Abstract: Systems and methods for using texture parameters to predict human interpretation of images to design, modify, or optimize an imaging system or an imaging process. According to embodiments, a method includes receiving image data; calculating one or more texture parameters based on the image data; and predicting performance of a human observer in detecting a signal or object in the image data obtained by the imaging system or processed by the imaging process based on the one or more texture parameters. The method may include designing, optimizing, or modifying parameters of the imaging system or the imaging process based on the predicted performance of a human observer or interpreter in detecting the signal or object in the image data. The method may include assigning weights to two or more texture parameters based on a given detection task, such as detecting explosives in luggage or finding a tumor in tomographic images.

Abstract: A system and method for single step and motionless x-ray phase contrast imaging. In one embodiment, a system for single step x-ray imaging includes a clinical x-ray source, a first coded aperture mask, a second coded aperture mask, and a photon counting spectral detector. The first coded aperture mask is disposed between the x-ray source and an object to be imaged. The photon counting spectral detector is disposed to detect x-rays passing through the object. The second coded aperture mask is disposed between the object to be imaged and the photon counting spectral detector. The system can provide, from a single acquisition step, an absorption image, a phase image, and differential phase image.

Abstract: A system and method for single step x-ray phase contrast imaging. In one embodiment, a method for single step x-ray phase contrast imaging includes illuminating an object to be imaged with x-rays. The x-rays passing through the object are detected by a spectral detector. Image data derived from the detected x-rays is provided to an x-ray image processor. A phase image is generated based on the image data.

Abstract: A system and method for single step and motionless x-ray phase contrast imaging. In one embodiment, a system for single step x-ray imaging includes a clinical x-ray source, a first coded aperture mask, a second coded aperture mask, and a photon counting spectral detector. The first coded aperture mask is disposed between the x-ray source and an object to be imaged. The photon counting spectral detector is disposed to detect x-rays passing through the object. The second coded aperture mask is disposed between the object to be imaged and the photon counting spectral detector. The system can provide, from a single acquisition step, an absorption image, a phase image, and differential phase image.

Abstract: A system and method for single step x-ray phase contrast imaging. In one embodiment, a method for single step x-ray phase contrast imaging includes illuminating an object to be imaged with x-rays. The x-rays passing through the object are detected by a spectral detector. Image data derived from the detected x-rays is provided to an x-ray image processor. A phase image is generated based on the image data.