Patents by Inventor Mingyu HU

Mingyu HU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OLIGOSACCHARIDE LINKER, LINKER-PAYLOAD COMPRISING THE SAME AND GLYCAN CHAIN-REMODELED ANTIBODY-DRUG CONJUGATE, PREPARATION METHODS AND USES THEREOF
    Publication number: 20240082419
    Abstract: The present disclosure further relates to a linker-payload compound including an oligosaccharide group, especially a disaccharide group, where the oligosaccharide group is linked to the remainder of the compound by an amide bond. The present disclosure further relates to an antibody-drug conjugate (ADC) containing the linker-payload compound, where the glycan chain in an antibody is remodeled with the oligosaccharide moiety in the linker-payload compound. The present disclosure further relates to preparation methods and use of the above-mentioned substances.
    Type: Application
    Filed: September 18, 2023
    Publication date: March 14, 2024
    Inventors: Gang QIN, Meijun XIONG, Mingyu HU
  • LINKERS, CONJUGATES AND APPLICATIONS THEREOF
    Publication number: 20240066141
    Abstract: The present disclosure relates to a linker molecule for targeting molecule-drug conjugate, and the corresponding conjugate, the preparation and use thereof.
    Type: Application
    Filed: September 8, 2023
    Publication date: February 29, 2024
    Inventors: Gang QIN, Paul H. SONG, Mingyu HU
  • EXATECAN DERIVATIVES, LINKER-PAYLOADS, AND CONJUGATES AND THEREOF
    Publication number: 20240018159
    Abstract: The present disclosure relates to the biopharmaceutical field, in particular, Exatecan derivatives, linker-payloads, and conjugates and thereof antibody-drug conjugates, and the corresponding preparing process and use thereof.
    Type: Application
    Filed: August 22, 2023
    Publication date: January 18, 2024
    Inventors: Gang QIN, Tony Yantao ZHANG, Guangming CHEN, Paul H. SONG, Boyu ZHONG, Mingyu HU
  • Linkers, conjugates and applications thereof
    Patent number: 11826432
    Abstract: The present disclosure relates to a linker molecule for targeting molecule-drug conjugate, and the corresponding conjugate, the preparation and use thereof.
    Type: Grant
    Filed: April 14, 2022
    Date of Patent: November 28, 2023
    Assignee: GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD.
    Inventors: Gang Qin, Paul H. Song, Mingyu Hu
  • Exatecan derivatives, linker-payloads, and conjugates and thereof
    Patent number: 11814394
    Abstract: The present disclosure relates to the biopharmaceutical field, in particular, Exatecan derivatives, linker-payloads, and conjugates and thereof antibody-drug conjugates, and the corresponding preparing process and use thereof.
    Type: Grant
    Filed: November 8, 2022
    Date of Patent: November 14, 2023
    Assignee: GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD.
    Inventors: Gang Qin, Tony Yantao Zhang, Guangming Chen, Paul H. Song, Boyu Zhong, Mingyu Hu
  • EXATECAN DERIVATIVES, LINKER-PAYLOADS, AND CONJUGATES AND THEREOF
    Publication number: 20230271977
    Abstract: The present disclosure relates to the biopharmaceutical field, in particular, Exatecan derivatives, linker-payloads, and conjugates and thereof antibody-drug conjugates, and the corresponding preparing process and use thereof.
    Type: Application
    Filed: November 8, 2022
    Publication date: August 31, 2023
    Inventors: Gang QIN, Tony Yantao ZHANG, Guangming CHEN, Paul H. SONG, Boyu ZHONG, Mingyu HU
  • LINKERS, CONJUGATES AND APPLICATIONS THEREOF
    Publication number: 20220395581
    Abstract: The present disclosure relates to a linker molecule for targeting molecule-drug conjugate, and the corresponding conjugate, the preparation and use thereof.
    Type: Application
    Filed: April 14, 2022
    Publication date: December 15, 2022
    Inventors: Gang QIN, Paul H. SONG, Mingyu HU