Patents by Inventor Mirco Ponzoni

Mirco Ponzoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipid vectors delivering gene silencers
    Publication number: 20130202687
    Abstract: Lipid vector delivering gene silencers which vector carries on its external surface at least one recognizing molecule directed against a cellular target molecule. The recognizing molecule is directed against GD2 disialoganglioside epitope, a tumor-associated membrane antigen expressed abundantly by neuroectodermal tumor cells, and which lipid vector contains as therapeutic agent double-stranded RNA synthetic oligonucleotides such as siRNAs (small interfering RNAs), complementary to mRNAs (messenger RNAs) coding for at least one oncogene such to obtain silencing, that is the selectively decreased expression of the oncogene, in target cells.
    Type: Application
    Filed: October 14, 2011
    Publication date: August 8, 2013
    Applicant: ISTITUTO GIANNINA GASLINI
    Inventors: Patrizia Perri, Gabriella Pagnan, Fabio Pastorino, Mirco Ponzoni
  • METHODS FOR INHIBITING ANGIOGENESIS WITH MULTI-ARM POLYMERIC CONJUGATES OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN
    Publication number: 20120122956
    Abstract: The present invention relates to methods of inhibiting angiogenesis in mammals. The present invention includes administering polymeric prodrugs of 7-ethyl-10-hydroxycamptothecin to the mammals in need thereof. The present invention also relates to methods of treating a disease associated with angiogenesis in mammals by administering polymeric prodrugs of 7-ethyl-10-hydroxycamptothecin to the mammals in need thereof.
    Type: Application
    Filed: April 15, 2010
    Publication date: May 17, 2012
    Applicant: ENZON PHARMACEUTICALS, INC.
    Inventors: Fabio Pastorino, Mirco Ponzoni, Puja Sapra
  • TREATMENT OF NEUROBLASTOMA WITH MULTI-ARM POLYMERIC CONJUGATES OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN
    Publication number: 20100098654
    Abstract: The present invention relates to methods of treatment of neuroblastoma. The present invention includes administering polymeric prodrugs of 7-ethyl-10-hydroxycamptothecin to patients in need thereof.
    Type: Application
    Filed: October 15, 2009
    Publication date: April 22, 2010
    Inventors: Fabio Pastorino, Mirco Ponzoni
  • Tumor-targeted drug delivery systems and uses thereof
    Publication number: 20090092663
    Abstract: The present invention relates to targeted delivery systems for delivering therapeutic agents to tumor. The invention further relates to methods of delivering a therapeutic agent to a tumor for the prevention and treatment of cancer by killing tumor cells and tumor-associated endothelial cells. In particular, the present invention provides a tumor-targeted drug delivery system comprising a NGR-containing molecule linked to a delivery vehicle encapsulating a therapeutic agent, preferably a drug, such as a cytotoxic agent or a chemotherapeutic agent. Specifically, the delivery systems of the present invention are capable of delivering an increased amount of therapeutic agent to a tumor as compared to other delivery systems.
    Type: Application
    Filed: August 29, 2008
    Publication date: April 9, 2009
    Applicants: G. Gaslini Children's Hospital, Fondazione Centro San Raffaele Del Monte Tabor, The Governors of the University of Alberta
    Inventors: Mirco Ponzoni, Angelo Corti, Theresa M. Allen
  • Tumor-targeted drug delivery systems and uses thereof
    Patent number: 7479483
    Abstract: The present invention relates to targeted delivery systems for delivering therapeutic agents to tumor. The invention further relates to methods of delivering a therapeutic agent to a tumor for the prevention and treatment of cancer by killing tumor cells and tumor-associated endothelial cells. In particular, the present invention provides a tumor-targeted drug delivery system comprising a NGR-containing molecule linked to a delivery vehicle encapsulating a therapeutic agent, preferably a drug, such as a cytotoxic agent or a chemotherapeutic agent. Specifically, the delivery systems of the present invention are capable of delivering an increased amount of therapeutic agent to a tumor as compared to other delivery systems.
    Type: Grant
    Filed: May 26, 2004
    Date of Patent: January 20, 2009
    Assignees: G. Gaslini Children's Hospital, Fondazione Centro San Raffaele del Monte, University of Alberta
    Inventors: Mirco Ponzoni, Angelo Corti, Theresa M. Allen
  • Tumor-targeted drug delivery systems and uses thereof
    Publication number: 20040258747
    Abstract: The present invention relates to targeted delivery systems for delivering therapeutic agents to tumor. The invention further relates to methods of delivering a therapeutic agent to a tumor for the prevention and treatment of cancer by killing tumor cells and tumor-associated endothelial cells. In particular, the present invention provides a tumor-targeted drug delivery system comprising a NGR-containing molecule linked to a delivery vehicle encapsulating a therapeutic agent, preferably a drug, such as a cytotoxic agent or a chemotherapeutic agent. Specifically, the delivery systems of the present invention are capable of delivering an increased amount of therapeutic agent to a tumor as compared to other delivery systems.
    Type: Application
    Filed: May 26, 2004
    Publication date: December 23, 2004
    Inventors: Mirco Ponzoni, Angelo Corti, Theresa M. Allen