Abstract: The present invention relates to methods of selecting a subject with cancer for treatment, screening a test molecule for use as a cancer therapeutic, and treating a subject with cancer, as well as compositions for treating cancer.

Abstract: Various techniques are described for platform management of integrated access of public and privately-accessible datasets utilizing federated query generation and query schema rewriting optimization, including receiving at a dataset access platform a query formatted according to a first data schema, generating a copy of the query, saving the query and the copy to a datastore, parsing the copy of the query in the first schema using an inference engine, determining whether the query comprises data associated with an access control condition associated with accessing the dataset, the access control condition being configured to indicate whether the query is permitted to access the dataset, and rewriting, using a proxy server, the copy of the query in a second schema by converting the copy of the query into a triple associated with the query and another triple associated with the access control condition.

Abstract: Various embodiments relate generally to data science and data analysis, computer software and systems, and wired and wireless network communications to provide an interface between repositories of disparate datasets and computing machine-based entities that seek access to the datasets, and, more specifically, to a computing and data storage platform that facilitates consolidation of one or more datasets, whereby a collaborative data layer and associated logic facilitate, for example, efficient access to, and implementation of, collaborative datasets. In some examples, a method may include receiving a dataset having a data format into a dataset ingestion controller configured to form a collaborative dataset, interpreting data of the dataset against data classifications at an inference engine to derive at least an inferred attribute, associating the data with annotative data identifying the inferred attribute, and converting the dataset at a format converter to form an atomized dataset.

Abstract: Describes are support elements for a sole of a shoe, in particular a sports shoe, a sole and a shoe with such a support element, as well as a method for the manufacture of a support element. As examples, the support element includes a first partial member formed of a first material, and a second partial member formed of a second material. The first partial member is mechanically joined to the second partial member in a connection region, wherein the connection region is configured to allow the first partial member to rotate or slide relative to the second partial member. The first partial member, the second partial member, and the connection region can be co-molded and joined together in a single fabricating step.

Abstract: Various techniques are described for platform management of integrated access of public and privately-accessible datasets utilizing federated query generation and query schema rewriting optimization, including receiving at a dataset access platform a query formatted according to a first data schema, generating a copy of the query, saving the query and the copy to a datastore, parsing the copy of the query in the first schema using an inference engine, determining whether the query comprises data associated with an access control condition associated with accessing the dataset, the access control condition being configured to indicate whether the query is permitted to access the dataset, and rewriting, using a proxy server, the copy of the query in a second schema by converting the copy of the query into a triple associated with the query and another triple associated with the access control condition.

Abstract: Various embodiments relate generally to data science and data analysis, computer software and systems, and wired and wireless network communications to provide an interface between repositories of disparate datasets and computing machine-based entities that seek access to the datasets, and, more specifically, to a computing and data storage platform that facilitates consolidation of one or more datasets, whereby a collaborative data layer and associated logic facilitate, for example, efficient access to, and implementation of, collaborative datasets. In some examples, a system may include an atomized workflow loader configured to receive an atomized dataset to load into a data store, and to determine resource requirements data to describe at least one resource requirement. The atomized workflow loader may be further configured to select a data store type based on a resource requirement, and perform a load operation of the atomized dataset as a function of the data store type.

Abstract: Flexible yet efficient “find” operations search source code for matches to a general pattern after a developer provides an example string that matches the pattern, without requiring the developer to write a regular expression or script that will implement the desired pattern. Example-driven find-replace functionality uses regular expressions or other pattern match codes, and scripts or other transforms, which are synthesized automatically from examples provided by a developer. This technology allows the developer to focus on workflow inside an integrated development environment instead of breaking focus to search for external documentation, or unfortunately foregoing the flexibility and power of regular expressions and scripts. Synthesizer outputs may be directly or indirectly ranked through user feedback, allowing their refinement. Find match generality may be controlled, e.g., by specifying regex star positions or star counts. Entry of guiding examples may be assisted by autocompletion.

Abstract: Provided herein are friction reducer formulations including a formate salt and an inverting surfactant, and methods of manufacturing such formulations. Methods of using the friction reducer formulations, such as for treating subterranean formations, are also provided.

