Abstract: Provided is a composition comprising Chlamydomonas reinhardtii or an extract of the Chlamydomonas reinhardtii, wherein the Chlamydomonas reinhardtii or the extract of the Chlamydomonas reinhardtii functions as an antagonist of an adrenergic receptor.

Abstract: An apparatus and method for indicating locus of an ultrasonic probe configured to transmit and receive ultrasonic waves toward a part of a subject wherein a position or movement of the ultrasonic probe is detected, and a locus of the ultrasonic probe on an image of the part of the subject is indicated according to the detected position or movement.

Abstract: A drug ejecting apparatus has an ejection port and an element which generates energy for ejecting a drug from the ejection port; a drug containing unit is connected to the drug ejection apparatus, and contains the drug; a movable wall is attached to an end of the drug containing unit, and is displaced by difference between pressures inside and outside of the drug containing unit; and a control unit displaces the movable wall. The drug ejection apparatus is filled with the drug, and the inside pressure of the drug containing unit is put in a negative pressure state in advance of ejecting of the drug, by displacing the movable wall by means of the control unit.

Abstract: An apparatus and method for indicating locus of an ultrasonic probe configured to transmit and receive ultrasonic waves toward a part of a subject wherein a position or movement of the ultrasonic probe is detected, and a locus of the ultrasonic probe on an image of the part of the subject is indicated according to the detected position or movement.

Abstract: The present invention provides a polyethylene glycol-conjugated erythropoietin (PEG-conjugated EPO) prepared by PEG conjugation on the lysine residue at position 52 of native erythropoietin (native EPO). In order to achieve more sustained efficacy without losing physiological activities of native EPO, a glycoprotein rich in sugar chains, there has been a need to develop a PEG-conjugated EPO with significantly sustained efficacy by introducing a controlled number of PEG molecules at controlled positions. This PEG-conjugated EPO addresses such a need and provides more sustained efficacy.

Abstract: A drug ejecting apparatus comprises a drug ejection apparatus which has an ejection port and an element which generates energy for ejecting a drug from the ejection port; a drug containing unit which is connected to the drug ejection apparatus, and contains the drug; a movable wall which is attached to an end of the drug containing unit, and is displaced by difference between pressures from the inside and outside of the drug containing unit; and a control unit which displaces the movable wall, wherein the drug ejection apparatus is filled with the drug, and inside pressure of the drug containing unit is made into a negative pressure state in advance of ejecting of the drug, by displacing the movable wall by the control unit.

Abstract: The present invention provides a polyethylene glycol-conjugated erythropoietin (PEG-conjugated EPO) prepared by PEG conjugation on the lysine residue at position 52 of native erythropoietin (native EPO). In order to achieve more sustained efficacy without losing physiological activities of native EPO, a glycoprotein rich in sugar chains, there has been a need to develop a PEG-conjugated EPO with significantly sustained efficacy by introducing a controlled number of PEG molecules at controlled positions. This PEG-conjugated EPO addresses such a need and provides more sustained efficacy.

Abstract: The present invention provides a polyethylene glycol-conjugated erythropoietin (PEG-conjugated EPO) prepared by PEG conjugation on the lysine residue at position 52 of native erythropoietin (native EPO). In order to achieve more sustained efficacy without losing physiological activities of native EPO, a glycoprotein rich in sugar chains, there has been a need to develop a PEG-conjugated EPO with significantly sustained efficacy by introducing a controlled number of PEG molecules at controlled positions. This PEG-conjugated EPO addresses such a need and provides more sustained efficacy.

Abstract: Filter has a filter main body, a container, a first counter room, and a second counter room. A counter air is introduced into the first counter room through the counter air discharge valve, and fine particles trapped in the filter main body are removed and transported to the second counter room. Then, the removed fine particles are further transported to a process portion isolated from an exhaust gas passage, and the fine particles are fired in the process portion. Since the process portion is isolated from the exhaust gas passage, the fine particles in the process portion are not returned to the filter main body. Moreover, since the fine particles are transported by the counter air only to the second counter room, it is possible to reduce an amount of the counter air.

Abstract: Filter has a filter main body, a container, a first counter room, and a second counter room. A counter air is introduced into the first counter room through the counter air discharge valve, and fine particles trapped in the filter main body are removed and transported to the second counter room. Then, the removed fine particles are further transported to a process portion isolated from an exhaust gas passage, and the fine particles are fired in the process portion. Since the process portion is isolated from the exhaust gas passage, the fine particles in the process portion is not returned to the filter main body. Moreover, since the fine particles are transported by the counter air only to the second counter room, it is possible to reduce an amount of the counter air.

Abstract: A ballpoint pen refill has an ink-accommodating tube (1) containing an ink (6) having a thixotropic property and a greaselike ink follower (7) capable of moving together with the ink (6) as the ink (6) is consumed so as to be contiguous with the rear end of the ink (6) to prevent the reverse flow of the ink (6). The ink-accommodating tube (1) has a small diameter portion (3) formed at a front side and a large diameter portion (2) having a diameter greater than the diameter of the small diameter portion (3) and extending rearward from the small diameter portion (3). A ballpoint pen tip (5) rotatably holding a ball (4) is inserted in the small diameter portion (3) of the ink-accommodating tube (1). A regulating member (15) has a column (15a) which is press-fitted in the small diameter portion (3). The column (15a) of the regulating member (15) has an inclined end surface (14) at its front end inclined at a predetermined angle to a plane perpendicular to the axis (O) of the ink-accommodating tube (1).

