Patents by Inventor Mira Sibai

Mira Sibai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Device and method for determining the depth of a subsurface fluorescent object within an optically absorbing and scattering medium and for determining concentration of fluorophore of the object
    Patent number: 11977027
    Abstract: A method and device for determining the depth and fluorophore concentration of a fluorophore concentration below the surface of an optically absorbing and scattering medium suitable for use in fluorescence-based surgical guidance such as in tumor resection is described. Long-wavelength stimulus light us used to obtain deep tissue penetration. Recovery of depth is performed by fitting measured modulation amplitudes for each spatial frequency to precomputed modulation amplitudes in a table of modulation amplitudes indexed by optical parameters and depth.
    Type: Grant
    Filed: May 26, 2023
    Date of Patent: May 7, 2024
    Assignees: UNIVERSITY HEALTH NETWORK
    Inventors: Keith D. Paulsen, David W. Roberts, Dennis Wirth, Brian C. Wilson, Mira Sibai
  • DEVICE AND METHOD FOR DETERMINING THE DEPTH OF A SUBSURFACE FLUORESCENT OBJECT WITHIN AN OPTICALLY ABSORBING AND SCATTERING MEDIUM AND FOR DETERMINING CONCENTRATION OF FLUOROPHORE OF THE OBJECT
    Publication number: 20230324301
    Abstract: A method and device for determining the depth and fluorophore concentration of a fluorophore concentration below the surface of an optically absorbing and scattering medium suitable for use in fluorescence-based surgical guidance such as in tumor resection is described. Long-wavelength stimulus light us used to obtain deep tissue penetration. Recovery of depth is performed by fitting measured modulation amplitudes for each spatial frequency to precomputed modulation amplitudes in a table of modulation amplitudes indexed by optical parameters and depth.
    Type: Application
    Filed: May 26, 2023
    Publication date: October 12, 2023
    Inventors: Keith D. Paulsen, David W. Roberts, Dennis Wirth, Brian C. Wilson, Mira Sibai
  • Device and method for determining depth and concentration of a subsurface fluorescent object
    Patent number: 11662315
    Abstract: A method and device for determining the depth and fluorophore concentration of a fluorophore concentration below the surface of an optically absorbing and scattering medium suitable for use in fluorescence-based surgical guidance such as in tumor resection is described. Long-wavelength stimulus light us used to obtain deep tissue penetration. Recovery of depth is performed by fitting measured modulation amplitudes for each spatial frequency to precomputed modulation amplitudes in a table of modulation amplitudes indexed by optical parameters and depth.
    Type: Grant
    Filed: November 1, 2021
    Date of Patent: May 30, 2023
    Assignees: THE TRUSTEES OF DARTMOUTH COLLEGE, UNIVERSITY HEALTH NETWORK
    Inventors: Keith D. Paulsen, David W. Roberts, Dennis Wirth, Brian C. Wilson, Mira Sibai
  • DEVICE AND METHOD FOR DETERMINING DEPTH AND CONCENTRATION OF A SUBSURFACE FLUORESCENT OBJECT
    Publication number: 20220057328
    Abstract: A method and device for determining the depth and fluorophore concentration of a fluorophore concentration below the surface of an optically absorbing and scattering medium suitable for use in fluorescence-based surgical guidance such as in tumor resection is described. Long-wavelength stimulus light us used to obtain deep tissue penetration. Recovery of depth is performed by fitting measured modulation amplitudes for each spatial frequency to precomputed modulation amplitudes in a table of modulation amplitudes indexed by optical parameters and depth.
    Type: Application
    Filed: November 1, 2021
    Publication date: February 24, 2022
    Inventors: Keith D. Paulsen, David W. Roberts, Dennis Wirth, Brian C. Wilson, Mira Sibai
  • Device and method for determining depth and concentration of a subsurface fluorescent object
    Patent number: 11162900
    Abstract: A method and device for determining the depth and fluorophore concentration of a fluorophore concentration below the surface of an optically absorbing and scattering medium suitable for use in fluorescence-based surgical guidance such as in tumor resection is described. Long-wavelength stimulus light us used to obtain deep tissue penetration. Recovery of depth is performed by fitting measured modulation amplitudes for each spatial frequency to precomputed modulation amplitudes in a table of modulation amplitudes indexed by optical parameters and depth.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: November 2, 2021
    Assignees: THE TRUSTEES OF DARTMOUTH COLLEGE, UNIVERSITY HEALTH NETWORK
    Inventors: Keith D. Paulsen, David W. Roberts, Dennis Wirth, Brian C. Wilson, Mira Sibai
  • DEVICE AND METHOD FOR DETERMINING DEPTH AND CONCENTRATION OF A SUBSURFACE FLUORESCENT OBJECT
    Publication number: 20210239617
    Abstract: A method and device for determining the depth and fluorophore concentration of a fluorophore concentration below the surface of an optically absorbing and scattering medium suitable for use in fluorescence-based surgical guidance such as in tumor resection is described. Long-wavelength stimulus light us used to obtain deep tissue penetration. Recovery of depth is performed by fitting measured modulation amplitudes for each spatial frequency to precomputed modulation amplitudes in a table of modulation amplitudes indexed by optical parameters and depth.
    Type: Application
    Filed: April 26, 2019
    Publication date: August 5, 2021
    Inventors: Keith D. Paulsen, David W. Roberts, Dennis Wirth, Brian C. Wilson, Mira Sibai