Abstract: Various embodiments relate generally to data science and data analysis, computer software and systems, and wired and wireless network communications to provide an interface between repositories of disparate datasets and computing machine-based entities that seek access to the datasets, and, more specifically, to a computing and data storage platform that facilitates consolidation of one or more datasets, whereby a collaborative data layer and associated logic facilitate, for example, efficient access to, and implementation of, collaborative datasets. In some examples, a method may include receiving data representing a query of a consolidated dataset that may include datasets formatted atomized datasets, analyzing the query to classify portions of the query to form classified query portions, partitioning the query into sub-queries as a function of a classification type for each of the classified query portions, and retrieving data representing a query result from distributed data repositories.

Abstract: A method for monitoring a cable harness. In the method, at least one value of at least one electrical variable in the cable harness is acquired and at least one signal, which represents this at least one value, is transmitted to at least one evaluator. A number of containers, which in turn represent a value range for the allocated electrical variable in each case, is allocated to each evaluator. The at least one signal is evaluated in such a way that the acquired values are allocated to the containers while taking the respective value range into account. The values allocated to the container are counted in each container. If a threshold value allocated to the container is exceeded, an action is triggered.

Abstract: A method for monitoring an electrical system of a motor vehicle. A safety-related electrical consumer and possibly further electrical consumers are supplied by an energy accumulator. At least one model of the vehicle electrical system is provided which represents the safety-related electrical consumer and corresponding lines with associated line resistances and connection to the energy accumulator.

Abstract: Describes are support elements for a sole of a shoe, in particular a sports shoe, a sole and a shoe with such a support element, as well as a method for the manufacture of a support element. As examples, the support element includes a first partial member formed of a first material, and a second partial member formed of a second material. The first partial member is mechanically joined to the second partial member in a connection region, wherein the connection region is configured to allow the first partial member to rotate or slide relative to the second partial member. The first partial member, the second partial member, and the connection region can be co-molded and joined together in a single fabricating step.

Abstract: Methods and systems are described herein for generating dynamic conversational responses. For example, dynamic conversational responses may facilitate an interactive exchange with users. Therefore, the methods and systems used specialized methods to enriched data that may be indicative of a user's intent prior to processing that data through the machine learning model, as well as a specialized architecture for the machine learning models that take advantage of the user interface format.

Abstract: Methods and systems are described herein for generating dynamic conversational responses. For example, dynamic conversational responses may facilitate an interactive exchange with users. Therefore, the methods and systems used specialized methods to enriched data that may be indicative of a user's intent prior to processing that data through the machine learning model, as well as a specialized architecture for the machine learning models that take advantage of the user interface format.

Abstract: Methods and systems are described for generating dynamic interface options using machine learning models. The dynamic interface options may be generated in real time and reflect the likely goals and/or intents of a user. The machine learning model may provide these features by interpreting multi-modal feature inputs. For example, the machine learning model may include a first machine learning model, wherein the first machine learning model comprises a convolutional neural network, and a second machine learning model, wherein the second machine learning model performs a Weight of Evidence (WOE) analysis.

Abstract: Methods and systems are described for generating dynamic conversational responses using two-tier machine learning models. The dynamic conversational responses may be generated in real time and reflect the likely goals and/or intents of a user. The two-tier machine learning model may include a first tier that determines an intent cluster based on a feature input, and a second tier that determines a specific intent from the cluster.

Abstract: Methods and systems are described for generating dynamic interface options using machine learning models. The dynamic interface options may be generated in real time and reflect the likely goals and/or intents of a user. The machine learning model may provide these features by interpreting multi-modal feature inputs. For example, the machine learning model may include a first machine learning model, wherein the first machine learning model comprises a convolutional neural network, and a second machine learning model, wherein the second machine learning model performs a Weight of Evidence (WOE) analysis.

Abstract: Improved cushioning elements for sports apparel, in particular for soles for sports shoes, are described. A cushioning element for sports apparel with a first deformation element is provided. The deformation element includes a plurality of randomly arranged particles of an expanded material, wherein there are first voids within the particles and/or between the particles.

Abstract: A method for synchronizing signals of a plurality of participants. A relationship between the signals is given by a physical relation. The signals are each filtered with a first filter in order to determine a shift between the signals. The determined shift is a measure of the phase shift between the signals. The shift is subsequently eliminated by filtering the signals respectively with a second filter.

Abstract: Improved cushioning elements for sports apparel, in particular for soles for sports shoes, are described. A cushioning element for sports apparel with a first deformation element is provided. The deformation element includes a plurality of randomly arranged particles of an expanded material, wherein there are first voids within the particles and/or between the particles.