Abstract: A method of modulating an optical camera communication (OCC) signal by an OCC transmission node in an OCC system includes acquiring a binary data signal, grouping the binary data signal for every k bits to convert the binary data signal into a global phase shift signal having an integer value from 0 to M?1 (=2k?1), generating a data signal group by mapping the global phase shift signal to first to Mth mapping sequences in the form of an n*M/2-bit sequence based on a preset symbol group mapping table, generating a pulse wave signal by modulating the data signal group, and blinking each of a plurality of light sources included in the OCC transmission node according to the pulse wave signal. Accordingly, performance of the communication system may be improved.

Abstract: The invention relates to a method for generating a cardiac tissue mimetic, comprising the steps of mixing cardiomyocytes (CM) and fibroblasts (FB) at a ratio from 2.5:1 to 10:1, thereby providing a first mixture, incubating said first mixture, such that said cardiomyocytes and said fibroblasts form a spherical structure, adding endothelial cells (EC) to said spherical structure at a ratio of cardiomyocytes (CM) to endothelial cells (EC) from 1.5:1 to 4:1, thereby providing a second mixture, and incubating said second mixture, such that a cardiac tissue mimetic is formed. The invention further relates to a cardiac tissue mimetic comprising cardiomyocytes (CM), endothelial cells (EC), and fibroblasts (FB), wherein said cardiac tissue mimetic comprises sarcomeric structures and vascular structures. Further aspects of the invention are the cardiac tissue mimetic for use in a method for heart tissue repair or replacement and a method for screening a compound using a cardiac tissue mimetic.