Abstract: A drug delivery device system with mutable indicia and method for using same are provided. The drug delivery device system includes a syringe and/or syringe components (e.g., needle shield, needle guard), or autoinjector pen, or wearable autoinjector with mutable indicia and a software application for an external device to analyze images of the mutable indicia to automatically determine and record status of the drug delivery device. The mutable indicia or codes on the drug delivery device or its components represent different medical events such as dose completion, dose amount, and safety feature deployment or removal and can be detected by and otherwise logged by the external device. The external device may execute an application configured to further process data obtained via captured images of mutable indicia and display related information (e.g., fluid remaining in syringe barrel, delivered dose, and so on).

Abstract: An extremely high efficiency, cross flow, fluid-fluid, micro heat exchanger and novel method of fabrication using electrode-less deposition is disclosed. To concurrently achieve the goals of high mass flow rate, low pressure drop, and high heat transfer rates, the heat exchanger comprises numerous parallel, but relatively short microchannels. Typical channel heights are from a few hundred micrometers to about 2000 micrometers, and typical channel widths are from around 50 micrometers to a few hundred micrometers. The micro heat exchangers offer substantial advantages over conventional, larger heat exchangers in performance, weight, size, and cost. The heat exchangers are especially useful for enhancing gas-side heat exchange. The use of microchannels in a cross-flow micro-heat exchanger decreases the thermal diffusion lengths substantially, allowing substantially greater heat transfer per unit volume or per unit mass than has been achieved with prior heat exchangers.

Abstract: An extremely high efficiency, cross flow, fluid-fluid, micro heat exchanger and novel method of fabrication using electrode-less deposition is disclosed. To concurrently achieve the goals of high mass flow rate, low pressure drop, and high heat transfer rates, the heat exchanger comprises numerous parallel, but relatively short microchannels. Typical channel heights are from a few hundred micrometers to about 2000 micrometers, and typical channel widths are from around 50 micrometers to a few hundred micrometers. The micro heat exchangers offer substantial advantages over conventional, larger heat exchangers in performance, weight, size, and cost. The heat exchangers are especially useful for enhancing gas-side heat exchange. The use of microchannels in a cross-flow micro-heat exchanger decreases the thermal diffusion lengths substantially, allowing substantially greater heat transfer per unit volume or per unit mass than has been achieved with prior heat exchangers.

Abstract: An extremely high efficiency, crossflow, fluid-fluid, micro heat exchanger is disclosed. To concurrently achieve the goals of high mass flow rate, low pressure drop, and high heat transfer rates, the heat exchanger comprises numerous parallel, but relatively short microchannels. The performance of these heat exchangers is superior to the performance of previously available heat exchangers. Typical channel heights are from a few hundred micrometers to about 2000 micrometers, and typical channel widths are from around 50 micrometers to a few hundred micrometers. The micro heat exchangers offer substantial advantages over conventional, larger heat exchangers in performance, weight, size, and cost. The heat exchangers are especially useful for enhancing gas-side heat exchange. Some of the many possible applications include aircraft heat exchange, air conditioning, portable cooling systems, and micro combustion chambers for fuel cells.