Patents by Inventor Miquel A. Ondetti

Miquel A. Ondetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mercaptoacyldepeptides
    Patent number: 4684660
    Abstract: Compounds having the formula ##STR1## and alkyl esters and salts thereof. R.sub.1 is hydrogen, alkanoyl or ##STR2## R.sub.2 is hydrogen, alkyl, or phenylalkyl; n is 0 or 1; andA.sub.1 and A.sub.2 each is an .alpha.-amino or .alpha.-imino acid residue joined through a peptide bond, have useful hypotensive activity.
    Type: Grant
    Filed: May 1, 1980
    Date of Patent: August 4, 1987
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Miquel A. Ondetti, Josip Pluscec
  • Dithio aminoacid derivatives
    Patent number: 4173704
    Abstract: A method for alleviating or reducing angiotensin related hypertension in hypertensive mammals comprises administering to such hypertensive mammals an effective amount of an angiotensin converting enzyme inhibitor selected from a group of mercaptoacyl aminoacids.
    Type: Grant
    Filed: May 26, 1978
    Date of Patent: November 6, 1979
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Miquel A. Ondetti, David W. Cushman