Abstract: A correction pen has a joining mechanism for joining together a front end portion (11) of a barrel (1), and a coupling portion (22) of a head member (2). The joining mechanism is constructed so that an inner cylindrical portion (22b) is pressed in a first coupling section (11a), an annular bead (2a) formed on an outer cylindrical portion (22a) squeezes a second coupling section (11b), and a bead (2c) formed on a step (22c) is pressed against the front end surface (1a) of the first coupling section when an annular ridge (1b) formed on the second coupling section (11b) is fitted in an annular groove (2b) formed in the outer cylindrical portion (22a). A ball holding tube (7) is provided with a ball housing bore (7b) and a connecting bore (7d) formed so that a low step is formed between the ball housing bore and the connecting bore. The edge of the tip of the ball holding tube is rounded. A head member is provided with a spring support portion (2f) for supporting a coil spring (8), provided with slots (2g).

Abstract: A cap is fitted onto an engagement portion of a main body such as that of a writing implement, paint applicator, make-up applicator, or container. An inner wall of the cap is provided with a flexible operating member having a free end capable of bending inward. An oblique guide surface is formed on at least one of the main body and the cap such that the cap can be separated from the main body by pressing the operating member inward.

Abstract: A ceramic honeycomb catalytic converter having a novel canning structure capable of stably retaining a thin-walled ceramic honeycomb catalyst within a metal casing for a long period. A retainer member in the form of a ceramic fiber mat is disposed between an inner peripheral surface of the casing and an outer peripheral surface of the honeycomb catalyst, in a compressed state to generate a surface pressure for retaining the honeycomb catalyst in place. The ceramic fiber mat is composed of heat resistant and non-intumescent ceramic fibers, and has a compression characteristic which is substantially free from a significant increase or decrease over an operative temperature range of the catalytic converter. The casing may be provided with at least one locking member for locking the ceramic fiber mat in a flow direction of exhaust gas passed through the honeycomb catalyst.

Abstract: In a honeycomb catalytic converter having a metal case, a honeycomb catalyst mounted in the metal case, and a securing member used for mounting the honeycomb catalyst in the metal case and arranged between an outer surface of the honeycomb catalyst and an inner surface of the metal case, at lest one of an inlet portion and outlet portion of the honeycomb catalyst has a double cone structure in which an inner cylindrical member is arranged in the metal case. The honeycomb catalytic converter mentioned above can mount the honeycomb catalyst stably in the metal case for a long period of time even when exposed to high temperatures.

Abstract: An exhaust gas recirculation device for an internal combustion engine has a filter for trapping particulates in a recirculation gas, which is arranged in a recirculation gas route, and a device for generating a reverse air flow in which a pure gas flow for the reverse air flow passing through said filter in a reverse direction with respect to a recirculation gas flowing direction in the filter is generated. In the exhaust gas circulation device, the trapped gases are discharged out of the filter by the reverse air flow and are not returned into the internal combustion engine due to an engine exhaust pressure.

Abstract: A preparation containing an aluminum salt of a sucrose sulfate ester (sucralfate) and polyethylene glycol, and a process for preparation of the same are disclosed. Sucralfate is extensively used as a curative for digestive ulcers and has the capability of protecting the substrate protein. Sucralfate is mixed with polyethylene glycol to provide it with improved disintegrability and dispersibility and this renders sucralfate more useful as a medicine.

Abstract: In order to obtain a honeycomb structural body having excellent mechanical strength, which can eliminate a waste use of a catalyst, incomplete cells at an outermost peripheral portion of the honeycomb structural body are sealed selectively by ceramic materials. An incomplete cell does not have a square cross section if the complete cell has a square cross section, and is preferably defined by the cell having an area not more than 90% as that of the complete cell.

Abstract: A ceramic honeycomb catalyst includes a thin-walled honeycomb structural body (10) and a catalytic substance carried by the honeycomb structural body (10). The honeycomb structural body (10) has a number of longitudinally extending flow passages (13) defined by an outer peripheral wall (11) and partition walls (12) with a reduced thickness (t). The honeycomb structural body (10) satisfies particular relationships between the partition wall thickness (t) and the open frontal area (OFA) or bulk density (G). Notwithstanding the thin-walled partition walls, the honeycomb structural body (10) has practically satisfactory compressive strength characteristics. The catalyst comprising the honeycomb structural body (10) has reduced pressure loss and heat capacity.

Abstract: A curved honeycomb structural body having a number of through holes extending through the structural body along a direction in which the honeycomb structural body is curved. Thicknesses of interior walls defining through holes are set larger on a radially outer side of the curved portion than on a radially inner side thereof.