Patents by Inventor Minrui Yu

Minrui Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Laser drilling technique for creating nanoscale holes
    Patent number: 8623496
    Abstract: A method of forming extremely small pores in a substrate that is used, for example, in patch clamp applications is provided that employs an energy absorbing material beyond a back side of the substrate to allow a laser to be focused adjacent the exit side of the substrate so as to generate a pore through the substrate and can also form a crater in the back side of the substrate and in which the pore may propagate from the crater in a drilling direction that can oppose a laser transmission direction.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: January 7, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Robert H. Blick, Minrui Yu
  • PIEZOELECTRIC SUBSTRATE FOR THE STUDY OF BIOMOLECULES
    Publication number: 20130249530
    Abstract: A method of forming extremely small pores in a substrate may be used to produce, for example, an apparatus for the study of biological molecules, by providing a small pore in a piezoelectric substrate having electrodes, the latter that may be energized to change the pore dimensions.
    Type: Application
    Filed: May 14, 2013
    Publication date: September 26, 2013
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Robert H. Blick, Minrui Yu
  • Retro-Percussive Technique for Creating Nanoscale Holes
    Publication number: 20120141729
    Abstract: A method of forming extremely small pores in glass or a similar substrate, useful, for example, in patch clamp applications, that employs a backer plate to contain energy of a laser-induced ablation through the front surface of the substrate so as to create a rear surface shock wave providing a fire polishing of the exit aperture of the pore such as produces improved sealing with cell membranes.
    Type: Application
    Filed: December 2, 2011
    Publication date: June 7, 2012
    Inventors: Robert H. Blick, Minrui Yu, Hua Qin, Hyun-Seok Kim
  • TUBULAR SCAFFOLD FOR NEURAL GROWTH
    Publication number: 20120064628
    Abstract: A scaffold for neurons consists of tubes sized to promote neural growth through the tubes. The tubes may be fixed to a substrate providing electrical or optical paths out from the interior of the tubes from sensors or stimulating probes at one or more locations along the length of the coaxial axons. Steering electrodes at spaces between tubes may be used to selectively promote the growth of interconnections of different axons in a one, two, or three-dimensional fashion.
    Type: Application
    Filed: September 13, 2010
    Publication date: March 15, 2012
    Inventors: Robert H. Blick, Justin Williams, Minrui Yu, Yu Huang
  • Retro-percussive technique for creating nanoscale holes
    Patent number: 8092739
    Abstract: A method of forming extremely small pores in glass or a similar substrate, useful, for example, in patch clamp applications, that employs a backer plate to contain energy of a laser-induced ablation through the front surface of the substrate so as to create a rear surface shock wave providing a fire polishing of the exit aperture of the pore such as produces improved sealing with cell membranes.
    Type: Grant
    Filed: November 25, 2008
    Date of Patent: January 10, 2012
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Robert H. Blick, Minrui Yu, Hua Qin, Hyun-Seok Kim
  • LASER DRILLING TECHNIQUE FOR CREATING NANOSCALE HOLES
    Publication number: 20110111179
    Abstract: A method of forming extremely small pores in a substrate that is used, for example, in patch clamp applications is provided that employs an energy absorbing material beyond a back side of the substrate to allow a laser to be focused adjacent the exit side of the substrate so as to generate a pore through the substrate and can also form a crater in the back side of the substrate and in which the pore may propagate from the crater in a drilling direction that can oppose a laser transmission direction.
    Type: Application
    Filed: November 6, 2009
    Publication date: May 12, 2011
    Inventors: Robert H. Blick, Minrui Yu
  • RETRO-PERCUSSIVE TECHNIQUE FOR CREATING NANOSCALE HOLES
    Publication number: 20100129603
    Abstract: A method of forming extremely small pores in glass or a similar substrate, useful, for example, in patch clamp applications, that employs a backer plate to contain energy of a laser-induced ablation through the front surface of the substrate so as to create a rear surface shock wave providing a fire polishing of the exit aperture of the pore such as produces improved sealing with cell membranes.
    Type: Application
    Filed: November 25, 2008
    Publication date: May 27, 2010
    Inventors: Robert H. Blick, Minrui Yu, Hua Qin, Hyun-Seok Kim