Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.

Abstract: An electrophotographic roller comprising a substrate comprising a conductive outer surface and a resin layer on the outer surface of the substrate, wherein the resin layer comprises a polyurethane having a polycarbonate structure, an impedance at a frequency of 1.0×100 to 1.0×101 Hz is 1.00×106? or more when a specific AC voltage is applied to the outer surface of the electrophotographic roller while a frequency is changed between specific range, and when a corona discharger having a grid part is moved along an axial direction of the electrophotographic roller at a speed of 400 mm/sec, a maximum value of an electric potential of the outer surface is less than 20.0 V when measured at 0.06 seconds after a passage of the grid part.

Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. Provided is a compound of formula (I): wherein each symbol is as described in the specification, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.

Abstract: Provided is a method for manufacturing a laminated core capable of reducing the likelihood that the iron loss increases while increasing the space factor of the laminated core. A method for manufacturing a laminated core includes a laminating step of laminating a plurality of thin plates made of a soft magnetic material, an impregnating step of filling a resin into spaces between the plurality of thin plates laminated, and a fixing step of curing the filled resin to fix the plurality of thin plates laminated. In the fixing step, the resin is cured while applying a pressure larger than 0 MPa and equal to or smaller than 1.5 MPa to the plurality of thin plates laminated in a laminating direction of the plurality of thin plates.

Abstract: The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the prophylaxis or treatment of Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies, and the like. The present invention relates to a compound represented by the formula (I) or a salt thereof. wherein each symbol is as described in the specification, or a salt thereof.

Abstract: An object monitoring system includes means for determining an arrangement relationship between a monitoring area and an external object on a basis of a distance measurement value of the external object, and calculating an influence degree of the external object on an object distance measurement in the monitoring area in accordance with the determined arrangement relationship.

Abstract: A compound of formula (I), or a salt thereof that may have an antagonistic action against an NMDA receptor that includes an NR2B subunit and may be useful as a prophylactic or therapeutic agent for depression, bipolar disorder, migraine, pain, a symptom peripheral to dementia, or the like.

Abstract: Abstract: The present invention refers to compounds of formula (I). The present invention also relates to compounds of formula (I) for use as G Protein coupled Receptor 139 (GPR139) antagonists in methods of medical treatment of e.g. depression, Alzheimer’s disease, schizophrenia, drug addiction, sleep disorders, pain, and attention deficit hyperactivity disorder. Exemplary compounds are e.g. 3-((1H-pyrazol-4-yl)methyl)-6?-(phenyl)-2H-(1,2?-bipyridin)-2-one derivatives and related compounds. The present description discloses the synthesis and characterisation of exemplary compounds, pharmacological data thereof, as well as exemplary tablet formulations comprising the compounds of the invention (e.g. page 83 to page 110; examples 1 to 33; reference example 1; test examples 1 and 2; tables 1 to 4).

Abstract: The present invention refers to compounds of formula (I). The present invention also relates to compounds of formula (I) for use as G Protein coupled Receptor 139 (GPR139) antagonists in methods of medical treatment of e.g. depression, Alzheimer's disease schizophrenia, drug addiction, sleep disorders, pain, and attention deficit hyperactivity disorder. Exemplary compounds are e.g. 1-(OH-pyrazol-4-yl)methyl)-3-(phenyl)-1,3-dihydro-2H-imidazol-2-one derivatives and related compounds. The present description discloses the synthesis and characterisation of exemplary compounds, pharmacological data thereof, as well as exemplary tablet formulations comprising the compounds of the invention (e.g. page 100 to page 143; examples 1 to 167; test examples 1 and 2; tables 1 to 4).

Abstract: A distance measurement device includes a light emission unit which is capable of emitting measurement light to be irradiated toward an object, a light reception unit configured to receive light from the object via an optical filter through which light having the same wavelength band as the measurement light passes, a distance calculation unit configured to calculate a distance to the object based on each charge amount obtained by accumulating a charge corresponding to the received light at a plurality of timings which are delayed by a predetermined phase with respect to emission timing of the measurement light, and an external light intensity calculation unit configured to calculate external light illuminance of external light illuminating the object at the spectral sensitivity of the optical filter based on the charge amounts acquired at the light reception unit and a reflectivity of the object.

