvent of low boiling point is formed, that includes a metal precursor containing the metal M1 and, where applicable M2. For an oxygen containing nanocrystal the metal precursor contains an oxygen donor. Where applicable, A is also included in the homogenous reaction mixture. The homogenous reaction mixture is under elevated pressure brought to an elevated temperature that is suitable for forming a nanocrystal.Type: ApplicationFiled: October 3, 2008Publication date: February 10, 2011Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Enyi Ye, Yin Win Khin, Mingyong Han
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Publication number: 20100298504Abstract: Disclosed are an amphiphilic polymer, its synthesis and uses thereof. The polymer has a hydrocarbon backbone with —COOH side groups. It further has first aliphatic moieties with a main chain of about 3 to about 20 carbon atoms and 0 to about 3 heteroatoms, and second aliphatic moieties that have a main chain of about 3 to about 80 carbon atoms and about 2 to about 40 heteroatoms. The second aliphatic moieties have a copolymerisable group. In the synthesis a maleic anhydride polymer of formula (I) where n is an integer from about 10 to about 10000 and R1 is H or methyl, is reacted with a monofunctional compound with an alkyl chain of about 3 to about 20 carbon atoms and 0 to about 2 heteroatoms, and with an at least bifunctional compound with an alkyl chain of about 3 to about 80 carbon atoms and 0 to about 40 heteroatoms. The functional group of the monofunctional compound and one functional group of the at least bifunctional compound can form a linkage with an anhydride.Type: ApplicationFiled: September 19, 2008Publication date: November 25, 2010Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Dominik Janczewski, Nikodem Tomczak, Yin Win Khin, Mingyong Han, Julius Vancso
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Publication number: 20090098663Abstract: Disclosed is a water soluble nanocrystal comprising a nanocrystal core comprising at least one metal M1 selected from an element of main group II, subgroup VIIA, subgroup VIIIA, subgroup IB, subgroup IIB, main group III or main group IV of the periodic system of the elements (PSE), at least one element A selected from main group V or main group VI of the PSE, a capping reagent attached to the surface of the core of the nanocrystal, and a water soluble polymer covalently coupled with the capping reagent to form a water soluble polymer shell over the nanocrystal core. Also disclosed are compositions comprising such nanocrystals and uses of such nanocrystals.Type: ApplicationFiled: May 4, 2005Publication date: April 16, 2009Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Mingyong Han, Fuke Wang
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Publication number: 20090042032Abstract: The invention relates to a water soluble nanocrystal with a nanocrystal core comprising at least one metal M1 selected form an element of main group II, VIIA, subgroup VIIA, subgroup IB, subgroup IIB, main group III or main group IV of the periodic system of the elements (PSE), at least one element A selected from main group V or main group VI of the PSE, a capping reagent attached to the surface of the core of the nanocrystal, said capping reagent having at least two coupling groups, and a second layer comprising a low molecular weight coating reagent having at least two coupling moieties covalently coupled with the coating reagent, and at least one water soluble group for conferring water solubility to the second layer.Type: ApplicationFiled: May 4, 2005Publication date: February 12, 2009Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Mingyong Han, Fuke Wang
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Patent number: 7485488Abstract: A metal oxide nanostructure is formed by oxidizing metallic metal in the presence of a solution containing a liquid ligand to form a metal-ligand complex, and decomposing the metal-ligand complex to form the metal oxide nanostructure. The metal-ligand complex can be a complex of zinc or copper with formamide. In one form, the nanostructure forms ZnO nanorods having a diameter of 10 to 1000 nm, where the nanorods having a hexagonal crystallographic morphology, and the nanorods are oriented perpendicular to a substrate.Type: GrantFiled: April 13, 2005Date of Patent: February 3, 2009Assignee: Agency for Science, Technology and ResearchInventors: Mingyong Han, Zhongping Zhang
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Publication number: 20080305175Abstract: There is disclosed a method of making a micro-container. The method comprises the step of evaporating a swelling agent solution absorbed in a polymer micro-particle to form an inner void therein. The evaporating step is undertaken under conditions to form a conduit extending through the shell wall of said micro-particle and into the inner void.Type: ApplicationFiled: November 29, 2007Publication date: December 11, 2008Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Yubo Wang, Wei Zheng, Mingyong Han, Kaiyu Wang
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Publication number: 20070161043Abstract: The present invention provides a method of preparing a multicolor quantum dot-tagged bead, a multicolor quantum dot-tagged bead, a conjugate thereof, and a composition comprising such a bead or conjugate. Additionally, the present invention provides a method of making a conjugate thereof and methods of using a conjugate for multiplexed analysis of target molecules.Type: ApplicationFiled: December 4, 2006Publication date: July 12, 2007Applicant: Advanced Research and Technology Institute, Inc.Inventors: Shuming Nie, Xiaohu Gao, Mingyong Han
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Patent number: 7056471Abstract: The present invention relates to nanocrystals consisting of a homogeneous ternary or quaternary alloy having the composition M11-xM2xA and M11-xM2xAyB1-y, respectively, a process for its production, as well as to uses of such nanocrystals such as as short wavelength light-emitting devices, and in the detection of analytes, in particular biomolecules.Type: GrantFiled: December 16, 2002Date of Patent: June 6, 2006Assignee: Agency for Science Technology & ResearchInventors: Mingyong Han, Xinhua Zhong, Wolfgang Knoll
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Publication number: 20060110279Abstract: The present invention relates to nanocrystals consisting of a homogeneous ternary or quaternary alloy having the composition M11-xM2xA and M11-xM2xAyB1-y, respectively, a process for its production, as well as to uses of such nanocrystals such as as short wavelength light-emitting devices, and in the detection of analytes, in particular biomolecules.Type: ApplicationFiled: December 16, 2002Publication date: May 25, 2006Inventors: Mingyong Han, Xinhua Zhong, Wolfgang Knoll
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Publication number: 20050255629Abstract: A metal oxide nanostructure is formed by oxidizing metallic metal in the presence of a solution containing a liquid ligand to form a metal-ligand complex, and decomposing the metal-ligand complex to form the metal oxide nanostructure. The metal-ligand complex can be a complex of zinc or copper with formamide. In one form, the nanostructure forms ZnO nanorods having a diameter of 10 to 1000 nm, where the nanorods having a hexagonal crystallographic morphology, and the nanorods are oriented perpendicular to a substrate.Type: ApplicationFiled: April 13, 2005Publication date: November 17, 2005Inventors: Mingyong Han, Zhongping Zhang
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Publication number: 20030148544Abstract: The present invention provides a method of preparing a multicolor quantum dot-tagged bead, a multicolor quantum dot-tagged bead, a conjugate thereof, and a composition comprising such a bead or conjugate. Additionally, the present invention provides a method of making a conjugate thereof and methods of using a conjugate for multiplexed analysis of target molecules.Type: ApplicationFiled: June 28, 2002Publication date: August 7, 2003Applicant: Advanced Research and Technology Institute, Inc.Inventors: Shuming Nie, Xiaohu Gao, Mingyong Han