Abstract: A theophylline sustained release tablet obtained by coating core granules composed mainly of theophylline with a layer of a coating film composed of a hydrophobic material and a plastic excipient and optionally containing an enteric polymer material to form coated granules and then by compressing the coated granules together with a disintegrating excipient.

Abstract: A cation exchange resin preparation in the dosage form of dry syrups and the like which comprises a cation exchange resin such as polystyrene calcium sulfonate and a gelleing agent such as carboxymethylcellulose sodium (CMC-Na), and may further comprises a binder such as hydroxypropyl cellulose (HPC). The preparation gelates and/or swells without disintegration for a few tens seconds to a minute or so when taken as suspensions in water or the preparation, per se. Therefore, the sandy feel in the mouth and throat, which is a problem in taking the preparation comprising a cation exchange resin alone, is reduced and the taste and easiness in oral administration are both improved.

Abstract: A carrier for immobilization of microorganisms is prepared by impregnating a fabric such as cotton gauze having a mesh size of 10-50 with 20-50% by weight of a vinyl monomer such as ethlene glycol methacrylate and polymerizing the monomer with ionizing radiation to form a polymer coating on the fabric. A microorganism such as Trichoderma reesei is grown in a liquid culture medium in contact with the polymer-coated fabric and the polymer-coated fabric is recovered containing growing cells of the microorganism. The polymer-coated fabric has high air permeability and permits good diffusion of liquid culture medium.