Abstract: A distance-measuring apparatus includes an optical window incorporating a first polarizing filter that polarizes reference light and a second polarizing filter that polarizes incident light in a direction inclined at 90 degrees relative to a polarization direction of the first polarizing filter.

Abstract: The present invention provides a heterocyclic compound having an antagonistic action on an NMDA receptor containing the NR2B subunit, and expected to be useful as an agent for the prophylaxis or treatment of major depression, bipolar disorder, migraine, pain, behavioral and psychological symptoms of dementia and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the description, or a salt thereof.

Abstract: A distance-measuring apparatus includes a precision calculation section that calculates a precision for each pixel, the precision based on a relation among the amounts of the electric charges stored at a plurality of timings that respectively delay by certain phases from a timing of the emission of the measuring light, wherein the precision is outputted from the distance-measuring apparatus.

Abstract: A compound of formula (I), or a salt thereof that may have an antagonistic action against an NMDA receptor that includes an NR2B subunit and may be useful as a prophylactic or therapeutic agent for depression, bipolar disorder, migraine, pain, a symptom peripheral to dementia, or the like.

Abstract: Provided is a developing device including: a toner; and a developer carrying member. The developer carrying member includes an electroconductive substrate and a surface layer on the substrate, the surface layer being a single layer and including a matrix containing a crosslinked urethane resin as a binder, wherein E1 ?200 MPa and 10 MPa?E2 ?100 MPa, where E1 is an elastic modulus of the matrix in a first region from an outer surface of the surface layer to a depth of 0.1 and E2 is an elastic modulus of the matrix in a second region from a depth of 1.0 to 1.1 ?m from the outer surface. The toner includes a toner particle containing a binder resin and a colorant and having a Martens hardness of 85 to 1,100 MPa when measured under a condition of a maximum load of 2.0×10?4 N.

Abstract: A compound of formula (I), or a salt thereof that may have an antagonistic action against an NMDA receptor that includes an NR2B subunit and may be useful as a prophylactic or therapeutic agent for depression, bipolar disorder, migraine, pain, a symptom peripheral to dementia, or the like.

Abstract: A distance image capturing system including: an image acquisition unit for capturing a plurality of images of an object at the same image capturing position and in the same image capturing orientation with respect to the object to acquire a plurality of first distance images; an image synthesis unit for synthesizing the plurality of first distance images to generate a second distance image; and a number-of-image-capturing-operation determination unit for estimating a distance measurement error in the second distance image and determining the number of image capturing operations for the first distance images at which the estimated distance measurement error is equal to or less than a predetermined target error.

Abstract: A three-dimensional measurement device includes a camera for acquiring position information for three-dimensional points on the surface of an object on the basis of the time of flight of light, and a control device. The camera acquires, at a plurality of relative positions of the camera with respect to a workpiece, three-dimensional point position information. A plurality of evaluation regions are defined for the workpiece. The control device specifies, for each evaluation region, the three-dimensional point closest to a reference plane from among three-dimensional points detected in the evaluation region. The control device generates, on the basis of the multiple three-dimensional points specified for the respective evaluation regions, three-dimensional point position information in which multiple pieces of three-dimensional point position information acquired by the camera are combined.

Abstract: An object monitoring system includes a distance measuring device which generates, while repeating an imaging cycle having different imaging modes, a distance image of a target space for each of the imaging modes, and a computing device which determines presence or absence of an object within a monitoring area set in the target space based on the distance image.

Abstract: A compound of formula (I), or a salt thereof that may have an antagonistic action against an NMDA receptor that includes an NR2B subunit and may be useful as a prophylactic or therapeutic agent for depression, bipolar disorder, migraine, pain, a symptom peripheral to dementia, or the like.