Abstract: A high-performance and flexible loudspeaker apparatus usable in various scenes. A first unit includes a loudspeaker therein, a second unit is connected to a lower portion of the first unit, the first unit comprises the loudspeaker provided in a housing of the first unit so as to output a sound toward an upper portion of the housing and a passive radiator provided on a rear surface side of the loudspeaker in the housing, and an output port of the passive radiator is opposed to an inclined surface which is provided at an upper portion of the second unit and whose distance from the output port of the passive radiator increases toward a radially outer side of the housing.

Abstract: A medical retrieval instrument of the present invention includes a plurality of filaments for holding an object and a hollow section through which a first end of each of said plurality of filaments passes. The hollow section comprises a plurality of fixing sections for fixing a second end of each of said plurality of filaments, for example. The hollow section is arranged in a distal end portion of a sheath. The hollow section is inserted into the body cavity by the sheath and then holds an object such as renal calculus or ureteral calculus in the body cavity and retrieves them to outside the body.

Abstract: A medical retrieval instrument of the present invention includes a plurality of filaments for holding an object and a hollow section through which a first end of each of said plurality of filaments passes. The hollow section comprises a plurality of fixing sections for fixing a second end of each of said plurality of filaments, for example. The hollow section is arranged in a distal end portion of a sheath. The hollow section is inserted into the body cavity by the sheath and then holds an object such as renal calculus or ureteral calculus in the body cavity and retrieves them to outside the body.

Abstract: The treatment tool for an endoscope has an operation portion including an operation portion body and a slider. The operation portion body has a proximal end portion provided with a ring-like finger engaging portion, and a grip portion is formed to be adjacent to the finger engaging portion. The slider has a pair of flanges for engaging a finger and a finger rest extending from the flange adjacent the rear end portion. An operator can insert his or her thumb of one hand into the ring-like finger engaging portion, and engages another finger of the same hand between the pair of flanges of the slider. The operation portion body and the slider can be relatively moved thereby. Otherwise, the operator can also relatively move the operation portion body and the slider by gripping the grip portion of the operation portion body on his or her palm of one hand and by engaging the thumb of the same hand on the finger rest of the slider shaped like a hood.

Abstract: A medical treatment instrument is provided with a treatment section for treating issue, an insertion section which has at one end the treatment section, and an operating section which is provided at the other end of the insertion section, operates the treatment section, and has a fixed portion and a movable portion. The treatment section is actuated by pivoting the movable portion with respect to the fixed portion. The medical treatment instrument is further provided with an actuating main body and a cover. The cover is displaceable between a first position in which the medical treatment instrument is used and a second position in which the inside of the operating section is uncovered.

Abstract: The present invention relates to a method for controlling carbon source concentration in the aerobic cultivation of a microorganism. The substrate carbon source remains at a low level in a cultivation vessel during the culture feeding in aerobic fed-batch, continuous or cell-recycling continuous cultures. This is accomplished by monitoring the increase in pH or dissolved oxygen content in the culture medium and adding the feed solution intermittently into a cultivation vessel at a calculated feed rate using a feed control device controlled by a computer.The present invention further relates to a process for producing L-lysine by fermentation having the advantages over the prior methods, those being improved productivity, higher concentrations of accumulated product, and increased yields of L-lysine.

Abstract: The present invention is a method for aerobically cultivating yeast or bacteria in a culture medium of fed-batch, continuous or cell-recycling continuous cultures, wherein the carbon source concentration in the culture medium is maintained at a constant low level of under g/l. The carbon source concentration is maintained by measuring the carbon consumption of a culture of the yeast or bacteria in a preliminary experiment. The rate is determined between the time the culture is started and a time when the carbon source is exhausted. A feeding time is then determined wherein the activity of the yeast or bacteria in the presence of the carbon source does not change and a volume of the carbon source to be used in a first feeding (So) is set as So=.nu..times.T. Then, in a main culture, a first feeding of a volume of the carbon source (So) is added for the time (T), and the exhaustion of the carbon source is detected as an increase in pH or an increase in concentration of oxygen dissolved in the culture medium.

Abstract: A surgical instrument for fastening together opposing portions of a body organ. The instrument comprises a first support for supporting the first opposing portion of the body organ, a second support opposing the first support, for supporting the second opposing portion of the body organ, and a displacement-preventing member connected to the first or second support for preventing the supports from displacing relative to each other. The member comprises a pin protruding from one of the supports and a hole formed in the other of the supports. The pin is made of thermoplastic resin. When heated, the pin is softened and deformed, whereby the first and second supports are secured to each other, fastening together the opposing portions of the body organ.

Abstract: A surgical instrument for fastening together opposing portions of a body organ. The instrument comprises a first support for supporting the first opposing portion of the body organ, a second support opposing the first support, for supporting the second opposing portion of the body organ, and a displacement-preventing member connected to the first or second support for preventing the supports from displacing relative to each other. The member comprises a pin protruding from one of the supports and a hole formed in the other of the supports. The pin is made of thermoplastic resin. When heated, the pin is softened and deformed, whereby the first and second supports are secured to each other, fastening together the opposing portions of the body organ.

