Abstract: Disclosed is a new vector for pharmacologically active water-insoluble molecules. These nanovectors, which are in the form of carbon nanoplatforms, are capable of solubilising the active molecules while reducing the side effects of the treatments. Also disclosed are the processes for synthesizing these nanoplatforms, as well as to the use thereof as a drug, particularly in the treatment of brain tumors.

Abstract: The invention relates to compounds of formula (I) wherein the groups A and B represent independently from each other —CH?CH—, or —C?C—, the terms t, u, v, w represent, independently from each other, values ranging from 0 to 9, the groups Y1 and Y2 can represent independently from each other an alkyl group (linear, branched or substituted) carrying from 1 to 9 carbon atoms, the groups Z1, Z2, Z3, and Z4 can represent independently from each other a chemically reactive group W, such as OH, NH2, SH, the groups Z5 and Z6 represent independently from each other a hydrogen atom, silica nanoparticles functionalized by these compounds, and their use as drugs.

Abstract: Fluorescent chemical compound composed of an n-generation dendrimer, n being a non-zero integer, exhibiting: —at least one central nucleus (N) with a valency of m, selected from the group consisting of—at least one first, non-chromophoric unit (X) with a valency of m?, and—at least one second unit (Y) which exhibits two-photon absorption properties, with a valency of m?.

Abstract: The invention relates to compounds of formula (I) wherein the groups A and B represent independently from each other —CH?CH—, or —C?C—, the terms t, u, v, w represent, independently from each other, values ranging from 0 to 9, the groups Y1 and Y2 can represent independently from each other an alkyl group (linear, branched or substituted) carrying from 1 to 9 carbon atoms, the groups Z1, Z2, Z3, and Z4 can represent independently from each other a chemically reactive group W, such as OH, NH2, SH, the groups Z5 and Z6 represent independently from each other a hydrogen atom, silica nanoparticles functionalized by these compounds, and their use as drugs.

Abstract: Fluorescent chemical compound composed of an n-generation dendrimer, n being a non-zero integer, exhibiting: -at least one central nucleus (N) with a valency of m, selected from the group consisting of -at least one first, non-chromophoric unit (X) with a valency of m?, and -at least one second unit (Y) which exhibits two-photon absorption properties, with a valency of m?.

Abstract: Task-specific onium salts, process for preparing them and use thereof for detecting and assaying metals, in particular heavy metals, in an aqueous medium.

Abstract: The invention relates to a chemical compound with an effective double photon absorbance section of greater than 50 GM, preferably greater than 100 GM, for at least one wavelength in the range 700-1200 nm, characterised in being made up of a core with double photon absorption properties connected by separate covalent bonds to at least two boron dipyrromethene type emitters of formula (—BDP) (I): where one of R1 to R7 represents a covalent bond to said core, the others being identical or different each representing a group from H, C1-C25 alkyl, preferably C1-C12, (CH2)m—SO3M, (CH2)mNAlk3+, (CH2)m-(OCH2—CH2)p—OH, where M=an alkaline metal and m=0 or a whole number from 1 to 12 inclusive, preferably between 1 and 6, p=a whole number between 1 and 25 inclusive, aryl, heteroaryl, arylethenyl or arylethynyl.

Abstract: The present invention is directed to various methods involving nonlinear microscopy and dyes that are sensitive to fast cellular membrane potential signals and capable of generating nonlinear optical signals. The present invention includes methods of producing high spatiotemporal resolution images of electrical activity in cellular tissue, as well as methods of detecting and investigating disease within a particular cellular tissue of a living organism. The present invention further relates to methods of detecting membrane potential signal changes in a neuron or a part of a neuron, as well as in a population of cells.