Patents by Inventor Mira Josowicz

Mira Josowicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100276734
    Abstract: Electrochemical biosensor arrays and systems, as well as methods of making the electrochemical biosensor arrays and systems, are described herein. The electrochemical biosensor systems can be used with CMOS detection circuits that have a plurality of chemical detection and/or actuation channels or sites. The biosensor systems generally include a first inert conducting electrode disposed on a first portion of a CMOS detection circuit and a polymeric layer adjacent the first inert conducting electrode. The biosensor systems can also include a capture biomolecule bound to the polymeric layer. The biosensor system can also include the CMOS detection and/or actuation circuit having a plurality of channels.
    Type: Application
    Filed: August 14, 2007
    Publication date: November 4, 2010
    Applicants: Georgia Tech Research Corporation, Eidgenössische Technische Hochschule Zürich
    Inventors: Mira Josowicz, Jiri Janata, Janusz Kowalik, Andreas Hierlemann, Flavio Heer, Kay-Uwe Kirstein
  • Patent number: 5569736
    Abstract: The invention is a composition of an inorganic-organic polymer composite and a method of making it. The inorganic portion of the fundamental polymer composite polymer repeat is a speciated inorganic heterocyclic compound, and the organic portion of the polymer repeat is a cyclic organic radical anion compound having at least two charged sites. The composition of the present invention is made by combining a cyclic organic radical anion compound with a speciated inorganic heterocyclic compound by a nucleophilic substitution thereby forming a polymer of an inorganic-organic composite. The cyclic organic radical anion compound is preferably generated electrochemically. The nucleophilic substitution is alternately carried out chemically or electrochemically. A preferred embodiment of the present invention includes performing the nucleophilic substitution at the cathode of an electrochemical cell.
    Type: Grant
    Filed: November 22, 1994
    Date of Patent: October 29, 1996
    Assignee: Battelle Memorial Institute
    Inventors: Mira A. Josowicz, Gregory J. Exarhos
  • Patent number: 5254223
    Abstract: The process for preparation of semipermeable polymer layers with ion-exchanging and ion-conducting capabilities comprises the steps of making and depositing a polymer layer in situ by electrochemical polymerization on an electrically conductive substrate and subsequently cross-linking, by heating or irradiating. The electrochemically formed polymer layers are built up of poly(oxyphenylene) or poly(naphthylene) chains, in which the aromatic units contain the ion-exchanging and ion-conducting groups. These polymer layers are suitable for use as a semipermeable membrane in an electrode/membrane unit, as a selective layer or as a component of a selective layer of potentiometric and amperometric sensors and as a solid polymer electrolyte in electrochemical cells.
    Type: Grant
    Filed: August 21, 1992
    Date of Patent: October 19, 1993
    Inventors: Mira Josowicz, Karin Potje-Kamloth
  • Patent number: 5022969
    Abstract: The process for encasing an electrically conductive region in an electronic component in an insulating layer comprises the steps of depositing a polymer layer by electrochemical polymerization of phenol-, thiophenol- and analine-containing monomers and their combinations from an electrolytic solution on the electrically conductive region and subsequently cross-linking the polymer layer to form a chemically inert insulating layer. The process provides a uniformly adhering thin insulating layer. A field effect transistor so encased is suitable for use as a physical and/or chemical sensor.
    Type: Grant
    Filed: May 15, 1989
    Date of Patent: June 11, 1991
    Inventors: Mira Josowicz, Karin Potje-Kamloth
  • Patent number: 4959130
    Abstract: The ultramicroelectrode comprises a wire or filament of noble metal and/or carbon on which an insulating layer is provided. The insulating layer is made from a cross-linked alkenyl-substituted poly(1,4-phenylene) ether, poly(1,4-phenylene) thioether or poly(1,4-aniline). This ultramicroelectrode can be used as a disk, cylindrical, bipolar or shielded electrode and may be used as a stimulating electrode, amperometric or potentiometric microsensor or as an electrode for analytical measurement, e.g. for inverse voltammetry.
    Type: Grant
    Filed: May 15, 1989
    Date of Patent: September 25, 1990
    Inventors: Mira Josowicz, Karin Potje-Kamloth