Patents by Inventor Minho Roh

Minho Roh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for fine-tuning gene expression levels using synthetic regulatory SRNA
    Patent number: 10196644
    Abstract: The present invention relates to a method for fine-tuning gene expression levels using a synthetic regulatory sRNA in a prokaryotic cell. The present invention can simultaneously, easily, and quickly apply various target gene combinations to various strains without gene deletion through the synthetic regulatory sRNA for regulating gene expression and is therefore very suitable for measuring the metabolizability of each strain and selecting an optimum strain. In addition, the method has the advantages of easily and quickly selecting a target gene for the inhibition of gene expression and expressing the gene thus selected to a desired degree and thus can be used in producing recombinant strains for the efficient production of various metabolites and establishing a method for the efficient production and is therefore very useful.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: February 5, 2019
    Assignee: Korea Advanced Institute of Science and Technology
    Inventors: Sang Yup Lee, Minho Roh, Seung Min Yoo
  • METHOD FOR FINE-TUNING GENE EXPRESSION LEVELS USING SYNTHETIC REGULATORY SRNA
    Publication number: 20170130235
    Abstract: The present invention relates to a method for fine-tuning gene expression levels using a synthetic regulatory sRNA in a prokaryotic cell. The present invention can simultaneously, easily, and quickly apply various target gene combinations to various strains without gene deletion through the synthetic regulatory sRNA for regulating gene expression and is therefore very suitable for measuring the metabolizability of each strain and selecting an optimum strain. In addition, the method has the advantages of easily and quickly selecting a target gene for the inhibition of gene expression and expressing the gene thus selected to a desired degree and thus can be used in producing recombinant strains for the efficient production of various metabolites and establishing a method for the efficient production and is therefore very useful.
    Type: Application
    Filed: June 11, 2014
    Publication date: May 11, 2017
    Applicant: Korea Advanced Institute of Science and Technology
    Inventors: Sang Yup Lee, Minho Roh, Seung Min Yoo