Abstract: A disc drive for use with a disc-shaped recording medium, includes a disc driving mechanism for driving the recording medium mounted on a disc mounting surface thereof and a clamping mechanism for clamping the recording medium on the disc mounting surface of the disc drive mechanism. A further driving mechanism is provided for moving the clamping mechanism into a clamping position in which it clamps the recording medium on the disc mounting surface and maintains the clamping mechanism in the clamping position. A motor drives the further driving mechanism. A manually operated mechanism releases transmission between the further driving mechanism and the motor, and manually operates the further driving mechanism to eject the recording medium out of the disc drive.

Abstract: A surgical instrument for fastening together opposing portions of a body organ. The instrument comprises a first support for supporting the first opposing portion of the body organ, a second support opposing the first support, for supporting the second opposing portion of the body organ, and a displacement-preventing member connected to the first or second support for preventing the supports from displacing relative to each other. The member comprises a pin protruding from one of the supports and a hole formed in the other of the supports. The pin is made of thermoplastic resin. When heated, the pins is softened and deformed, whereby the first and second supports are secured to each other, fastening together the opposing portions of the body organ.

Abstract: A surgical instrument for fastening together opposing portions of a body organ. The instrument comprises a first support for supporting the first opposing portion of the body organ, a second support opposing the first support, for supporting the second opposing portion of the body organ, and a displacement-preventing member connected to the first or second support for preventing the supports from displacing relative to each other. The member comprises a pin protruding from one of the supports and a hole formed in the other of the supports. The pin is made of thermoplastic resin. When heated, the pins is softened and deformed, whereby the first and second supports are secured to each other, fastening together the opposing portions of the body organ.

Abstract: A medical instrument performs at least one of suture and ligation to form a suitable knot in a piece of suture within a body cavity. This medical instrument includes a suture having a first end portion, a second end portion, and at least one loop formed in advance at an intermediate portion between the first and second end portions to have a predetermined size, and a suture suitable for application to a body tissue, and a cylindrical body for holding the loop to almost maintain the size thereof. The body has a fastening portion for fastening at least one portion of the suture. The medical instrument further includes an inserting instrument which is to be inserted into the body cavity, which has a distal end portion that can be arranged in the body cavity, and an operating portion, arranged outside the body, for operating the distal end portion thereof, and on which a holding member having the suture wound thereon is mounted.

Abstract: A surgical device for stapling and fastening body tissues, comprises an insertion section extending from an operation section for insertion into a body cavity, stapling member connected to a distal end of the insertion section, for treating body tissues with a high-frequency current within a body cavity. The stapling member includes an anvil and a cartridge between which the tissues are sandwiched, and a cutter. Staples are applied to the anvil from the cartridge for stapling the tissues and the cutter cuts the tissue while it applies a high-frequency current thereto.

Abstract: Disclosed herein is a surgical device for applying surgical fasteners to body tissues in order to fasten the body tissues together. The device comprises an operation section having a housing having an inner space completely sealed from the outside, drive elements electrically driven and arranged in the inner space of the operation section, an insertion section including a housing which has a first end portion containing the fasteners and having an opening through which the fasteners are to be applied, and a second end portion removably coupled to the housing of the operation section, fastener-applying elements located in the housing of the insertion section, for applying the fasteners from the opening to body tissues, and force-transmitting elements for transmitting drive force from the drive elements to the fastener-applying elements.

Abstract: A trocar comprises an obturator having a piercing tip, and a cannula for forming a passage in tissue that is punched by the piercing tip. The cannula is formed from a flexible tube or a coil tube and transforms and libitum in accordance with the shape of the surgical tool that is to be inserted into the body cavity through the cannula. Therefore, the trocar of the invention allows insertion of a surgical tool curved in a circular arc into the body cavity without requiring no enlargement of the inside diameter of the cannula.

Abstract: A surgical device for stapling and fastening body tissues, which comprises a staple-applying section containing a plurality of staples, a staple pusher incorporated in the staple-applying section, for applying the staples, an anvil section for deforming the staples, thereby to staple the body tissues together, an operation section for operating the staple pusher and the anvil section, an observation window located near the anvil section, and an ocular section for displaying images supplied from the observation window.

Abstract: A surgical device for stapling and fastening body tissues, comprises an insertion section extending from an operation section for insertion into a body cavity, stapling member connected to a distal end of the insertion section, for treating body tissues with a high-frequency current within a body cavity. The stapling member includes an anvil and a cartridge between which the tissues are sandwiched, and a cutter. Staples are applied to the anvil from the cartridge for stapling the tissues and the cutter cuts the tissue while it applies a high-frequency current thereto.

Abstract: Amino acid fermentation is conducted by fermenting bacterial cells in a culture medium in a fermentor and separating fermentation solution withdrawn from the fermentor into a solution containing said bacterial cells and a solution not containing bacterial cells by a cell separator. The solution containing said bacterial cells being circulated from said cell separator to said fermenter by circulating means to perform amino acid fermentation continuously, and bubbles being removed from said fermentation solution by a bubble separator before said fermentation solution is fed to said circulating means and said cell separator.