Abstract: A moving coil brushless motor including an actuator having a stator and a rotor. The stator includes a cylindrical array of permanent magnets. The rotor includes a coil assembly having a plurality of coils interposed between a stator back plate and the permanent magnet array. The coil assembly rotates relative to the array of permanent magnets. A center shaft is disposed to rotate about a longitudinal axis. A cylindrical transformer is disposed within an interior space circumscribed by the stator back plate and includes a primary side and a secondary side. The primary side includes a primary coil and the secondary side includes a secondary coil magnetically coupled to the primary coil. Primary electronics are in communication with secondary electronics attached to the center shaft. The secondary electronics are configured to receive power from the secondary coil and to provide current to the actuator.

Abstract: A stationary electromagnetic inspection (EMI) apparatus and method are disclosed which includes a base; a plurality of hydraulic clamping rollers, connected to that base, operable to move a test pipe forward and backward in a translational direction only; a transverse flaw detection module comprising a plurality of sensor arms each equipped with rows of magnetic sensor arrays arranged in a stagger manner along an axis of a test pipe; and a longitudinal flaw detection module comprising magnetizers and magnetic sensor arrays each respectively arranged orthogonal to one another.

Abstract: Described examples include a method having steps of laying out at least two conductors and modeling conductor current through the at least two conductors to determine a current density in the at least two conductors. The method also has steps of revising the at least two conductors as adjusted conductors to add conductive material to areas of the conductor where the modeling conductor current shows above average current density; fabricating the adjusted conductors; and mounting a die to the adjusted conductors.

Abstract: The present invention relates to a self-designed single-nucleotide polymorphism chip and a method of computing polygenic risk score (PRS) for a given population using the self-designed single-nucleotide polymorphism chip. The self-designed single-nucleotide polymorphism chip using LmTag algorithm comprises the following modules: a pairwise imputation score computation module; a functional score computation module; and a tag SNP selection module.

Abstract: A linear actuator includes a magnet housing having first and second planar sides, a front plate and a rear plate, and a base plate covering a channel defined by the magnet housing. A first plurality of magnets is secured to the first planar side and a second plurality of magnets is secured to the second planar side. A linear guide slidably secured to an inner surface of the base plate. A piston assembly has a piston element attached to the linear guide. The piston assembly includes a shaft and a printed circuit board attached to the piston element. The printed circuit board defines a controller and a printed coil assembly. A flex cable is electrically connected to the printed circuit board. The piston assembly is disposed to move linearly during operation of the linear actuator.

Abstract: A stationary electromagnetic inspection (EMI) apparatus and method are disclosed which includes a base; a plurality of hydraulic clamping rollers, connected to that base, operable to move a test pipe forward and backward in a translational direction only; a transverse flaw detection module comprising a plurality of sensor arms each equipped with rows of magnetic sensor arrays arranged in a stagger manner along an axis of a test pipe; and a longitudinal flaw detection module comprising magnetizers and magnetic sensor arrays each respectively arranged orthogonal to one another.

Abstract: A system and method for routing a fleet of vehicles, the vehicles being based across a plurality of depots. The system and method can determine an optimal route by decomposing the optimisation problem into a plurality of sub-problems, optimising each of the sub-problems and then re-combining the optimised sub-problems to obtain a solution to the routing problem. The solution leads to a more efficient routing of the vehicle fleet, and improves accuracy, efficiency, and functionality of the multi-depot vehicle network system.

Abstract: A unit for the regulation for control of a fluid pressure, having at least one housing section and a switching film connected to the at least one housing section. A chemically inert, non-rubber-like PTFEswitching film switching film is disposed in the valve housing and switches at pressure differences of 1 mbar to 250 mbar for regulating, opening or blocking a flow of a fluid from the inlet to the outlet. The switching film is formed of a fluorine and carbon containing polymer material. The switching film has a plate-shaped flat body with a bending region and has a central closure region surrounded by the bending region. The bending region, when switching the switching film, moves the central closure region relative to a valve seat of the valve housing in an axial direction of the plate-shaped flat body toward or away from the valve seat by a stretch free or low-stretch bending movement.

Abstract: The present invention relates to a method for estimating the effectiveness of treatment with an anti-CD20 agent in a patient with rheumatoid arthritis and who has had an inadequate response to at least one prior biotherapy, consisting in analysing a biological sample of said patient for the expression of a set of biomarkers, the results of which make it possible to determine whether said agent is a treatment that will engender a beneficial response for said patient. The present invention also relates to a system for estimating the effectiveness of said treatment in said patient comprising means for measuring or receiving data, the expression level of said biomarkers and means for processing these data configured to estimate said effectiveness of said treatment in said patient.

Abstract: A moving coil brushless motor including an actuator having a stator and a rotor. The stator includes a cylindrical array of permanent magnets. The rotor includes a coil assembly having a plurality of coils interposed between a stator back plate and the permanent magnet array. The coil assembly rotates relative to the array of permanent magnets. A center shaft is disposed to rotate about a longitudinal axis. A cylindrical transformer is disposed within an interior space circumscribed by the stator back plate and includes a primary side and a secondary side. The primary side includes a primary coil and the secondary side includes a secondary coil magnetically coupled to the primary coil. Primary electronics are in communication with secondary electronics attached to the center shaft. The secondary electronics are configured to receive power from the secondary coil and to provide current to the actuator.

Abstract: The present invention relates to a method for estimating the effectiveness of treatment with an anti-TNF? agent in a patient with rheumatoid arthritis and who has had an inadequate response to at least one prior biotherapy, consisting in analysing a biological sample of said patient for the expression of a set of biomarkers, the results of which make it possible to determine whether said agent is a treatment that will engender a beneficial response for said patient. The present invention also relates to a system for estimating the effectiveness of said treatment in said patient comprising means for measuring or receiving data, the expression level of said biomarkers and means for processing these data configured to estimate said effectiveness of the treatment in said patient.

