Patents by Inventor Mino Rodolfo Caira

Mino Rodolfo Caira has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INJECTABLE FORMULATION OF A REVERSE TRANSCRIPTASE INHIBITOR FOR THE TREATMENT CANCER
    Publication number: 20130143872
    Abstract: This invention relates to a composition formulated into a parenteral or injectable dosage form for the treatment of cancer, more particularly, this invention relates to a composition formulated into a parenteral dosage form suitable for administration in and around cancerous tissue, the composition including: a pharmaceutically acceptable solvent including from 20% to 100% ethanol (V/V); and a reverse transcriptase inhibitor exhibiting an anti-cancer effect, dissolved in the solvent.
    Type: Application
    Filed: May 31, 2011
    Publication date: June 6, 2013
    Inventors: Nicole Stieger, Wilna Liebenberg, Melgardt Melvin De Villiers, Mino Rodolfo Caira
  • Process for the optical resolution of 3-(p-chlorophenyl)-glutaramide
    Patent number: 6051734
    Abstract: A process for the optical resolution of racemic 3-(p-chlorophenyl)glutaramide (GAM) into its R isomer R--COOH and its S isomer S--COOH, which process includes the steps of either:(1) reacting racemic 3-(p-chlorophenyl)-glutaramide dissolved in a suitable solvent with S-(-)-.alpha.-methylbenzylamine of the formula H.sub.2 N--S'(2) precipitating out of the solution of step (1) R--CO.sub.2.sup.-.H.sub.3.sup.+ N--S';(3) dissolving the precipitate of step (2) in water, with the addition of a suitable acid; and(4) precipitating out of the solution of step (3) R--COOH; or(5) reacting racemic -3-(p-chlorophenyl)-glutaramide dissolved in a suitable solvent with R-(+)-.alpha.-methylbenzylamine of the formula H.sub.2 N--R';(6) precipitating out of the solution of step (5) S--CO.sub.2.sup.-.H.sub.3.sup.+ N--R';(7) dissolving the precipitate of step (6) in water, with the addition of a suitable acid, and(8) precipitating out of the solution of step (7) S--COOH.
    Type: Grant
    Filed: June 19, 1998
    Date of Patent: April 18, 2000
    Assignee: Farmarc Nederland B.V.
    Inventors: Alexander Franciscus Wildervanck, Mino Rodolfo Caira, Janet Lesley Scott, Liugi Renzo Nassimbeni, Rainer Clauss, Barratt Robert Dixon Easter
  • Inclusion complex of beta-cyclodextrin and diclofenac, its preparation and use
    Patent number: 5674854
    Abstract: An inclusion complex of diclofenac, preferably as diclofenac sodium, and an unsubstituted beta-cyclodextrin has the formula 1 molecule of diclofenac to 1 molecule of the unsubstituted beta-cyclodextrin and preferably from 5 to 11 water molecules. The inclusion complex may be formulated as a pharmaceutical composition.
    Type: Grant
    Filed: October 7, 1994
    Date of Patent: October 7, 1997
    Assignee: Farmarc Nederland BV
    Inventors: Mark David Bodley, Mino Rodolfo Caira, Lueta Ann Glintenkamp, Vivienne Jean Griffith, Luigi Renzo Nassimbeni, Douglas George Murray Nicholson, Lawrence John Penkler, Michiel Coenraad Bosch Van Oudtshoorn