Patents by Inventor Mirela BOCA

Mirela BOCA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and tools for detecting interactions in eukaryotic cells using microtubule structures and dynamics
    Patent number: 10591486
    Abstract: A method for detecting an interaction between one or more protein bait and one or more candidate prey in a eukaryotic cell, comprising the steps of: a) providing an eukaryotic cell expressing (i) one or more protein bait, and (ii) one or more candidate prey, wherein said protein bait comprises a bait moiety and a polymerized-tubulin binding moiety. b) determining the occurence of an interaction between said one or more protein bait and said one or more candidate prey in the eukaryotic cell, wherein said protein bait is bound to polymerized tubulin in the eukaryotic cell, thereby localizing said one or more candidate prey along said polymerized tubulin, thereby detecting said interaction.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: March 17, 2020
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE D'EVRY — VAL D-ESSONNE
    Inventors: David Pastre, Michel Cailleret, Patrick Curmi, Mirela Boca
  • METHODS AND TOOLS FOR DETECTING INTERACTIONS IN EUKARYOTIC CELLS USING MICROTUBULE STRUCTURES AND DYNAMICS
    Publication number: 20170242026
    Abstract: A method for detecting an interaction between one or more protein bait and one or more candidate prey in a eukaryotic cell, comprising the steps of: a) providing an eukaryotic cell expressing (i) one or more protein bait, and (ii) one or more candidate prey, wherein said protein bait comprises a bait moiety and a polymerized-tubulin binding moiety. b) determining the occurence of an interaction between said one or more protein bait and said one or more candidate prey in the eukaryotic cell, wherein said protein bait is bound to polymerized tubulin in the eukaryotic cell, thereby localizing said one or more candidate prey along said polymerized tubulin, thereby detecting said interaction.
    Type: Application
    Filed: July 21, 2015
    Publication date: August 24, 2017
    Inventors: David PASTRE, Michel CAILLERET, Patrick CURMI, Mirela BOCA