Abstract: A unit (10) for the regulation or control of a fluid pressure, having at least one housing section (13, 14) and a switching film (22) connected to the at least one housing section (13, 14) for switching at pressure differentials relative to an ambient pressure acting on the switching film (22), and for the regulation, release or blocking of a flow of the fluid between an inlet (28) and a discharge (30) for the fluid. The switching film (22) is made out of a polymer material having fluorine and carbon, in particular a thermoplastic having fluorine and carbon. In this arrangement, a hole cross-section (40) of the at least one housing section (13, 14) is closed off by the switching film (22).

Abstract: The invention relates to a solution for diagnosing an operational condition of at least one device of an elevator car. The solution comprises the at least one device, an image capturing device, at least one reflective surface arranged to a position in an elevator car forming a path of reflection between the image capturing device and a portion of the at least one device, and a control device, In the solution the at least one device is caused to set the operating state and the image capturing device is configured to capture an image at least on the portion of the at least one device seen by the image capturing device through the at least one reflective surface, the image data is analyzed and based on that the operational condition of the device is concluded.

Abstract: A unit for the regulation for control of a fluid pressure, having at least one housing section and a switching film connected to the at least one housing section. A chemically inert, non-rubber-like PTFEswitching film switching film is disposed in the valve housing and switches at pressure differences of 1 mbar to 250 mbar for regulating, opening or blocking a flow of a fluid from the inlet to the outlet. The switching film is formed of a fluorine and carbon containing polymer material. The switching film has a plate-shaped flat body with a bending region and has a central closure region surrounded by the bending region. The bending region, when switching the switching film, moves the central closure region relative to a valve seat of the valve housing in an axial direction of the plate-shaped flat body toward or away from the valve seat by a stretch free or low-stretch bending movement.

Abstract: An external M.2 solid-state drive dock with local and network interfaces is disclosed. The dock includes an enclosure with apertures through which M.2 solid-state drives can be received. A circuit board is mounted within the enclosure that includes M.2 socket connectors for receiving the M.2 solid-state drives. The circuit board also includes a storage controller coupled to the M.2. socket connectors. A local interface controller is coupled to the storage controller for providing a local interface, such as a USB-C interface, to the M.2 solid-state drives to host computers. A network controller is also coupled to the storage controller for providing network interfaces, such as wired and/or wireless network interfaces, for accessing the M.2. solid-state drives. The storage controller can receive storage requests from the local interface controller and the network interface controller and provide the storage requests to the M.2 solid-state drives.

Abstract: A unit (10) for the regulation or control of a fluid pressure, having at least one housing section (13, 14) and a switching film (22) connected to the at least one housing section (13, 14) for switching at pressure differentials relative to an ambient pressure acting on the switching film (22), and for the regulation, release or blocking of a flow of the fluid between an inlet (28) and a discharge (30) for the fluid. The switching film (22) is made out of a polymer material having fluorine and carbon, in particular a thermoplastic having fluorine and carbon. In this arrangement, a hole cross-section (40) of the at least one housing section (13, 14) is closed off by the switching film (22).

Abstract: The disclosure relates to a method for estimating the effectiveness of treatment with a T-lymphocyte cell co-stimulation modulator agent in a patient with rheumatoid arthritis and who has had an inadequate response to prior biotherapy, consisting in analysing a biological sample of said patient for the expression of a set of biomarkers, the results of which make it possible to determine whether said modulator agent is a treatment that will engender a beneficial response for said patient. The disclosure also relates to a system for estimating the effectiveness of said treatment in said patient comprising means for measuring or receiving data concerning the expression level of said biomarkers and means for processing these data configured to estimate said effectiveness of said treatment in said patient.

Abstract: A unit (10) for the regulation or control of a fluid pressure, having at least one housing section (13, 14) and a switching film (22) connected to the at least one housing section (13, 14) for switching at pressure differentials relative to an ambient pressure acting on the switching film (22), and for the regulation, release or blocking of a flow of the fluid between an inlet (28) and a discharge (30) for the fluid. The switching film (22) is made out of a polymer material having fluorine and carbon, in particular a thermoplastic having fluorine and carbon. In this arrangement, a hole cross-section (40) of the at least one housing section (13, 14) is closed off by the switching film (22).

Abstract: A unit (10) for the regulation or control of a fluid pressure, having at least one housing section (13, 14) and a switching film (22) connected to the at least one housing section (13, 14) for switching at pressure differentials relative to an ambient pressure acting on the switching film (22), and for the regulation, release or blocking of a flow of the fluid between an inlet (28) and a discharge (30) for the fluid. The switching film (22) is made out of a polymer material having fluorine and carbon, in particular a thermoplastic having fluorine and carbon. In this arrangement, a hole cross-section (40) of the at least one housing section (13, 14) is closed off by the switching film (22).

Abstract: An external M.2 solid-state drive dock with local and network interfaces is disclosed. The dock includes an enclosure with apertures through which M.2 solid-state drives can be received. A circuit board is mounted within the enclosure that includes M.2 socket connectors for receiving the M.2 solid-state drives. The circuit board also includes a storage controller coupled to the M.2. socket connectors. A local interface controller is coupled to the storage controller for providing a local interface, such as a USB-C interface, to the M.2 solid-state drives to host computers. A network controller is also coupled to the storage controller for providing network interfaces, such as wired and/or wireless network interfaces, for accessing the M.2. solid-state drives. The storage controller can receive storage requests from the local interface controller and the network interface controller and provide the storage requests to the M.2 solid-state drives.