Patents by Inventor Minmin Luo

Minmin Luo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MICROGLIA HAVING CAR AND USE THEREOF
    Publication number: 20250333758
    Abstract: Provided is a recombinant adeno-associated virus (rAAV) vector comprising a nucleic acid molecule encoding a chimeric antigen receptor (CAR) which specifically binds to a central nervous system (CNS) tumor cell, preferably a solid CNS tumor cell. Further provided is a modified cell comprising a chimeric antigen receptor (CAR) which is obtained by transducing the cell with the rAAV vector, and a method for treating a CNS tumor using the rAAV vector or modified cell of the present disclosure.
    Type: Application
    Filed: December 15, 2022
    Publication date: October 30, 2025
    Inventors: Rui Lin, Ting Yan, Minmin Luo
  • RECOMBINANT AAV VECTORS AND USE THEREOF
    Publication number: 20250297279
    Abstract: Provided is a recombinant adeno-associated virus (rAAV) capsid protein, comprising an amino acid sequence of 11 contiguous amino acids X1X2X3X4X5X6X7X8X9X10Q, rAAV vector comprising the same, and the use thereof.
    Type: Application
    Filed: December 15, 2021
    Publication date: September 25, 2025
    Inventors: Rui Lin, Minmin Luo
  • Hybridization chain reaction-based method for amplifying immunosignals
    Patent number: 12258614
    Abstract: The invention provides an antibody-based bioanalytical method, specifically a hybridization Chain Reaction-based Method for Amplifying Immunosignals named immunosignal HCR (isHCR), which combines antibody-antigen interactions with hybridization Chain Reaction (HCR) technology for amplifying immunosignals. The invention also provides a kit for performing the above isHCR.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: March 25, 2025
    Assignee: GenAns Biotechnology Co., Ltd.
    Inventors: Rui Lin, Minmin Luo
  • MULTIPLEXED IMMUNOSIGNAL AMPLIFICATION USING HYBRIDIZATION CHAIN REACTION-BASED METHOD
    Publication number: 20250084454
    Abstract: The invention provides a method for optimizing isHCR for multiplexed labeling, which combines binder-biomolecule interactions with hybridization Chain Reaction (HCR).
    Type: Application
    Filed: November 25, 2024
    Publication date: March 13, 2025
    Inventors: Rui LIN, Minmin LUO
  • OPTOGENETIC VISUAL RESTORATION USING LIGHT-SENSITIVE GQ-COUPLED NEUROPSIN (OPSIN 5)
    Publication number: 20250032577
    Abstract: Provided is an isolated light-sensitive opsin for rapidly, reversibly, and precisely restoring sensitivity to light of the retinal cell through activating Gq signaling.
    Type: Application
    Filed: December 20, 2022
    Publication date: January 30, 2025
    Inventors: Tao Yu, Ruicheng Dai, Danwei Weng, Minmin Luo
  • ULTRA LIGHT-SENSITIVE NEUROPSIN-BASED OPTOGENETIC TOOL FOR ACTIVATING G q-COUPLED SIGNALING AND/OR ACTIVATING CELLS
    Publication number: 20250011391
    Abstract: The present invention relates to an isolated light-sensitive opsin for rapidly, reversibly, and precisely activating Gq signaling and/or activating cells.
    Type: Application
    Filed: December 20, 2022
    Publication date: January 9, 2025
    Inventors: Tao Yu, Ruicheng Dai, Danwei Weng, Minmin Luo
  • Multiplexed immunosignal amplification using hybridization chain reaction-based method
    Patent number: 12188077
    Abstract: The invention provides a method for optimizing isHCR for multiplexed labeling, which combines binder-biomolecule interactions with hybridization Chain Reaction (HCR).
    Type: Grant
    Filed: October 11, 2022
    Date of Patent: January 7, 2025
    Assignee: GenAns Biotechnology Co., Ltd
    Inventors: Rui Lin, Minmin Luo
  • MULTIPLEXED IMMUNOSIGNAL AMPLIFICATION USING HYBRIDIZATION CHAIN REACTION-BASED METHOD
    Publication number: 20230220445
    Abstract: The invention provides a method for optimizing isHCR for multiplexed labeling, which combines binder-biomolecule interactions with hybridization Chain Reaction (HCR).
    Type: Application
    Filed: October 11, 2022
    Publication date: July 13, 2023
    Inventors: Rui LIN, Minmin LUO
  • MULTIPLEXED IMMUNOSIGNAL AMPLIFICATION USING HYBRIDIZATION CHAIN REACTION-BASED METHOD
    Publication number: 20210198715
    Abstract: The invention provides a method for optimizing isHCR for multiplexed labeling, which combines binder-biomolecule interactions with hybridization Chain Reaction (HCR).
    Type: Application
    Filed: January 26, 2018
    Publication date: July 1, 2021
    Inventors: Rui LIN, Minmin LUO
  • HYBRIDIZATION CHAIN REACTION-BASED METHOD FOR AMPLIFYING IMMUNOSIGNALS
    Publication number: 20200377926
    Abstract: The invention provides an antibody-based bioanalytical method, specifically a hybridization Chain Reaction-based Method for Amplifying Immunosignals named immunosignal HCR (isHCR), which combines antibody-antigen interactions with hybridization Chain Reaction (HCR) technology for amplifying immunosignals. The invention also provides a kit for performing the above isHCR.
    Type: Application
    Filed: January 26, 2018
    Publication date: December 3, 2020
    Applicant: NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING
    Inventors: Rui Lin, Minmin Luo