Patents by Inventor Miranda Debora Van De Rhee

Miranda Debora Van De Rhee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression-linked gene discovery
    Patent number: 9695469
    Abstract: The invention relates to a method for analyzing a genomic region of an organism, comprising four major parts. The first part involves the isolation of mRNA from a selected organism that is used for the preparation of small single stranded DNA fragments with one adaptor containing an affinity label. These DNA fragments are used in part three. In the second part, genomic DNA from the same or a related organism is isolated. This genomic DNA is fragmented and ligated to adaptor molecules. In the third part, these genomic fragments are hybridized with single stranded DNA fragments from part one, and the hybrids formed in this process are used for synthesis of DNA fragments. These fragments will be used in part four which involves sequencing of these fragments using one of the available high throughput sequencing methods.
    Type: Grant
    Filed: March 17, 2009
    Date of Patent: July 4, 2017
    Assignee: STICHTING GENETWISTER IP
    Inventors: Anne Douwe De Boer, Michaël Johannes Marcus Ebskamp, Simon Albertus Langeveld, Ivo Laros, Miranda Debora Van De Rhee
  • EXPRESSION-LINKED GENE DISCOVERY
    Publication number: 20110105338
    Abstract: The invention relates to a method for analyzing a genomic region of an organism, comprising four major parts. The first part involves the isolation of mRNA from a selected organism that is used for the preparation of small single stranded DNA fragments with one adaptor containing an affinity label. These DNA fragments are used in part three. In the second part, genomic DNA from the same or a related organism is isolated. This genomic DNA is fragmented and ligated to adaptor molecules. In the third part, these genomic fragments are hybridized with single stranded DNA fragments from part one, and the hybrids formed in this process are used for synthesis of DNA fragments. These fragments will be used in part four which involves sequencing of these fragments using one of the available high throughput sequencing methods.
    Type: Application
    Filed: March 17, 2009
    Publication date: May 5, 2011
    Applicant: EXPRESSIVE RESEARCH B.V.
    Inventors: Anne Douwe De Boer, Michaél Johannes Marcus Ebskamp, Simon Albertus Langeveld, Ivo Laros, Miranda Debora Van De Rhee